Results 61 to 70 of about 32,224 (195)

Paediatric Index of Mortality 3 in Sweden: Validation and Recalibration to Improve Mortality Prediction in Paediatric Intensive Care

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim In Sweden, critically ill children are admitted to one of four dedicated paediatric intensive care units (PICUs) or general intensive care units (ICUs), reflecting a partly centralised system. The Paediatric Index of Mortality 3 (PIM3) is a widely used risk stratification tool for predicting mortality in critically ill children. This study
Lars Engerström   +4 more
wiley   +1 more source

The platelets in extracorporeal circulation [PDF]

open access: yes, 1997
Over the last decade extracorporeal life support (ECLS) has been increasingly used in the management of life-threatening respiratory failure in children and in adults.
Mellgren, Karin 1962-
core  

Heparin-coated extracorporeal circulation systems in heart surgery [PDF]

open access: yes, 2009
Despite the progress accomplished in the field of off-pump heart surgery, the vast majority of cardiac operations are still performed with the use of extracorporeal circulation, otherwise known as "heart-lung machine." This valuable tool, however, is ...
Tagarakis, G. I., Tsilimingas, N. B.
core   +1 more source

Refining the treatment of immune checkpoint inhibitor–associated myocarditis: Challenges, innovations and rechallenge considerations

open access: yesBritish Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitor (ICI)‐associated myocarditis has emerged as a severe and clinically complex immune‐related toxicity that poses significant challenges for therapeutic decision‐making in routine cardio‐oncological care. High‐dose corticosteroids remain the first‐line therapy, yet their timing, dosage and tapering require careful clinical ...
Raluca I. Mincu   +10 more
wiley   +1 more source

Phase IIB, Randomized, Double‐Blind, Placebo‐Controlled Clinical Trial of Intravenous Defibrotide for the Prevention and Treatment of Respiratory Distress and Cytokine Release Syndrome in COVID‐19

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Introduction Endothelial dysfunction is key in COVID‐19 pathogenesis. This randomized, double‐blind phase IIb trial investigated continuous intravenous infusion of defibrotide in patients hospitalized with SARS‐CoV‐2 infection and respiratory failure.
Ruben Jara Rubio   +38 more
wiley   +1 more source

The Top Five Advances in Solid Organ Transplantation in the Past Fifty Years

open access: yes
World Journal of Surgery, EarlyView.
Stephen J. Wigmore, Diana A. Wu
wiley   +1 more source

Extended Double Plasma Molecular Adsorption Sessions and Bilirubin Clearance: A Case Report

open access: yesHemodialysis International, EarlyView.
ABSTRACT Background The double plasma molecular adsorption system is an artificial‐liver treatment model combining the use of ion exchange resins and neutral microporous resins to remove toxins such as inflammatory cytokines without consuming large amounts of plasma and albumin. Given the relatively expensive consumables needed for Bilirubin adsorption,
Hui Ye   +7 more
wiley   +1 more source

Mapping malignant T‐cell states and immune circuits in Sézary syndrome by single‐cell analysis

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
Peripheral blood single‐cell RNA‐seq from leukaemic CTCL defined three malignant T‐cell programmes: MTC CM, MTC Reg and MTC E/EM, each with distinct features and candidate vulnerabilities. For example, inferred immune circuits highlighted actionable IL‐10/JAK–TYK2–STAT3 signalling, KIR–MHC I inhibitory interactions and myeloid/B‐cell inflammatory and ...
Beth A. Childs   +6 more
wiley   +1 more source

Model of extracorporeal circulation [PDF]

open access: yes, 2018
Model mimotělního oběhu Mimotělní oběh je komplexní forma podpory životních funkcí pacienta během náročných kardiochirurgických operací, která nahrazuje funkci srdce a plic.
Ličková Vanda
core  

Comparison of noradrenalin medication during cardio surgeries using extracorporeal circulation [PDF]

open access: yes, 2008
The theme of this thesis is a comparison of two methods of medication a noradrenalin hormone during surgeries using extracorporeal circulation. Both of these methods - continuous and bolus medication are common used in praxis to regulate blood pressure ...
Samková, Markéta
core   +2 more sources

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