Results 51 to 60 of about 64,010 (305)

Stimuli‐Responsive Supramolecular Biomaterials for Cancer Theranostics

Advanced Science, EarlyView.
The ultimate goal of cancer theranostics is to get imaging agents and therapeutic cargo to tumor sites when and where they are required. “Smart” systems should be developed. This review discusses the characteristics of physiological stimuli, types and action modes of external stimuli, construction approaches and working principles, as well as ...
Wenting Hu, Binglin Ye, Guocan Yu, Feihe Huang, Zhengwei Mao   +4 more
wiley   +1 more source

Successful Extracorporeal Life Support for Life-threatening Hypercapnia with Bronchiolitis Obliterans after Allogeneic Hematopoietic Stem Cell Transplantation [PDF]

, 2011
Bronchiolitis obliterans (BO) is a disease with a poor prognosis, and a key factor that limits long-term survival after allogeneic hematopoietic stem cell transplantation (HSCT).
Ichiba, Shingo, Kanehiro, Arihiko, Maeda, Yoshinobu, Miyahara, Nobuaki, Murakami, Toshi, Nagano, Osamu, Ochi, Nobuaki, Tanimoto, Mitsune, Tanimoto, Yasushi, Terado, Michihisa, Ujike, Yoshihito, Waseda, Koichi   +11 more
core   +1 more source

Early Radial Extracorporeal Shockwave Stimulation on Proximal Tibial Circular Osteotomy Site Enhanced Heterotopic Skin Wound Healing via Small Extracellular Vesicles

Advanced Science, EarlyView.
A schematic diagram of the mechanism where small extracellular vesicles mediate the enhancement of heterotopic wound healing by radial extracorporeal shockwave stimulation at a proximal tibial osteotomy site. ABSTRACT Wound healing represents a complex biological process necessitating innovative therapeutic approaches, particularly for chronic wounds ...
Xiaoping Xie, Songqi Bi, Bang Su, Rongqi Zhou, Xudong Li, Zhixing Yan, Xiaoyang Zhou, Fanxu Wang, Tiecheng Yu   +8 more
wiley   +1 more source

Exploring using HBsAg to predict interferon treatment course to achieve clinical cure in chronic hepatitis B patients: a clinical study

Frontiers in Immunology
ObjectiveAlthough pegylated interferon α-2b (PEG-IFN α-2b) therapy for chronic hepatitis B has received increasing attention, determining the optimal treatment course remains challenging.
Fei Yan, Fei Tang, Jing Chen, YiCheng Lin, XinYu Chen, Qin Du, WeiLi Yin, Jing Liang, Lei Liu, Fang Wang, BaiGuo Xu, Qing Ye, HuiLing Xiang   +12 more
doaj   +1 more source

Primary hepatic squamous cell carcinoma: case report and systematic review of the literature

Frontiers in Oncology, 2023
Primary hepatic squamous cell carcinoma (SCC) is extremely rare, and only a few dozen cases have been reported to date. It can barely be diagnosed before histopathological examination, which necessitates the exclusion of metastatic tumors.
Lin Zhao, Lin Zhao, Lin Zhao, Yan Zhou, Yan Zhou, Yan Zhou, Jianmin Ding, Jianmin Ding, Jianmin Ding, Zhengyi Qin, Zhengyi Qin, Zhengyi Qin, Hongyu Zhou, Hongyu Zhou, Hongyu Zhou, Xiang Jing, Xiang Jing, Xiang Jing   +17 more
doaj   +1 more source

Traceless Regulation of Genetic Circuitry

Advanced Science, EarlyView.
Energy‐based, as opposed to molecular, control offers unprecedented improvements in key circuit parameters. This review summarizes the fundamentals of such traceless switches, categorizes them by trigger modalities, and compares and contrasts distinct advantages as well as shortcomings of each kind.
Gokberk Unal, Martin Fussenegger
wiley   +1 more source

Analysis of factors associated with the initiation of renal replacement therapy in patients on veno-arterial extracorporeal membrane oxygenation: a case–control study

BMC Nephrology
Background Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is a therapeutic strategy for refractory cardiogenic shock. However, it is associated with a high risk of complications, including acute kidney injury (AKI), which increases the need ...
Michel Perez-Garzon, Ana Castillo-Castillo, Maria Ferro-Peñuela, Claudia Poveda-Henao, Mario Mercado-Diaz, Henry Robayo-Amortegui   +5 more
doaj   +1 more source

Endogenous Amplification of Apoptosis via p53 Regulation using a Cascade Nanocatalytic Medicine

Advanced Science, EarlyView.
An engineered MOF nanomedicine (MAL) triggers cascade nanocatalysis in tumors, converting H2O2 and L‐Arg into cytotoxic peroxynitrite. This induces DNA damage, activates the p53 pathway, and amplifies mitochondrial apoptosis via the BAX/Bcl‐2/Caspase‐3 axis, effectively inhibiting colorectal cancer growth with high biocompatibility.
Tan Wu, Xiaoyue Xu, Dan Xu, Hui Zhang, Nan Wang, Yang Yang, Qian Chen, Shunjie Chen, Cheng Li   +8 more
wiley   +1 more source

Enhanced antitumor efficacy through microwave ablation combined with a dendritic cell-derived exosome vaccine in hepatocellular carcinoma

International Journal of Hyperthermia, 2020
Aim To investigate the antitumor efficacy of microwave ablation combined with dendritic cell-derived exosomes (Dex) or dendritic cells (DC) in treating hepatocellular carcinoma using a tumor-bearing mouse model.
Xinyu Zhong, Yan Zhou, Yuting Cao, Jianmin Ding, Peng Wang, Ying Luo, Hui Liu, Zhengyan Zhu, Xiang Jing   +8 more
doaj   +1 more source

The Extracorporeal Life Support Organization Maastricht Treaty for Nomenclature in Extracorporeal Life Support. A Position Paper of the Extracorporeal Life Support Organization [PDF]

American Journal of Respiratory and Critical Care Medicine, 2018
Extracorporeal life support (ECLS) was developed more than 50 years ago, initially with venoarterial and subsequently with venovenous configurations. As the technique of ECLS significantly improved and newer skills developed, complexity in terminology and advances in cannula design led to some misunderstanding of and inconsistency in definitions, both ...
Steven A. Conrad, L. Mikael Broman, Fabio S. Taccone, Roberto Lorusso, Maximilian V. Malfertheiner, Federico Pappalardo, Matteo Di Nardo, Mirko Belliato, Lorenzo Grazioli, Ryan P. Barbaro, D. Michael McMullan, Vincent Pellegrino, Daniel Brodie, Melania M. Bembea, Eddy Fan, Malaika Mendonca, Rodrigo Diaz, Robert H. Bartlett   +17 more
openaire   +5 more sources