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3D‐Printed Corneal Substitutes: Materials, Fabrication, and Preclinical Progress
Successful clinical translation of 3D‐printed corneal substitutes relies on the interplay between the bioink properties, cellular component, and the fabrication process. These factors influence the critical properties of the construct, including optical transparency, mechanical stability, suture retention, that ultimately govern long‐term stromal ...
Shadi Moshayedi +4 more
wiley +1 more source
A collagen‐based gut‐on‐chip model replicates the intestinal extracellular matrix, supporting villi‐like structures, tight junctions, and mucin production. This biomimetic platform enables rapid epithelial differentiation and functional barrier formation.
Fernanda López García +4 more
wiley +1 more source
A Cryopreservation‐Based Supply Chain Strategy for Extrusion Bioprinting in Space
Extrusion bioprinting on crewed space platforms requires a bioink that stays functional along the logistic chain. Here, cells and biomaterial ink travel separately, the cells cryopreserved and the ink cold stored, and are combined only minutes before printing.
Johannes Windisch +7 more
wiley +1 more source
Editorial: Brain Extracellular Space: Geometry, Matrix and Physiological Importance
Padideh Kamali-Zare, Charles Nicholson
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Alarmins of the extracellular space
Seminars in Immunology, 2018The ability of the immune system to discriminate between healthy-self, abnormal-self, and non-self has been attributed mainly to alarmins signaling as "danger signals". It is now evident, however, that alarmins are much more complex and can perform specialized functions that can regulate a wide spectrum of processes ranging from propagation of disease ...
Jenna L, Dziki +2 more
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The extracellular space of the lens
Experimental Eye Research, 1965The extracellular space of rat, rabbit and calf lenses has been estimated in vitro using radioactive non-metabolized carbohydrates and 24Na as test substances. The size of the extracellular space ranges from 4 to 13% of the lens water, depending on the test substance used.
R A, Thoft, J H, Kinoshita
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Selective Radioprotection in Extracellular Space
Radiology, 1974Most radioprotective agents are not discriminatory as they can protect both tumor and healthy tissue. The effects of radioprotective agents on radiation-induced free radicals in the extracellular ground substance were investigated by ESR spectroscopy.
R A, Peckauskas, M, Rotman, I, Pullman
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Glucose Concentration in Subcutaneous Extracellular Space
Diabetes Care, 1993OBJECTIVE To compare the subcutaneous glucose sensor measurements with two reference methods. Previous studies provide conflicting findings about the real glucose concentrations in subcutaneous tissue. Some suggest substantially lower concentration, whereas others measure proportionally higher glucose concentrations
SCHMIDT, FJ, SLUITER, WJ, SCHOONEN, AJM
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The extracellular space and matrix of gliomas
Acta Neuropathologica, 2005Changes in the properties of extracellular space (ECS)--its volume, shape, and composition--play an important role in influencing the biological behavior of brain tumors. Experimental methods allowing assessment of the volume and geometry of ECS by means of analyzing the diffusion of molecules within ECS have revealed a dramatic increase in the ECS ...
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Tracking extracellular space in the brain
Science, 2016Neuroscience Extracellular space takes up a large percentage of the brain. Its size changes with the sleep-wake cycle but also during brain development and normal aging, as well as under pathological conditions such as neurodegeneration. Godin et al. injected near-infrared luminescent carbon nanotubes into rat brains and tracked their diffusion in the ...
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