Results 111 to 120 of about 725,174 (193)
ABSTRACT Background Pediatric thromboembolism is increasingly encountered in critical care. Systemic thrombolysis with tissue plasminogen activator (tPA) facilitates vessel or valve patency, yet pediatric‐specific protocols remain undefined, and safety concerns persist. Objective To evaluate the efficacy and safety of a tailored, prolonged systemic tPA
Eran Shostak +5 more
wiley +1 more source
Successful cardiac and cerebral resuscitation with extracorporeal circulation and mild hypothermia
Extracorporeal circulation could be effective for cardiac resuscitation in patients who do not respond to ''Advanced cardiac life support'' (ACLS), but cannot guarantee brain survival.
Arnaoutoglou, H. +5 more
core
Given that PEEK chest wall implants induce shear force at the soft tissue‐implant interface due to respiratory motion in the early in vivo post‐implantation stage. We confirmed that this mechanical stimulus triggers the PIEZO1/ITGB1/YAP1 signalling axis in L929 and the STAT6/p‐STAT6 pathway in RAW264.7, which in turn mediates adhesion and migration of ...
Rou Huang +14 more
wiley +1 more source
Leukocyte and platelet activation during extracorporeal circulation
Extracorporeal circulation of blood has become a routine procedure in plasmapheresis, hemodialysis and cardiopulmonary bypass. Specifically in cardiopulmonary bypass, blood is exposed to a large material surface area, which induces an inflammatory ...
van Oeveren, W.
core +1 more source
ABSTRACT Perioperative anaphylaxis can cause sudden, catastrophic respiratory and cardiovascular collapse in high‐risk ESRD patients, even during regional anesthesia. Early recognition, prompt epinephrine administration, serum tryptase measurement, vigilant respiratory monitoring, and multidisciplinary preparedness—including ECMO capability—are ...
Madeline Dow +2 more
wiley +1 more source
Legend: SABV: Supra‐Aortic Branch Vessel; PND: permanent neurologic dysfunction; CKD: Chronic kidney disease; BCT: brachiocephalic trunk; LCCA: left common carotid artery. ABSTRACT Background Permanent neurologic dysfunction (PND) often complicates following surgery for acute type A aortic dissection (ATAAD) and is strongly correlated with unfavorable ...
Jian Chen +6 more
wiley +1 more source
Quercetin and Cardiovascular Health: An Evidence‐Based Review of Risk Factors and Treatments
Quercetin is a naturally occurring polyphenolic phytochemical distributed in fruits and vegetables. Quercetin, as a flavonoid, showed significant antioxidant capabilities and potential therapeutic effects on CVD risk factors. Quercetin reduces cardiac hypertrophy and apoptosis in cardiomyocytes by modulating critical signaling pathways.
Mohammad Reza Khazdair +2 more
wiley +1 more source
Extracorporeal Circulation: Effect of Long-Term (24-Hour) Circulation on Blood Components
Extracorporeal circulation damages blood and causes harmful side effects such as stroke and/or systemic inflammatory response in patients. Reactions of blood components to extracorporeal circulation include complement and inflammatory reactions ...
Solberg, Robert Glen
core
Improvements in micropore arterial line filter designs used for extracorporeal circulation are still needed because microbubbles larger than the rated pore sizes are being detected beyond the filter outlet.
Daniel P. Herbst
core +1 more source
Abstract Advanced mycosis fungoides (MF) and Sézary syndrome (SS) are the most aggressive forms of cutaneous T‐cell lymphoma and remain associated with a poor prognosis and heterogeneous therapeutic approaches. Recent advances, including targeted therapies and improved transplant strategies, have substantially expanded treatment options, highlighting ...
Francesco Onida +29 more
wiley +1 more source

