Results 11 to 20 of about 13,987 (204)

Molecular mechanisms of extrachromosomal circular DNA formation. [PDF]

Nucleic Acids Res
Abstract Recent research reveals that eukaryotic genomes form circular DNA from all parts of their genome, some large enough to carry whole genes. In organisms like yeast and in human cancers, it is often observed that extrachromosomal circular DNA (eccDNA) benefits the individual cell by providing resources for rapid cellular growth ...
Eugen-Olsen RAB, Hariprakash JM, Oestergaard VH, Regenberg B.   +3 more
europepmc   +6 more sources

Extrachromosomal circular DNA and their roles in cancer progression [PDF]

Genes and Diseases
Extrachromosomal circular DNA (eccDNA), a chromosome-independent circular DNA, has garnered significant attention due to its widespread distribution and intricate biogenesis in carcinoma.
Siqi Zheng, Yunong Li, Lin Wang, Qian Wei, Minjie Wei, Tao Yu, Lin Zhao   +6 more
doaj   +4 more sources

Extrachromosomal circular DNA: enlightenment to widespread clinical application [PDF]

Holistic Integrative Oncology
Shun Wang, Hongrui Li, Yi Zhang, Jian Yan, Wenbin Li   +4 more
doaj   +3 more sources

Categorizing Extrachromosomal Circular DNA as Biomarkers in Serum of Cancer [PDF]

Biomolecules
Extrachromosomal circular DNA (eccDNA), a double-stranded circular DNA molecule found in multiple organisms, has garnered an increasing amount of attention in recent years due to its close association with the initiation, malignant progression, and ...
Enze Deng, Xiaoying Fan
doaj   +4 more sources

Extrachromosomal circular DNA of multiple myeloma. [PDF]

J Cancer
Li F, Long X, Tang S, Liu J, Fu Y.
europepmc   +4 more sources

Deciphering extrachromosomal circular DNA in Arabidopsis

Computational and Structural Biotechnology Journal, 2021
Extrachromosomal circular DNA (eccDNA) is independent of the chromosome and exists in many eukaryotes. However, the nature and origin of eccDNA in plants remains unclear.
Keyi Wang, Hui Tian, Lequn Wang, Lin Wang, Yacong Tan, Ziting Zhang, Kai Sun, Meng Yin, Qinggong Wei, Baohua Guo, Jinyu Han, Peiru Zhang, Han Li, Yulong Liu, Hongwei Zhao, Xiaoyong Sun   +15 more
doaj   +3 more sources

Extrachromosomal circular DNA: Current status and future prospects

eLife, 2022
Extrachromosomal circular DNA (eccDNA) is a double-stranded DNA molecule found in various organisms, including humans. In the past few decades, the research on eccDNA has mainly focused on cancers and their associated diseases.
Yiheng Zhao, Linchan Yu, Shuchen Zhang, Xiangyu Su, Xiang Zhou   +4 more
doaj   +3 more sources

TeCD: The eccDNA Collection Database for extrachromosomal circular DNA

BMC Genomics, 2023
Background Extrachromosomal circular DNA (eccDNA) is a kind of DNA that widely exists in eukaryotic cells. Studies in recent years have shown that eccDNA is often enriched during tumors and aging, and participates in the development of cell physiological
Jing Guo, Ze Zhang, Qingcui Li, Xiao Chang, Xiaoping Liu   +4 more
doaj   +3 more sources

Extrachromosomal Circular DNA (eccDNA): From Chaos to Function [PDF]

Frontiers in Cell and Developmental Biology, 2022
Extrachromosomal circular DNA (eccDNA) is a type of double-stranded circular DNA that is derived and free from chromosomes. It has a strong heterogeneity in sequence, length, and origin and has been identified in both normal and cancer cells.
Shanru Zuo, Shanru Zuo, Yihu Yi, Chen Wang, Xueguang Li, Mingqing Zhou, Qiyao Peng, Qiyao Peng, Junhua Zhou, Yide Yang, Quanyuan He   +10 more
doaj   +3 more sources

Extrachromosomal Circular DNA: A New Target in Cancer

Frontiers in Oncology, 2022
Genomic instability and amplification are intrinsically important traits determining the development and heterogeneity of tumors. The role of extrachromosomal circular DNA (eccDNA) in tumors has recently been highlighted.
Pan Wu, Pan Wu, Pan Wu, Yuhang Liu, Yuhang Liu, Yuhang Liu, Ruijia Zhou, Ruijia Zhou, Ruijia Zhou, Lingyun Liu, Hongli Zeng, Fang Xiong, Shanshan Zhang, Zhaojian Gong, Wenling Zhang, Wenling Zhang, Can Guo, Fuyan Wang, Ming Zhou, Xuyu Zu, Zhaoyang Zeng, Yong Li, Guiyuan Li, He Huang, He Huang, He Huang, Wei Xiong, Wei Xiong, Wei Xiong   +28 more
doaj   +3 more sources