Results 111 to 120 of about 725,174 (193)

Safety and Effectiveness of a High‐Dose, Tailored Tissue Plasminogen Activator Therapy Protocol: A Joint Pediatric Hematology and Cardiac ICU Quality Improvement Initiative Analysis

open access: yesPediatric Blood &Cancer, Volume 73, Issue 11, November 2026.
ABSTRACT Background Pediatric thromboembolism is increasingly encountered in critical care. Systemic thrombolysis with tissue plasminogen activator (tPA) facilitates vessel or valve patency, yet pediatric‐specific protocols remain undefined, and safety concerns persist. Objective To evaluate the efficacy and safety of a tailored, prolonged systemic tPA
Eran Shostak   +5 more
wiley   +1 more source

Successful cardiac and cerebral resuscitation with extracorporeal circulation and mild hypothermia

open access: yes, 2006
Extracorporeal circulation could be effective for cardiac resuscitation in patients who do not respond to ''Advanced cardiac life support'' (ACLS), but cannot guarantee brain survival.
Arnaoutoglou, H.   +5 more
core  

Alternating Shear Force of Respiration Regulates Cell Interactions of Fibroblasts and Macrophages to Promote Soft Tissue Integration of Chest Wall Polyetheretherketone Implants

open access: yesAdvanced Science, Volume 13, Issue 62, 9 November 2026.
Given that PEEK chest wall implants induce shear force at the soft tissue‐implant interface due to respiratory motion in the early in vivo post‐implantation stage. We confirmed that this mechanical stimulus triggers the PIEZO1/ITGB1/YAP1 signalling axis in L929 and the STAT6/p‐STAT6 pathway in RAW264.7, which in turn mediates adhesion and migration of ...
Rou Huang   +14 more
wiley   +1 more source

Leukocyte and platelet activation during extracorporeal circulation

open access: yes, 1994
Extracorporeal circulation of blood has become a routine procedure in plasmapheresis, hemodialysis and cardiopulmonary bypass. Specifically in cardiopulmonary bypass, blood is exposed to a large material surface area, which induces an inflammatory ...
van Oeveren, W.
core   +1 more source

Perioperative Anaphylaxis and Respiratory Failure During AVF Surgery in an End‐Stage Renal Disease Patient

open access: yesClinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT Perioperative anaphylaxis can cause sudden, catastrophic respiratory and cardiovascular collapse in high‐risk ESRD patients, even during regional anesthesia. Early recognition, prompt epinephrine administration, serum tryptase measurement, vigilant respiratory monitoring, and multidisciplinary preparedness—including ECMO capability—are ...
Madeline Dow   +2 more
wiley   +1 more source

Nomogram for Postoperative Permanent Neurologic Dysfunction Following Acute Type A Aortic Dissection Surgery: A Multicentral Retrospective Study

open access: yesClinical Cardiology, Volume 49, Issue 11, November 2026.
Legend: SABV: Supra‐Aortic Branch Vessel; PND: permanent neurologic dysfunction; CKD: Chronic kidney disease; BCT: brachiocephalic trunk; LCCA: left common carotid artery. ABSTRACT Background Permanent neurologic dysfunction (PND) often complicates following surgery for acute type A aortic dissection (ATAAD) and is strongly correlated with unfavorable ...
Jian Chen   +6 more
wiley   +1 more source

Quercetin and Cardiovascular Health: An Evidence‐Based Review of Risk Factors and Treatments

open access: yesFood Science &Nutrition, Volume 14, Issue 11, November 2026.
Quercetin is a naturally occurring polyphenolic phytochemical distributed in fruits and vegetables. Quercetin, as a flavonoid, showed significant antioxidant capabilities and potential therapeutic effects on CVD risk factors. Quercetin reduces cardiac hypertrophy and apoptosis in cardiomyocytes by modulating critical signaling pathways.
Mohammad Reza Khazdair   +2 more
wiley   +1 more source

Extracorporeal Circulation: Effect of Long-Term (24-Hour) Circulation on Blood Components

open access: yes, 2010
Extracorporeal circulation damages blood and causes harmful side effects such as stroke and/or systemic inflammatory response in patients. Reactions of blood components to extracorporeal circulation include complement and inflammatory reactions ...
Solberg, Robert Glen
core  

The Effects of Pressure on Gases in Solution: Possible Insights to Improve Microbubble Filtration for Extracorporeal Circulation

open access: yes, 2013
Improvements in micropore arterial line filter designs used for extracorporeal circulation are still needed because microbubbles larger than the rated pore sizes are being detected beyond the filter outlet.
Daniel P. Herbst
core   +1 more source

Management of advanced mycosis fungoides and Sézary Syndrome: International Recommendations for systemic treatments and allogeneic hematopoietic cell transplantation from the European Hematology Association, the EORTC Cutaneous Lymphoma Tumours Group, the International Society for Cutaneous Lymphoma, and the Lymphoma Working Party of the EBMT

open access: yesHemaSphere, Volume 10, Issue 11, November 2026.
Abstract Advanced mycosis fungoides (MF) and Sézary syndrome (SS) are the most aggressive forms of cutaneous T‐cell lymphoma and remain associated with a poor prognosis and heterogeneous therapeutic approaches. Recent advances, including targeted therapies and improved transplant strategies, have substantially expanded treatment options, highlighting ...
Francesco Onida   +29 more
wiley   +1 more source

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