Results 131 to 140 of about 6,935,481 (374)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Selective and Efficient Biomacromolecular Extraction of Rare-Earth Elements using Lanmodulin

, 2020
Gauthier J.‐P. Deblonde, Joseph A. Mattocks, Dan Park, David W. Reed, Joseph A. Cotruvo, Yongqin Jiao   +5 more
openalex   +2 more sources

A New Framework for Automatic Airports Extraction from SAR Images Using Multi-Level Dual Attention Mechanism [PDF]

, 2020
Lifu Chen, Siyu Tan, Zhouhao Pan, Xing Jin, Zhihui Yuan, Xuemin Xing, Peng Zhang   +6 more
openalex   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Optimization and characterization of silver nanoparticle-modified luffa for the adsorption of ketoprofen and reactive yellow 15 from aqueous solutions

Scientific Reports
In the current work, luffa was modified with silver nanoparticles to prepare LF/AgNPs adsorbent for the elimination of ketoprofen and reactive yellow 15 (RY15) from aqueous media.
Soheil Tavassoli, Setareh Cheraghi, Pardis Etemadifar, Afsaneh Mollahosseini, Shirin joodaki, Niloofar Sedighi   +5 more
doaj   +1 more source

Differences in change of post‐operative antioxidant levels between laser‐assisted lenticule extraction and femtosecond laser in situ keratomileusis [PDF]

, 2023
Hung‐Chi Chen, Shun‐Fa Yang, Chia‐Yi Lee, Yi‐Jen Hsueh, Jing‐Yang Huang, Chao‐Kai Chang   +5 more
openalex   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Facial assessment methods for inhibiting glycation and aging effects and the correlation between glycation and aging parameters

Scientific Reports
This study aimed to develop in vivo methods for assessing facial anti-glycation and anti-aging effects and to investigate the link between glycation and aging signs.
Qin Zhang, Dangdang Cheng, Feifei Wang
doaj   +1 more source