Results 101 to 110 of about 33,391 (242)

Population Pharmacokinetics of Ticagrelor during Veno‐Arterial ECMO in Acute Coronary Syndrome: Model‐Informed Dosing Simulations

Clinical Pharmacology &Therapeutics, Volume 120, Issue 1, Page 193-202, July 2026.
Although patients with acute coronary syndrome supported by veno‐arterial extracorporeal membrane oxygenation (VA‐ECMO) have a high risk of thrombosis and bleeding, antiplatelet pharmacology in this setting is not well defined. This prospective observational study investigated the population pharmacokinetics of ticagrelor and its active metabolite AR ...
Soyoung Kang, Kyoung Lok Min, Seungwon Yang, Jongsung Hahn, Dasohm Kim, Byung Hak Jin, Soon Uk Chae, Soo Kyung Bae, Jin Wi, Min Jung Chang   +9 more
wiley   +1 more source

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

Therapeutic Apheresis and Dialysis, Volume 30, Issue 3, Page 389-396, June 2026.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda, Tomohiro Saito, Masahide Mizobuchi, Tomoki Shimomura, Saki Kawamori, Mitsuru Kawanishi, Natsuko Hattori, Jo Sugiyama, Satoshi Tsubata, Hanami Horiguchi, Kazuki Abe, Nao Iida, Yuki Kajio, Nao Oguro, Ryo Yanai, Hirokazu Honda   +15 more
wiley   +1 more source

ECMO Support in Paraneoplastic Pemphigus With Respiratory Failure: A Case Report With Immune Cell Monitoring

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Paraneoplastic pemphigus (PNP) is a life‐threatening autoimmune blistering disease with a mortality rate of 70%–90%, driven largely by respiratory complications such as bronchiolitis obliterans. Managing respiratory failure in these patients remains exceptionally difficult.
Lu Li, Danxia Chen, Linzi Jin, Qinqin Shu, Juan He, Yan Li   +5 more
wiley   +1 more source

Model of extracorporeal circulation [PDF]

, 2018
Model mimotělního oběhu Mimotělní oběh je komplexní forma podpory životních funkcí pacienta během náročných kardiochirurgických operací, která nahrazuje funkci srdce a plic.
Ličková Vanda
core  

Clinical Profiles and Therapeutic Interventions in Occult Paraquat Poisoning: A Comparative Report of Two Cases

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Delayed diagnosis invariably worsens outcomes in occult paraquat poisoning regardless of exposure route. Implement early urinary screening for suspected cases. Tailor antioxidant and anti‐fibrotic timing to toxicokinetic patterns to mitigate irreversible pulmonary damage.
Minhong Zhao, Shuai Zhou, Ying Zhang, Eryan Yuan, Min Peng, Ying Gao   +5 more
wiley   +1 more source

Serum lactate/albumin ratio at hospital arrival and neurological outcomes in patients who received targeted temperature management after out‐of‐hospital cardiac arrest: A nationwide, multicenter, observational study

Hong Kong Journal of Emergency Medicine, Volume 33, Issue 3, June 2026.
Abstract Background A lower serum lactate/albumin ratio has been linked to favorable outcomes in critically ill patients. Objective We investigated whether the serum lactate/albumin ratio could predict the likelihood of benefiting from targeted temperature management (TTM) after out‐of‐hospital cardiac arrest (OHCA). Methods Using a nationwide Japanese
Tetsuro Nishimura, Toshinari Kawama, Toshihiro Hatakeyama, Takashi Sano, Koki Nakada, Tasuku Matsuyama, Takeyuki Kiguchi, Tetsuhisa Kitamura, Benjamin Worth Berg, Hisao Matsushima   +9 more
wiley   +1 more source

Retrospective Evaluation of Dual Specialty Ports in Therapeutic Apheresis

Journal of Clinical Apheresis, Volume 41, Issue 3, June 2026.
ABSTRACT Dual specialty ports were evaluated for safety and efficacy in therapeutic apheresis by analyzing outcomes across 97 port placement events in 88 patients, focusing on two configurations: dual Bard PowerFlow (BP2) and a combination of Bard PowerFlow with AngioDynamics SmartPort (BP + AD).
Mugtaba Swar‐Eldahab, Barnabas Obeng‐Gyasi, Paul Haste, Matthew Krosin   +3 more
wiley   +1 more source

Extracorporeal Circulation Causes Release of Neutrophil Gelatinase-Associated Lipocalin (NGAL)

Mediators of Inflammation, 1999
Extracorporeal circulation (ECC) used during cardiac surgery causes activation of several inflammatory systems. These events are not fully understood but are responsible for complications during the immediate postoperative period.
Per Jönsson, Marie-Louise Ståhl, Kjell Ohlsson   +2 more
doaj   +1 more source

Evaluation of Hemoadsorption Capacity of the CytoSorb Adsorber for Toxic Doses of Diclofenac and Meloxicam in Porcine Plasma

Journal of Clinical Apheresis, Volume 41, Issue 3, June 2026.
ABSTRACT The objective of this in vitro experimental was to determine the utility of hemoadsorption (HA) using the CytoSorb adsorber to remove meloxicam and diclofenac from porcine plasma. For this purpose 12 1‐L aliquots of porcine plasma, 6 units were spiked with 293 μg/mL (262–320 μg/mL) diclofenac and 6 with 42.8 μg/mL (41.4–44.7 μg/mL) meloxicam ...
Bettina Giani, René Dörfelt, Katrin Hartmann, Florian Sänger   +3 more
wiley   +1 more source

Effects of Extracorporeal Circulation and Heparin on the Phenotype of Platelet Surface Antigens following Heart Surgery

, 2000
In this prospective study, the time-dependent effects of extracorporeal circulation and heparin-mediated effects on platelet surface antigens in vitro were investigated using whole blood flow cytometry.
Barlage, Stefan, Birnbaum, Dietrich E., Rothe, Gregor, Schmitz, Gerd, Wahba, Alexander, Lodes, Heiko   +5 more
core   +1 more source