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Making recombinant extracellular matrix proteins
Methods, 2008A variety of approaches to understand extracellular matrix protein structure and function require production of recombinant proteins. Moreover, the expression of heterologous extracellular matrix proteins, in particular collagens, using the recombinant technology is of major interest to the biomedical industry.
Ruggiero, Florence, Koch, M.
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Extracellular Matrix Proteins Involved in Alzheimer's Disease
Chemistry – A European Journal, 2020AbstractAlzheimer's disease (AD) is one of the most common neurodegenerative diseases and characterized by cognitive and memory impairments. Emerging evidence suggests that the extracellular matrix (ECM) in the brain plays an important role in the etiology of AD.
Jun Ma +6 more
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Extracellular matrix proteins of dentine.
Ciba Foundation symposium, 1997Bone and dentine extracellular matrix proteins are similar, consisting primarily of type I collagen, acidic proteins and proteoglycans. Although collagen forms the lattice for deposition of calcium and phosphate for formation of carbonate apatite, the non-collagenous proteins are believed to control initiation and growth of the crystals.
W T, Butler +2 more
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MOLECULAR BIOLOGY OF THE EXTRACELLULAR MATRIX PROTEINS
Biological Reviews, 1988Summary1. Extracellular matrices are organized networks of diverse macromolecules, secreted and deposited in the vicinity of cells. They not only play structural roles but are also involved in dynamic processes such as cell migration and differentiation, embryo development, wound healing and cancerous transformation.
A R, Kornblihtt, A, Gutman
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Binding of extracellular matrix proteins by lactobacilli
Folia Microbiologica, 2001Ten gut and ten vaginal Lactobacillus strains were investigated for their ability to bind type I collagen (Cn-I) and four selected gut lactobacilli were investigated for their binding to other extracellular matrix (ECM) molecules. Immobilized Cn-I (100 mg/L) in wells of microtitre plates was bound by all 10 autoaggregating vaginal strains and by 3 ...
I, Styriak, B, Zatkovic, S, Marsalková
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Extracellular matrix proteins and leukocyte function
Journal of Leukocyte Biology, 1995Abstract Extracellular matrix (ECM) proteins profoundly affect physiological functioning at the cellular level. Cell growth and differentiation, as well as cell shape and migration via the cytoskeleton, are all affected by ECM proteins.
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Interactions of bacteria with extracellular matrix proteins
Cell Differentiation and Development, 1990Cell adhesion is a critical factor in microbial life. For commensal or saprophytic bacteria, attachment is a question of survival, while in pathogenic bacteria adherence to a particular site may initiate an infection. In addition to nonspecific forces, which seem to play some role, adhesion of bacteria is predominantly dependent upon specific ...
Magnus Hook +8 more
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Binding of Extracellular Matrix Proteins by Enterococci
Current Microbiology, 1997Forty-four enterococcal strains isolated from human clinical specimens were investigated for binding of 125I-labeled fibronectin, vitronectin, thrombospondin, lactoferrin, and collagen type I and IV, and for cell surface hydrophobicity. Most strains expressed low binding of iodine-labeled human fibronectin, collagen I and IV, and higher binding of ...
T W, Zareba +3 more
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