Results 131 to 140 of about 655,486 (246)

Microbubble‐Based Ultrasound Contrast Agents in Contrast‐Enhanced Ultrasonography for Managing Portal Hypertension in Cirrhosis

open access: yesPortal Hypertension &Cirrhosis, Volume 5, Issue 3, Page 260-268, September 2026.
As the hepatic venous pressure gradient (HVPG) remains the current gold standard for diagnosing portal hypertension in cirrhosis, its clinical application is limited by invasiveness, high cost, and restricted availability. Given the urgent need for noninvasive techniques to dynamically monitor portal vein pressure (PVP), contrast‐enhanced ...
Danping Huang   +5 more
wiley   +1 more source

Hemólise em circulação extracorpórea: estudo comparativo entre bomba de rolete e bomba centrífuga Hemolysis in extracorporeal circulation: a comparative study between roller and centrifugal pumps

open access: yesBrazilian Journal of Cardiovascular Surgery, 1989
O uso de bomba centrífuga como suporte circulatório para pacientes em choque cardiogênico, após a realização de cirurgia cardíaca e como suporte para pacientes com falência cardíaca que estão aguardando doação para transplante cardíaco, tem sido ...
Paulo M Pêgo-Fernandes   +8 more
doaj  

Integrating CRRT as a Virtual Organ Into Physiologically Based Pharmacokinetic Modeling to Optimize Antimicrobial Dosing in Septic Patients

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 9, September 2026.
Development and application of PBPK modeling integrating CRRT as a virtual organ to characterize antimicrobial pharmacokinetics and optimize dosing in septic patients. ABSTRACT Continuous renal replacement therapy (CRRT) extracorporeal drug removal, sepsis‐related pathophysiological alterations, and reduced pathogen susceptibility to antimicrobials can
Yuanming Xing   +7 more
wiley   +1 more source

The Changing Landscape of Hantavirus Infections: A Narrative Review of Epidemiology, Pathogenesis, and Countermeasures

open access: yesReviews in Medical Virology, Volume 36, Issue 5, September 2026.
ABSTRACT Hantaviruses are emerging zoonotic pathogens of increasing global public health significance. Their epidemiological landscape is rapidly changing due to ecological disruption, climate variability, urbanisation, and evolving human–animal interfaces.
Francesco De Maria   +5 more
wiley   +1 more source

Paediatric Index of Mortality 3 in Sweden: Validation and Recalibration to Improve Mortality Prediction in Paediatric Intensive Care

open access: yesActa Paediatrica, Volume 115, Issue 9, Page 2008-2017, September 2026.
ABSTRACT Aim In Sweden, critically ill children are admitted to one of four dedicated paediatric intensive care units (PICUs) or general intensive care units (ICUs), reflecting a partly centralised system. The Paediatric Index of Mortality 3 (PIM3) is a widely used risk stratification tool for predicting mortality in critically ill children. This study
Lars Engerström   +4 more
wiley   +1 more source

Posaconazole Target Attainment in Critically Ill Children: A 15‐Year Single‐Center Retrospective Analysis

open access: yesClinical and Translational Science, Volume 19, Issue 9, September 2026.
ABSTRACT Posaconazole is a triazole antifungal agent used for prophylaxis and treatment of invasive fungal diseases. Posaconazole has high inter‐individual variability in dose‐exposure relationship and benefits from therapeutic drug monitoring (TDM). Adult studies report particularly high rates of subtherapeutic exposure among intensive care unit (ICU)
Kathryn Pavia   +2 more
wiley   +1 more source

Progress in extracorporeal circulation

open access: yesThe Journal of Thoracic and Cardiovascular Surgery, 1977
openaire   +2 more sources

Mapping malignant T‐cell states and immune circuits in Sézary syndrome by single‐cell analysis

open access: yesJournal of the European Academy of Dermatology and Venereology, Volume 40, Issue 9, Page 1535-1549, September 2026.
Peripheral blood single‐cell RNA‐seq from leukaemic CTCL defined three malignant T‐cell programmes: MTC CM, MTC Reg and MTC E/EM, each with distinct features and candidate vulnerabilities. For example, inferred immune circuits highlighted actionable IL‐10/JAK–TYK2–STAT3 signalling, KIR–MHC I inhibitory interactions and myeloid/B‐cell inflammatory and ...
Beth A. Childs   +6 more
wiley   +1 more source

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