Results 71 to 80 of about 35,632 (212)

Refining the treatment of immune checkpoint inhibitor–associated myocarditis: Challenges, innovations and rechallenge considerations

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitor (ICI)‐associated myocarditis has emerged as a severe and clinically complex immune‐related toxicity that poses significant challenges for therapeutic decision‐making in routine cardio‐oncological care. High‐dose corticosteroids remain the first‐line therapy, yet their timing, dosage and tapering require careful clinical ...
Raluca I. Mincu, Lisa Zimmer, Dimitra Vlachopoulou, Elias Haj‐Yehia, Julia Hoffmann, Lars Michel, Elisabeth Livingstone, Dirk Schadendorf, Alpaslan Tasdogan, Matthias Totzeck, Tienush Rassaf   +10 more
wiley   +1 more source

“Decompression illness” on extracorporeal membrane oxygenation

Journal of Cardiothoracic Surgery
Background Extracorporeal membrane oxygenation (ECMO) is increasingly being used for critically ill patients with cardiopulmonary failure. Air in the ECMO circuit is an emergency, a rare but fatal complication.
Jiannan Hu, Huijing zhao, BingBing Bian, Renfei San, Peng Yang, Yongpo Jiang   +5 more
doaj   +1 more source

Extracorporeal membrane oxygenation (ECMO) – A lifesaving modality for treatment of pheochromocytoma-induced inverted Takotsubo-like cardiomyopathy

Egyptian Journal of Critical Care Medicine, 2018
Pheochromocytoma is a rare neuroendocrine tumors which overproduce catecholamines and arise from the adrenal gland or extra-adrenal chromaffin cells of the sympathetic and parasympathetic ganglia.
Tarek Abdel Aziz, Mohamed Fayaz Khazi, Yehia Karaly, Kamal Al Tahmody, Fariborz Bagheri, Ahmed Khalaf, Yasir Amin, Ashraf El Houfi, Rashid Nadeem, Hassan Hotait, Obaid Al Jasim   +10 more
doaj   +1 more source

Progressive Pulmonary Alveolar Proteinosis Diagnosis Masking Pneumonic Lung Carcinoma: Anchoring Bias in Critical Care

Cytopathology, EarlyView.
A presumed case of pulmonary alveolar proteinosis with clinical deterioration was ultimately identified at autopsy as pneumonic‐type pleomorphic carcinoma. This case highlights the diagnostic overlap between diffuse lung diseases and the risk of anchoring bias in critically ill patients.
Dakota Wheeler, Rhaya Murray, Teklu Legesse, Hector Mesa   +3 more
wiley   +1 more source

ECMO to CPB: A single circuit approach

The Journal of ExtraCorporeal Technology
Background: Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) and cardiopulmonary bypass (CPB) are used during pediatric heart surgery to provide cardiopulmonary support to patients as they undergo and recover from surgical procedures.
Zalfa Jeffrey, Duncan Daniel, Kerins Paul   +2 more
doaj   +1 more source

Phase IIB, Randomized, Double‐Blind, Placebo‐Controlled Clinical Trial of Intravenous Defibrotide for the Prevention and Treatment of Respiratory Distress and Cytokine Release Syndrome in COVID‐19

European Journal of Haematology, EarlyView.
ABSTRACT Introduction Endothelial dysfunction is key in COVID‐19 pathogenesis. This randomized, double‐blind phase IIb trial investigated continuous intravenous infusion of defibrotide in patients hospitalized with SARS‐CoV‐2 infection and respiratory failure.
Ruben Jara Rubio, Antonio José Martinez‐Mellado, Jonathan Kiwitt‐Cárdenas, José G. Clavel, Bartolomé García‐Perez, Pedro Castro, Maribel Diaz‐Ricart, Andrés Carrillo‐Alcaraz, Amparo López‐Bernús, Enrique Bernal Morell, Aychel Roura, Sonia Marín, Francisco‐José Ruiz‐López, Elena Solana‐Martinez, Domingo Martinez‐Baño, Carlos L. Albacete Moreno, Enriqueta Andreu Soler, Adrián Tellez Santoyo, Sara Fernández Méndez, Jose A. Noguera Velasco, Iria Cebreiros Lopez, Andrés Parrilla, Alberto Espuny‐Miró, David García‐Bernal, Miguel Blanquer, Andrés Sánchez‐Salinas, Francisca Iniesta, Cristina Hernandez Garcia, Manuel Muro, Alfredo Minguela Puras, Antonio Moreno‐Docón, Alberto M. Torres‐Cantero, Maria Munoz Garcia, Manuel Serrano, Massimo Iacobelli, Carmelo Carlo‐Stella, Lee‐Jen Wei, Paul G. Richardson, José M. Moraleda   +38 more
wiley   +1 more source

Physiotherapy for ECMO patients

Egyptian Journal of Critical Care Medicine, 2018
Physiotherapy is part of the overall care in an interdisciplinary intensive care unit. Patients on extracorporeal membrane oxygenation (ECMO) were previously deemed to be too unstable to mobilise. Safety is of paramount importance as these patients often
Marlice van Dyk
doaj   +1 more source

Assessment of Thrombin Generation in Pediatric Patients on Extracorporeal Life Support: Impact of Bivalirudin and Other Anticoagulants

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Bivalirudin is an alternative anticoagulant to heparin and is widely used in pediatric extracorporeal life support (ECLS). Its activity is monitored using activated partial thromboplastin time (aPTT) and/or more specific tests such as plasma‐diluted thrombin time (dTT).
Vadim Kostousov, Karen Bruzdoski, Amir Navaei, Jun Teruya   +3 more
wiley   +1 more source

Extracorporeal Membrane Oxygenation (ECMO) Cardiopulmonary Support in Infancy

The Journal of ExtraCorporeal Technology, 1979
We have used prolonged extracorporeal membrane oxygenation (ECMO) in the treatment of 13 moribund infants (including 9 neonates), with 4 survivors (3 neonates). Successfully treated cases include post-operative cardiac failure, infant respiratory distress syndrome, massive meconium aspiration, and persistent fetal circulation.
R H, Bartlett, A B, Gazzaniga, M R, Jefferies, R F, Huxtable, N J, Haiduc, S W, Fong   +5 more
openaire   +2 more sources

Negotiated Ventilation: Conceptualising Interprofessional Decision Work in Intensive Care—An Ethnographic Study

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim To conceptualise how ventilation‐related decisions are accomplished as interprofessional work in intensive care practice, moving beyond approaches that treat decision‐making as discrete events. Design Ethnography. Methods Data were generated through 97 h of participant observation and 17 episodic interviews with nurses (n = 12) and ...
Andreas Küpper, Marcel Schmucker, Laura Hahn, Astrid Elsbernd, Simon Kitto, Cornelia Mahler   +5 more
wiley   +1 more source