Results 101 to 110 of about 725,174 (193)
ABSTRACT Background Transvenous lead extraction (TLE) for cardiac implantable electronic device infection has high procedural success, but with a 1‐year mortality approaching 25%. Potential mechanisms include septic embolization and persistent infected lead casts or “ghosts.” Percutaneous mechanical aspiration of lead‐related vegetations during TLE is ...
Haran Yogasundaram +12 more
wiley +1 more source
The Goldilocks Principle in Neonatal Fluids: Finding the Just‐Right Balance
ABSTRACT The impact of disrupted fluid balance on outcomes in critically unwell children and adults is well described. Recent literature in neonates has demonstrated that both fluid overload and excessive postnatal fluid losses are associated with increased morbidity and mortality.
Jane B. McMahon +7 more
wiley +1 more source
Abstract Background Citrate‐related reactions remain the most common adverse events during peripheral blood stem cell (PBSC) collection despite routine prophylactic intravenous calcium administration. We evaluated whether prophylactic oral calcium–vitamin D3–magnesium supplementation reduces citrate‐related reactions in healthy PBSC donors.
Keiko Fujii +8 more
wiley +1 more source
Surgical myocardial revascularization without extracorporeal circulation
OBJECTIVE: To assess the immediate postoperative period of patients undergoing myocardial revascularization without extracorporeal circulation with different types of grafts.
Vieira, Reinaldo W. +7 more
core
Deciphering pro‐arrhythmogenic mechanisms of EPAC in human atrial cardiomyocytes
Abstract figure legend This study aimed to investigate the effect of exchange proteins directly activated by cAMP (EPAC) on the regulation of human atrial cardiomyocyte electrophysiology and their potential involvement in the onset of atrial fibrillation (AF).
Arthur Boileve +11 more
wiley +1 more source
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
ABSTRACT Immune checkpoint inhibitors (ICIs) have revolutionized the management of patients with cancer. However, they can induce breakdowns in immunologic tolerance, leading to autoimmune diseases, or immune related adverse events (irAEs). These irAEs can sometimes be life threatening, requiring aggressive management, such as immunosuppressant (IS) or
C. Vuillet +36 more
wiley +1 more source
Endotoxins and Biological Implications—Review
Graphical overview of endotoxin sources, exposure routes, biological effects, detection methods, and routes of elimination. ABSTRACT Endotoxins, also known as lipopolysaccharides (LPSs), are structural components of the outer membrane of Gram‐negative bacteria and some cyanobacteria.
Uzair Ishtiaq +5 more
wiley +1 more source
Assessment of suitability of minimal extracorporeal circulation during cardiac surgery [PDF]
Nikitinský, David - Assessment of suitability of minimal extracorporeal circulation during cardiac surgery First Faculty of Medicine Charles University in Prague Thesis supervisor: doc. MUDr. Vilém Rohn, CSc.
Nikitinský, David
core +1 more source
ABSTRACT Introduction Bivalirudin is an alternative anticoagulant to heparin and is widely used in pediatric extracorporeal life support (ECLS). Its activity is monitored using activated partial thromboplastin time (aPTT) and/or more specific tests such as plasma‐diluted thrombin time (dTT).
Vadim Kostousov +3 more
wiley +1 more source

