Results 111 to 120 of about 2,028,297 (227)
Advanced Science, Volume 12, Issue 25, July 3, 2025.Extrachromosomal Circular DNA In article number 2501934, Bin Shi, Shuyu Zhang, and co‐workers present the increased existence of eccDNA induced by ionizing radiation. VPS41 gene in the eccDNA confers protection against genotoxic stress. This study highlights the role of eccDNA in cellular defense, providing strategies to enhance tissue resilience to ...
Bin Shi +12 more
wiley +1 more source
The extrachromosomal circular DNA atlas of aged and young mouse brains
Scientific DataExtrachromosomal circular DNA (eccDNA) refers to a distinct class of circular DNA molecules that exist independently from linear chromosomal DNA. Extensive evidence has firmly established the significant involvement of eccDNA in cancer initiation ...
Xiaoning Hong +8 more
doaj +1 more source
Therapies for Mitochondrial Disease: Past, Present, and Future
Journal of Inherited Metabolic Disease, Volume 48, Issue 4, July 2025.ABSTRACT Mitochondrial disease is a diverse group of clinically and genetically complex disorders caused by pathogenic variants in nuclear or mitochondrial DNA‐encoded genes that disrupt mitochondrial energy production or other important mitochondrial pathways. Mitochondrial disease can present with a wide spectrum of clinical features and can often be
Megan Ball +5 more
wiley +1 more source
Genomic function during the lampbrush chromosome stage of amphibian oogenesis [PDF]
, 1966 Throughout its lengthy developmental history the disposition of the genetic material in the amphibian oocyte nucleus differs from that in other cell types.
Crippa, Marco +3 more
core +1 more source
Agricultural biotechnology: Potential, challenges, and debate
PLANTS, PEOPLE, PLANET, EarlyView.
Marjorie R. Lundgren +2 more
wiley +1 more source
Environmental Microbiology, Volume 27, Issue 7, July 2025.In anoxic sediments of the meromictic freshwater Lake Cadagno ‘Ca. Methanoperedens’ and sulphate‐reducing Desulfobacterota QYQD01 co‐occur. Metagenomics revealed that ‘Ca. Methanoperedens’ genomes harbour different extracellular electron transfer pathways.
Maider J. Echeveste Medrano +7 more
wiley +1 more source
FEBS Open Bio, Volume 15, Issue 6, Page 906-913, June 2025.Heterologous expression of membrane transporters in cultured cells is essential for functional characterization, but is sometimes limited by low activity. Our study compares the HDAC inhibitors butyrate, VPA and SAHA to enhance transport activity. We propose to replace butyrate by SAHA: it is equally effective, devoid of repulsive odor, costs less, and
Svenja Flögel +4 more
wiley +1 more source
The role of the N-acetylglucosamine phosphoenolpyruvate phosphotransferase system from Lactobacillus plantarum 8014 in the mechanism of action of glycocin F : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University, Manawatū, New Zealand [PDF]
, 2017 The rise in antibiotic-resistant bacteria is becoming a severe public health problem because of the shortage of new antibiotics to combat existing resistant bacterial pathogens.
Bailie, Marc Alex
core
Overlooked: Extrachromosomal DNA and Their Possible Impact on Whole Genome Sequencing
Malaysian Journal of Medical Sciences, 2018 Extrachromosomal (ec) DNA in eukaryotic cells has been known for decades. The structures described range from linear double stranded (ds) DNA to circular dsDNA, distinct from mitochondrial (mt) DNA.
R. Dennin
semanticscholar +1 more source
Extrachromosomal nucleic acids in bovine babesia
Memorias do Instituto Oswaldo Cruz, 1992 Two kinds of small extrachromosomal nucleic acid elements were found in the bovine babesias, Babesia bovis and B. bigemina. One element with an apparent size of 5.5 kilobase pairs (kbp) is a double stranded RNA related to virus like particles.
Isidro Hotzel +5 more
doaj +1 more source