Results 121 to 130 of about 5,853,415 (367)
A Multidomain Model for Ionic Electrodiffusion and Osmosis with an Application to Cortical Spreading Depression [PDF]
, 2014 Ionic electrodiffusion and osmotic water flow are central processes in many physiological systems. We formulate a system of partial differential equations that governs ion movement and water flow in biological tissue.
Mori, Yoichiro
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FEBS Open Bio, EarlyView.Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui +3 more
wiley +1 more source
Heuristic Spike Sorting Tuner (HSST), a framework to determine optimal parameter selection for a generic spike sorting algorithm [PDF]
, 2020 Extracellular microelectrodes frequently record neural activity from more than one neuron in the vicinity of the electrode. The process of labeling each recorded spike waveform with the identity of its source neuron is called spike sorting and is often ...
Bjånes, David A. +3 more
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FEBS Open Bio, EarlyView.Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp +13 more
wiley +1 more source
, 2012 The simulation data presented here, and the conceptual framework developed for their interpretation are, both, in need of substantial refinement and extension.
Werner, prof. Gerhard
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FEBS Open Bio, EarlyView.Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley +1 more source
Extracellular α-synuclein levels are regulated by neuronal activity
Molecular Neurodegeneration, 2018 Background α-Synuclein is a presynaptic protein abundant in the cytoplasmic compartment of neurons, whereas its presence in the extracellular space has also been observed under physiological conditions.
Kaoru Yamada, Takeshi Iwatsubo
doaj +1 more source
A mathematical model for calculating the effect of toroidal geometry on the measured magnetic field [PDF]
, 2009 A mathematical model to calculate the measured magnetic field from a stimulated nerve has been presented in the past. Traditionally, electrodes have been used to measure these propagating action signals in nerves, but a less invasive technique is to use ...
Skoczelas, Brenda M.
core +1 more source