Results 111 to 120 of about 344,575 (257)

Correction: Oligomeric states of ASC specks regulate inflammatory responses by inflammasome in the extracellular space. [PDF]

Cell Death Discov, 2023
Yu TG, Cha JS, Kim G, Sohn YK, Yoo Y, Kim U, Song JJ, Cho HS, Kim HS.   +8 more
europepmc   +1 more source

Synergistic Osteogenesis After Co‐Administration of cmRNAs Encoding BMP‐2 and BMP‐7 Utilizing a Transcript‐Activated Matrix

Advanced Functional Materials, EarlyView.
This study demonstrates that the dual delivery of BMP‐2/‐7 coding cmRNAs for bone healing is demonstrated as feasible, safe, and highly osteogenic. Compared to single BMP‐2 or BMP‐7 cmRNAs, the combination enhances the production of both mineral and organic components of the extracellular matrix when delivered using a collagen‐HA scaffold, supporting ...
Claudia Del Toro Runzer, Joanna M. Sadowska, Nadia Roumans, Christian Plank, Christopher H. Evans, Fergal J. O'Brien, Martijn van Griensven, Elizabeth R. Balmayor   +7 more
wiley   +1 more source

Herpes simplex virus type 1 glycoprotein K is not essential for infectious virus production in actively replicating cells but is required for efficient envelopment and translocation of infectious virions from the cytoplasm to the extracellular space [PDF]

, 1997
Jayachandra S. Yaradoddi, Abolghasem Baghian, Konstantin G. Kousoulas   +2 more
openalex   +1 more source

THE INFLUENCE OF INCREASED EXTRACELLULAR SPACE VOLUME ON THE TOXIN EXCRETORY FUNCTION OF THE KIDNEYS IN PATIENTS WITH DOPAMINE-DEPENDENT COMPENSATED SEPSIS-INDUCED HYPOTENSION IN CASE OF PURULENT-SEPTIC COMPLICATIONS

, 2023
А. В. Андрущак, В. M. Коновчук, Sergij Kushrir, Mykola Kokalko   +3 more
openalex   +2 more sources

Patterning the Void: Combining L‐Systems with Archimedean Tessellations as a Perspective for Tissue Engineering Scaffolds

Advanced Functional Materials, EarlyView.
This study introduces a novel multi‐scale scaffold design using L‐fractals arranged in Archimedean tessellations for tissue regeneration. Despite similar porosity, tiles display vastly different tensile responses (1–100 MPa) and deformation modes. In vitro experiments with hMSCs show geometry‐dependent growth and activity. Over 55 000 tile combinations
Maria Kalogeropoulou, Kenny A. van Kampen, Pierpaolo Fucile, Carlos Mota, Lorenzo Moroni   +4 more
wiley   +1 more source

3D Multicellular Scaffold Based Model for Advancing Bone Disorder Research

Advanced Functional Materials, EarlyView.
A scalable 3D multicellular in vitro bone model engineered by integrating osteoblasts, osteoclasts, and endothelial cells on biodegradable scaffolds. The system recapitulates key features of human bone remodeling and disease pathology. As a proof of concept, the model mimics osteogenesis imperfecta, demonstrating its potential as a physiologically ...
Gali Guterman‐Ram, Majd Machour, Janette Zavin, Roy Meretzki, Reut Lev‐Ari, Shulamit Levenberg   +5 more
wiley   +1 more source

Thiol Modifications in the Extracellular Space-Key Proteins in Inflammation and Viral Infection. [PDF]

Front Immunol, 2022
Brücksken KA, Loreto Palacio P, Hanschmann EM.   +2 more
europepmc   +1 more source

Substrate Stress Relaxation Regulates Cell‐Mediated Assembly of Extracellular Matrix

Advanced Functional Materials, EarlyView.
Silicone‐based viscoelastic substrates with tunable stress relaxation reveal how matrix mechanics regulates cellular mechanosensing and cell‐mediated matrix remodelling in the stiff regime. High stress relaxation promotes assembly of fibronectin fibril‐like structures, increased nuclear localization of YAP and formation of β1 integrin‐enriched ...
Jonah L. Voigt, Jens Timmer, Elisabetta Ada Cavalcanti‐Adam   +2 more
wiley   +1 more source

Is There a Role for Immunoregulatory and Antiviral Oligonucleotides Acting in the Extracellular Space? A Review and Hypothesis. [PDF]

Int J Mol Sci, 2022
Dondalska A, Axberg Pålsson S, Spetz AL.   +2 more
europepmc   +1 more source

Author Response: Disulfide bridge-dependent dimerization triggers FGF2 membrane translocation into the extracellular space

, 2023
Fabio Lolicato, JP Steringer, Roberto Saleppico, Dániel Beyer, J Fernandez-Sobaberas, Sonja Unger, Steffen Klein, Petra Riegerová, Sabine Wegehingel, Hans‐Michael Müller, XJ Schmitt, Shreyas Kaptan, Christian Freund, Martin Hof, Radek Šachl, Petr Chlanda, Ilpo Vattulainen, Walter Nickel   +17 more
openalex   +1 more source