Results 91 to 100 of about 33,391 (242)

Zebrafish as a practical and convenient model for the study of photodynamic and photothermal therapy of solid tumors: A scoping review

Photochemistry and Photobiology, EarlyView.
Zebrafish provide a high‐throughput, optically transparent platform for cancer and drug screening. Their ~80% genetic homology, xenograft compatibility, and transgenic strains enable targeted photosensitizer screening, real‐time ROS and tumor imaging, and mechanistic assays, while fish embryo acute toxicity (FET) and in vitro tests streamline toxicity ...
Ethan Wilson, Alexander Fiorentino, Brian W. Booth, Valery Bliznyuk, Diana Ivankovic, Luigi Boccuto   +5 more
wiley   +1 more source

How necessary are randomized controlled trials? [PDF]

, 1992
Randomized controlled trials (RCTs) are often deemed the gold standard for testing new treatments. This belief in turn justifies recruiting patients into such trials even when it is suspected that a new treatment is superior – although patients in the ...
Northcott, Robert
core  

Lessons learned from ECMO support in pediatric patients with D-transposition of the great arteries: preoperative, intraoperative and postoperative

World Journal of Pediatric Surgery, 2021
Qiang Shu, Jiangen Yu, Jianhua Li, Lijun Yang, Ru Lin, Lifen Ye, Zewei Zhang   +6 more
doaj   +1 more source

Pericardiectomy with routine cardiopulmonary bypass: a multicenter, randomized controlled trial

Trials
Constrictive pericarditis is a result of chronic inflammation characterized by thickening and calcification of pericardial fibers, impaired diastolic filling, reduced cardiac output, and ultimately heart failure.
Jing-bin Huang, Chang-chao Lu, Zhao-ke Wen   +2 more
doaj   +1 more source

Intra‐apheresis CD34+ cell count: A dynamic approach to predicting peripheral blood stem cell collection yield

Transfusion, EarlyView.
Abstract Background Accurate prediction of peripheral blood stem cell (PBSC) yield is essential for optimizing hematopoietic stem cell collections. Traditional CD34+ prediction formulas often overlook the ongoing recruitment of CD34+ cells during the collection procedure.
Abdullah Alswied, Linda Song, Mame Thioye‐Sall, Leonard N. Chen, Kamille West‐Mitchell, Nan Zhang, Ping Jin, David Stroncek, Anh Dinh   +8 more
wiley   +1 more source

Research Progress on Influence of Centrifugal Blood Pump on Blood Injury

Zhongguo yiliao qixie zazhi
Centrifugal blood pumps drive blood flow by regulating blood flow rate, and have been widely used in clinical applications, including extracorporeal membrane oxygenation (ECMO), cardiopulmonary bypass (CPB), and extracorporeal circulation carbon dioxide ...
Chenghong YE, Yanguo ZOU, Jie LI, Yuxi YANG, Yongqing WANG   +4 more
doaj   +1 more source

Advances in cardiac devices and bioelectronics augmented with artificial intelligence

The Journal of Physiology, EarlyView.
Abstract figure legend Interfaces between the human heart, diagnostic bioelectronics, artificial intelligence, and clinical care. From left to right: Human heart and biosensor interface; representative waveforms of common diagnostic bioelectronic sensing modalities.
Charles Stark, Eric Rytkin, Andrei Alexandru Mircea, Igor R. Efimov   +3 more
wiley   +1 more source

Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

, 2006
Background— Stem and progenitor cell therapy is a novel approach to improve neovascularization and function of ischemic tissue. Enhanced tissue expression of chemoattractant factors such as stromal cell–derived factor 1 and vascular endothelial growth ...
Dimmeler, S, Aicher, A, Heeschen, C, Sasaki, K, Urbich, C, Zeiher, AM   +5 more
core  

Extracorporeal Circulation During Treatment of Aneurysms of the Ascending Aorta

, 2023
Extracorporeal circulation in the treatment of aneurysms of the ascending aorta and transverse arch present both the surgeon and perfusionist with a formidable challenge.
Russell R. Butler, Alfred H. Stammers, Marvin M. Kirsh   +2 more
core   +1 more source

Deciphering pro‐arrhythmogenic mechanisms of EPAC in human atrial cardiomyocytes

The Journal of Physiology, EarlyView.
Abstract figure legend This study aimed to investigate the effect of exchange proteins directly activated by cAMP (EPAC) on the regulation of human atrial cardiomyocyte electrophysiology and their potential involvement in the onset of atrial fibrillation (AF).
Arthur Boileve, Margaux Aize, Maximin Détrait, Laura Brard, Adrien Leboyer, Pierre‐Antoine Dupont, Alexandre Lebrun, Vladimir Saplacan, Christophe Simard, Fabien Brette, Frank Lezoualc'h, Laurent Sallé   +11 more
wiley   +1 more source