Results 81 to 90 of about 655,486 (246)

Reverse‐Engineered Lipid Nanoparticles Harness Protein Corona Formation for Cytokine Sequestration and Combination Immunomodulatory Therapy

open access: yesSmall, EarlyView.
Bioinspired triglyceride‐ceramide lipid nanoparticles were reverse‐engineered from cytokine‐sequestering plant‐derived nanoparticles to capture pathological inflammatory mediators through protein corona formation. Dexamethasone‐loaded TCNPs combine extracellular cytokine sequestration with intracellular immunomodulation, reducing IL‐6, TNF‐α, and NF‐κΒ
Junsik J. Sung   +2 more
wiley   +1 more source

Extracorporeal Circulation as a New Experimental Pathway for Myoblast Implantation in mdx Mice

open access: yesCell Transplantation, 1999
The deficiency of dystrophin, a sarcolemmal associated protein, is responsible for Duchenne muscular dystrophy (DMD). Gene replacement is attractive as a potential therapy.
Y. Torrente   +11 more
doaj   +1 more source

Minimized Extracorporeal Circulation does not impair cognitive brain function after coronary artery bypass grafting

open access: yes, 2015
Gebiet: Chirurgie Abstract: Minimized Extracorporeal Circulation does not impair cognitive brain function after coronary artery bypass grafting – – Objectives – Objective evaluation of the impact of minimized extracorporeal circulation (MECC) on ...
Winkler, Bernhard
core  

Efficiency comparison between new single‐needle dialysis and conventional double‐needle dialysis and exploration of the optimal prescription parameters for single‐needle hemodialysis

open access: yesTherapeutic Apheresis and Dialysis, Volume 29, Issue 3, Page 419-427, June 2025.
Abstract Objective To compare the dialysis efficiency parameters between new single‐needle dialysis and conventional double‐needle dialysis and to explore the optimal prescription parameters for single‐needle hemodialysis. Methods This study involved a prospective, cross‐over design. Eight patients were randomly divided into two cohorts, which received
Bin Zhao   +8 more
wiley   +1 more source

Troubleshooting in extracorporeal life support

open access: yesSwiss Medical Weekly, 2015
Since the first clinical use of extracorporeal circulation in the last century by John Gibbon and the first successful mechanical support of the left ventricular function by Forest Dodrill, the progress of techniques and technologies has helped to ...
Denis Berdajs
doaj   +1 more source

Evaluation of Hemodynamic and Regional Tissue Perfusion Effects of Minimized Extracorporeal Circulation (MECC®)

open access: yes, 2010
Minimized extracorporeal circulation (MECC®, Maquet, Cardiopulmonary AG, Hirrlingen, Germany) is an established procedure to perform coronary revascularization. Studies showed positive effects of MECC compared to conventional cardiopulmonary bypass (CCPB)
Nagi El-Shouki   +6 more
core   +1 more source

Post‐Market Analysis of the Xenios Console With the Xlung Tubing Kit 230 for Extracorporeal Membrane Oxygenation After Cardiac Surgery

open access: yesArtificial Organs, EarlyView.
This study is a comprehensive post‐market analysis of the Xenios console and XLung kit 230 preconfigured ECMO tubing set in post‐cardiotomy applications. The performance of this device was evaluated and demonstrated in all key clinical areas, with an adequate safety profile.
Luca Conci   +9 more
wiley   +1 more source

Progress and clinical applications of minimally invasive extracorporeal circulation technology

open access: yesZhongguo Linchuang Yixue
Extracorporeal circulation serves as a vital auxiliary approach in cardiac surgery, and its introduction and application have directly driven a clinical revolution in cardiac surgical procedures.
Jiaxing Wang, Xiaowei Shen, Yun Zhao
doaj   +1 more source

Fulminant myocarditis managed with pulsatile extracorporeal life support; use of Twin Pulse Life support (T-PLS®)

open access: yesJournal of Cardiothoracic Surgery, 2011
Fulminant myocarditis frequently results in severe hemodynamic deterioration. High-dose vasopressors or sometimes mechanical circulatory support are required.
Cho Eun   +4 more
doaj   +1 more source

An Optimized Multi‐Stage Drainage Cannula Design for Venoarterial Extracorporeal Membrane Oxygenation

open access: yesArtificial Organs, EarlyView.
This study utilized an extensive optimization involving n = 540 design of experiments to produce a superior drainage cannula design. Compared to the clinically used Maquet model, our optimized design demonstrated reduced blood stagnation volumes, increased cannula tip velocities, and higher upper body drainage, potentially minimizing risk of thrombosis
Avishka Wickramarachchi   +3 more
wiley   +1 more source

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