Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Improving Peach Fruit Yield and Quality Using Foliar Application of Nano Chelated Zinc and Seaweed Extract (<i>Spirulina platensis</i>): A Multivariate Analysis Approach. [PDF]
Dawood AI +3 more
europepmc +1 more source
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Safety and efficacy of a feed additive consisting of an extract from the dried leaves of <i>Hedera helix</i> L. (common ivy extract) and thymol for all animal species and categories except poultry, ornamental birds and all aquatic animal species (FEFANA asbl). [PDF]
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +22 more
europepmc +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Xanthine Oxidase Inhibitory Potential of <i>Achillea santolina</i> Methanolic Extract with ROS Modulation in HepG2 Cells. [PDF]
Althaher AR, Awadallah MW, Qattoum MN.
europepmc +1 more source
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source
Comparative <i>in vitro</i> antibacterial activity of herbal extracts from <i>Piper betle</i> L., <i>Bauhinia scandens</i> L. and <i>Chromolaena odorata</i> against <i>Staphylococcus aureus</i>, <i>Escherichia coli</i> and <i>Pseudomonas aeruginosa</i>. [PDF]
Kong S +7 more
europepmc +1 more source
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source

