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Advanced Healthcare Materials, EarlyView.ABSTRACT Magnetogenetic deep brain stimulation (MG‐DBS) represents a wireless neuromodulation that has demonstrated long‐lasting behavioral benefits in Parkinson's disease models. However, the circuit‐level mechanisms underlying these therapeutic effects have remained uncharacterized due to limitations of conventional neural interfaces.
Jakyoung Lee +10 more
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Editorial: Brain Extracellular Space: Geometry, Matrix and Physiological Importance
Basic and Clinical Neuroscience, 2013 Padideh Kamali-Zare, Charles Nicholson
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Alarmins of the extracellular space
Seminars in Immunology, 2018The ability of the immune system to discriminate between healthy-self, abnormal-self, and non-self has been attributed mainly to alarmins signaling as "danger signals". It is now evident, however, that alarmins are much more complex and can perform specialized functions that can regulate a wide spectrum of processes ranging from propagation of disease ...
Jenna L, Dziki +2 more
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The extracellular space of the lens
Experimental Eye Research, 1965The extracellular space of rat, rabbit and calf lenses has been estimated in vitro using radioactive non-metabolized carbohydrates and 24Na as test substances. The size of the extracellular space ranges from 4 to 13% of the lens water, depending on the test substance used.
R A, Thoft, J H, Kinoshita
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Selective Radioprotection in Extracellular Space
Radiology, 1974Most radioprotective agents are not discriminatory as they can protect both tumor and healthy tissue. The effects of radioprotective agents on radiation-induced free radicals in the extracellular ground substance were investigated by ESR spectroscopy.
R A, Peckauskas, M, Rotman, I, Pullman
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Glucose Concentration in Subcutaneous Extracellular Space
Diabetes Care, 1993OBJECTIVE To compare the subcutaneous glucose sensor measurements with two reference methods. Previous studies provide conflicting findings about the real glucose concentrations in subcutaneous tissue. Some suggest substantially lower concentration, whereas others measure proportionally higher glucose concentrations
SCHMIDT, FJ, SLUITER, WJ, SCHOONEN, AJM
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The Extracellular Space of Voluntary Muscle Tissues [PDF]
Journal of General Physiology, 1967 The volume occupied by the extracellular space has been investigated in six types of voluntary muscles: sartorius (frog), semitendinosus (frog), tibialis anticus longus (frog), iliofibularis (frog), rectus abdominis (frog), and diaphragm (rat). With the aid of four types of probe material, three of which are conventionally employed (inulin, sorbitol ...
G N, Ling, M H, Kromash
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The extracellular space and matrix of gliomas
Acta Neuropathologica, 2005Changes in the properties of extracellular space (ECS)--its volume, shape, and composition--play an important role in influencing the biological behavior of brain tumors. Experimental methods allowing assessment of the volume and geometry of ECS by means of analyzing the diffusion of molecules within ECS have revealed a dramatic increase in the ECS ...
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Tracking extracellular space in the brain
Science, 2016Neuroscience Extracellular space takes up a large percentage of the brain. Its size changes with the sleep-wake cycle but also during brain development and normal aging, as well as under pathological conditions such as neurodegeneration. Godin et al. injected near-infrared luminescent carbon nanotubes into rat brains and tracked their diffusion in the ...
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Extracellular superoxide dismutase (SOD3): An antioxidant or prooxidant in the extracellular space?
2020Superoxide dismutase 3 (SOD3 or EC-SOD) is the only scavenger of superoxide in the extracellular space allowing for the catalyzed dismutation of the superoxide radical into hydrogen peroxide. The activity and distribution of the enzyme are regulated at several levels, suggesting the need for balanced activity in the extracellular space.
Zachariae, Elias Didrik Francis M +2 more
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