Results 101 to 110 of about 655,486 (246)

Refining the treatment of immune checkpoint inhibitor–associated myocarditis: Challenges, innovations and rechallenge considerations

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitor (ICI)‐associated myocarditis has emerged as a severe and clinically complex immune‐related toxicity that poses significant challenges for therapeutic decision‐making in routine cardio‐oncological care. High‐dose corticosteroids remain the first‐line therapy, yet their timing, dosage and tapering require careful clinical ...
Raluca I. Mincu, Lisa Zimmer, Dimitra Vlachopoulou, Elias Haj‐Yehia, Julia Hoffmann, Lars Michel, Elisabeth Livingstone, Dirk Schadendorf, Alpaslan Tasdogan, Matthias Totzeck, Tienush Rassaf   +10 more
wiley   +1 more source

Pericardiectomy with routine cardiopulmonary bypass: a multicenter, randomized controlled trial

Trials
Constrictive pericarditis is a result of chronic inflammation characterized by thickening and calcification of pericardial fibers, impaired diastolic filling, reduced cardiac output, and ultimately heart failure.
Jing-bin Huang, Chang-chao Lu, Zhao-ke Wen   +2 more
doaj   +1 more source

Liver Organoids: From Disease Modelling to Regenerative Medicine

Cell Proliferation, EarlyView.
Liver organoids provide a versatile platform for disease modelling and drug discovery, leveraging stem cells and engineering techniques. They bridge research and clinical applications, offering significant potential for advancing precision medicine and regenerative therapies for liver diseases.
Tiepeng Wang, Xiaotian Qu, Jinhong Si, Junkang Meng, Ting Zhang, Shuliang Niu   +5 more
wiley   +1 more source

Research Progress on Influence of Centrifugal Blood Pump on Blood Injury

Zhongguo yiliao qixie zazhi
Centrifugal blood pumps drive blood flow by regulating blood flow rate, and have been widely used in clinical applications, including extracorporeal membrane oxygenation (ECMO), cardiopulmonary bypass (CPB), and extracorporeal circulation carbon dioxide ...
Chenghong YE, Yanguo ZOU, Jie LI, Yuxi YANG, Yongqing WANG   +4 more
doaj   +1 more source

Surgical myocardial revascularization without extracorporeal circulation

, 2017
OBJECTIVE: To assess the immediate postoperative period of patients undergoing myocardial revascularization without extracorporeal circulation with different types of grafts.
Vieira, Reinaldo W., Iasbech, Jose Alberto, Ordinola Rojas, Salomon Soriano, Veiga, Viviane C., Berlinck, Marcos S., Souza, Januario M., Magna, Luiz Alberto, Oliveira, Sergio A.   +7 more
core  

Extended Double Plasma Molecular Adsorption Sessions and Bilirubin Clearance: A Case Report

Hemodialysis International, EarlyView.
ABSTRACT Background The double plasma molecular adsorption system is an artificial‐liver treatment model combining the use of ion exchange resins and neutral microporous resins to remove toxins such as inflammatory cytokines without consuming large amounts of plasma and albumin. Given the relatively expensive consumables needed for Bilirubin adsorption,
Hui Ye, Yi Long Hao, Hai Nan Yang, Wei Fang Yuan, Kai Liang Xu, Xiao Xiao Li, Ming Lei, Yu Xia Sun   +7 more
wiley   +1 more source

Assessment of Thrombin Generation in Pediatric Patients on Extracorporeal Life Support: Impact of Bivalirudin and Other Anticoagulants

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Bivalirudin is an alternative anticoagulant to heparin and is widely used in pediatric extracorporeal life support (ECLS). Its activity is monitored using activated partial thromboplastin time (aPTT) and/or more specific tests such as plasma‐diluted thrombin time (dTT).
Vadim Kostousov, Karen Bruzdoski, Amir Navaei, Jun Teruya   +3 more
wiley   +1 more source

The Sound Environment in the PICU: A Scoping Review Describing Sound Levels, Interventions and Patient Impacts

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Elevated sound levels are associated with increased morbidity in adult and neonatal intensive care; however, their impact in the paediatric intensive care unit (PICU) remains poorly characterised. The aim of this scoping review was to characterise sound exposure in the PICU, including its measurement, sources, and associations with patient ...
Janeen Bower, Hazel Low, Naomi Khan, Sebastian J. Corlette, Emma Macdonald‐Laurs, Andrea Veysey, Ben Gelbart, Kate Masterson   +7 more
wiley   +1 more source

Use of Intralipid Therapy and Therapeutic Plasma Exchange in the Management of Cholecalciferol Rodenticide Exposure in a Dog: A Case Report

Journal of Veterinary Emergency and Critical Care, EarlyView.
ABSTRACT Objective To describe the presentation and outcome of a case of suspected cholecalciferol rodenticide intoxication managed with both intralipid emulsion (ILE) and therapeutic plasma exchange (TPE). Case Summary A 3‐year‐old, neutered female, crossbreed dog presented for acute‐onset vomiting and lethargy after suspected exposure to ...
Tanvi A. Kamat, Kara D. Altman, Emma Donnelly, Neus Elias Santo‐Domingo   +3 more
wiley   +1 more source

Deciphering pro‐arrhythmogenic mechanisms of EPAC in human atrial cardiomyocytes

The Journal of Physiology, EarlyView.
Abstract figure legend This study aimed to investigate the effect of exchange proteins directly activated by cAMP (EPAC) on the regulation of human atrial cardiomyocyte electrophysiology and their potential involvement in the onset of atrial fibrillation (AF).
Arthur Boileve, Margaux Aize, Maximin Détrait, Laura Brard, Adrien Leboyer, Pierre‐Antoine Dupont, Alexandre Lebrun, Vladimir Saplacan, Christophe Simard, Fabien Brette, Frank Lezoualc'h, Laurent Sallé   +11 more
wiley   +1 more source