Results 1 to 10 of about 1,966 (247)

3D Membrane Microstructures for Increased Efficiency in Blood‐Gas Transfer [PDF]

Advanced Science
Treating severe lung diseases with extracorporeal membrane oxygenation (ECMO) is often accompanied by serious complications, restricting applicability and adversely affecting outcomes.
Kai P. Barbian, F. Neuhaus, L. T. Hirschwald, J. Linkhorst, M. Wessling, B. Wiegmann, J. M. Focke, U. Steinseifer, M. Neidlin, S. V. Jansen   +9 more
doaj   +2 more sources

Hybrid additive manufacturing-based assembly of sacrificial isomalt scaffolds and gas exchange membranes for microfluidic artificial lung development [PDF]

Microsystems & Nanoengineering
Preterm neonates are susceptible to respiratory distress syndrome (RDS) due to their underdeveloped lungs and require mechanical ventilation. Microfluidic blood oxygenators (MBOs) are a suitable alternative due to their small priming volume and their ...
Anand Sojan, Gerhard Fusch, Shahad Amin, Niels Rochow, Christoph Fusch, Ponnambalam Ravi Selvaganapathy   +5 more
doaj   +2 more sources

Oxygenator-related gaseous microemboli and postoperative delirium after on-pump coronary artery bypass grafting: a prospective cohort study [PDF]

BMC Anesthesiology
Background The increasing preference for off-pump coronary artery bypass grafting (CABG) reflects efforts to reduce complications associated with cardiopulmonary bypass (CPB).
Vladimir Tutuš, Milica Paunović, Slavko Kulić, Nina Rajovic, Nataša Milić, Vukašin Popović, Miloš Matković, Nemanja Aleksić, Radmila Karan, Jovana Stanisavljević, Svetozar Putnik, Danijela Trifunović Zamaklar, Dejan Marković   +12 more
doaj   +2 more sources

A Deep Reinforcement Learning-Optimized Blood Flow Profile for Enhanced Oxygenation Efficiency in Membrane Oxygenators [PDF]

Membranes
The membrane oxygenator serves as the core component of extracorporeal life support systems, and its gas exchange efficiency critically influences clinical outcomes. However, gas transfer is predominantly limited by the diffusion barrier within the blood-
Junwen Yu, Yuan Liu, Huaiyuan Guo, Qingyang Cheng, Junlong Meng, Ming Yang   +5 more
doaj   +2 more sources

Characterization of PEG-Modified Composite Membranes for Microfluidic Oxygenator Applications [PDF]

Micromachines
Microfluidic oxygenators promise to advance extracorporeal membrane oxygenation (ECMO) devices with enhanced hemodynamics and low prime volume. We are developing a silicon-based membrane oxygenator that will offer improved gas transfer and fluid flow ...
Nicholas C. Higgins, David G. Blauvelt, Shuvo Roy   +2 more
doaj   +2 more sources

A Validated CFD Model for Gas Exchange in Hollow Fiber Membrane Oxygenators: Incorporating the Bohr and Haldane Effects [PDF]

Membranes
Chronic respiratory diseases claim nearly four million lives annually, making them the third leading cause of death worldwide. Extracorporeal membrane oxygenation (ECMO) is often the last line of support for patients with severe lung failure.
Seyyed Hossein Monsefi Estakhrposhti, Jingjing Xu, Margit Gföhler, Michael Harasek   +3 more
doaj   +2 more sources

Tailored 3D Lattice Microstructures for Enhanced Functionality in Blood‐Gas Exchange [PDF]

Advanced Science
Current membrane oxygenators for extracorporeal life support (ECLS) are facing their limits regarding gas exchange efficiency and long‐term stability. One aspect adding to these limitations is inhomogeneous blood flow distribution inside the oxygenator's
Kai P. Barbian, Teresa Lemainque, Ina Grunden, Roman Iwa, Bettina Wiegmann, John Linkhorst, Matthias Wessling, Jan Heyer, Ulrich Steinseifer, Michael Neidlin, Sebastian V. Jansen   +10 more
doaj   +2 more sources

Evaluation of Integrated Arterial Filter Oxygenator vs. External Arterial Filters on Clinical Outcomes and Neurocognitive Function in Pediatric Cardiac Surgery: A Prospective Randomized Controlled Trial (RCT) [PDF]

Health Science Reports
Background and Aims Innovative advancements in cardiopulmonary bypass (CPB) configurations, such as surface coating, blood filtration, and miniaturization, aim to reduce gaseous microemboli (GME) that contribute to embolic organ damage, particularly ...
Vishal Vinayak Bhende, Mathangi Krishnakumar, Dushyantkumar Mukundbhai Parmar, Arunkumar Ghanshyambhai Rudakiya, Tanishq Shashikant Sharma, Amit Kumar, Paresh Dilip Nerurkar, Saptak Piyush Mankad, Mamta Roshan Patel   +8 more
doaj   +2 more sources

Prolonged ECMO support in a pediatric patient with complex cardiac conditions during wartime in Kyiv, Ukraine [PDF]

The Journal of ExtraCorporeal Technology
Background: In the conflict-affected setting of Kyiv, Ukraine, managing complex medical interventions presents significant challenges, especially for critically ill pediatric patients.
Rusnak Daniel, Condello Ignazio, Dohtiar Valerii, Varbanets Serhii, Alieksieieva Kristina, Luhovkin Serhii, Palokha Vladyslav, Zhoha Vadym, Bukhnei Neonila, Krashevska Lesia, Kutsenko Olha, Kupina Nataliia, Vnukov Oleksii   +12 more
doaj   +2 more sources

What Are the Best Biocompatible Materials for Extracorporeal Membrane Oxygenation [PDF]

Journal of Functional Biomaterials
Extracorporeal membrane oxygenation (ECMO) is a crucial life support therapy for patients with severe cardiac and respiratory failure. However, the complications associated with venoarterial ECMO (VA-ECMO), including thrombus formation, bleeding, and ...
Junya Hagiwara, Jeffrey D. DellaVolpe, Yuichi Matsuzaki   +2 more
doaj   +2 more sources