Results 131 to 140 of about 52,465 (262)

Impact of Rapid Exome Sequencing on Pediatric Patients With Cardiomyopathy and Acute Heart Failure

open access: yesAmerican Journal of Medical Genetics Part A, Volume 200, Issue 6, Page 1222-1230, June 2026.
ABSTRACT Few studies describe the impact of rapid exome sequencing (ES) on pediatric cardiomyopathy in urgent clinical settings. Here, we retrospectively report the impact of rapid singleton ES in pediatric patients presented with acute heart failure and isolated cardiomyopathy or myocarditis, between 2021 and 2023 at a single tertiary care center.
Tameemi Abdalla Moady   +10 more
wiley   +1 more source

Pediatric Therapeutic Plasma Exchange: Characterization of Practice, Epidemiology, and Safety Profile at a Children's Hospital in the United States

open access: yesJournal of Clinical Apheresis, Volume 41, Issue 3, June 2026.
ABSTRACT There is a need to better understand the indications and safety profiles for therapeutic plasma exchange (TPE) in children. We aimed to assess pediatric TPE practice at a large academic center by retrospective chart review from 2011 to 2022. Patient demographics and clinical information including American Society for Apheresis (ASFA) category ...
Benjamin C. Lee   +4 more
wiley   +1 more source

Evaluating Modified Early Warning Score Compliance to Minimize Unnecessary Intensive Care Unit Admissions: A Descriptive Cross‐Sectional Needs Assessment at a University Teaching Tertiary Care Centre to Inform Quality Improvement Implementation

open access: yesJournal of Evaluation in Clinical Practice, Volume 32, Issue 4, June 2026.
ABSTRACT Background Intensive Care Unit (ICU) resources are scarce in low‐ and middle‐income countries (LMICs), with a median of 0.7 beds per 100,000 population. The Modified Early Warning Score (MEWS) aids early identification of clinical deterioration and supports standardized escalation and ICU triage decisions to optimize critical‐care resource use.
Mazhar Khalil   +15 more
wiley   +1 more source

Case Report: VV-ECMO as a bridge to recovery from ACE inhibitor induced post-obstructive negative pressure pulmonary edema

open access: yesFrontiers in Medicine
The indications for extracorporeal membrane oxygenation (ECMO) are becoming increasingly widespread nowadays. This case report describes the unique presentation of an adult patient with a combination of two rare complications: life-threatening angioedema
Darja Smirnova   +9 more
doaj   +1 more source

Pharmacokinetics of dolutegravir, tenofovir and lamivudine during venous–venous extracorporeal membrane oxygenation (VV‐ECMO): A case report

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 5, Page 1487-1492, May 2026.
While providing potentially life‐saving cardiorespiratory support for critically ill patients, extracorporeal membrane oxygenation (ECMO) may detrimentally affect pharmacokinetic (PK) performance and concurrent drug efficacy and safety. We describe a patient with Pneumocystis jirovecii pneumonia (PJP) in the context of acquired immunodeficiency ...
Tom C. Zwart   +7 more
wiley   +1 more source

A Case Series of Sudden Death in Children Aged 12 Months to 4 Years From LPIN1 Deficiency and PPA2 Deficiency in Queensland

open access: yes
Journal of Paediatrics and Child Health, EarlyView.
Sophie Manoy   +11 more
wiley   +1 more source

Giant Mediastinal Teratoma in a Child: A Case Report With a Brief Review of the Literature

open access: yesClinical Case Reports, Volume 14, Issue 5, May 2026.
Contrast‐enhanced axial chest CT showing a large, well‐circumscribed mediastinal mass measuring approximately 15.9 × 14.1 cm (maximum axial dimensions). The lesion is predominantly of fluid attenuation, occupies nearly the entire left hemithorax, and produces marked rightward deviation of the mediastinum, compression of the contralateral lung ...
Urías Hernandez Lopez   +5 more
wiley   +1 more source

Two Cases of Kounis Syndrome Caused by Contrast Medium: Early Extracorporeal Membrane Oxygenation

open access: yesClinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT In cardiology, Kounis syndrome (KS), also known as allergic angina or myocardial infarction, is often overlooked in emergencies. Its pathophysiology differs from that of allergic reactions such as anaphylaxis, making differentiation essential.
Kiichi Yano   +5 more
wiley   +1 more source

Anesthetic Management of Acute Right Tension Pneumothorax in a Child With Left Main Bronchial Foreign Body: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT In children with complete unilateral main bronchial obstruction from foreign body aspiration, positive pressure ventilation may overdistend the contralateral ventilated lung, leading to barotrauma and tension pneumothorax. Sudden hypoxemia and hypotension should prompt rapid clinical assessment, including lung ultrasound, and immediate ...
Kun Yue, Xuewu Ji, Yingying Sun, Yin Xia
wiley   +1 more source

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