Results 221 to 230 of about 5,388,909 (328)
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
From Biomass to Efficient Lipid Recovery: Choline-Based Ionic Liquids and Microwave Extraction of <i>Chlorella vulgaris</i>. [PDF]
Agostinho DAS +5 more
europepmc +1 more source
Multi-Scale Geospatial Object Detection Based on Shallow-Deep Feature Extraction [PDF]
Dalal AL-Alimi +5 more
openalex +1 more source
Protein O‐glycosylation in the Bacteroidota phylum
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns +2 more
wiley +1 more source
Optimization of Ultrasound-Assisted Methanolic Extraction of <i>Terminalia arjuna</i> Bark Using Response Surface Methodology and Characterization of the Extract. [PDF]
Tahir H +8 more
europepmc +1 more source
Corrected parabolic fitting for height extraction in confocal microscopy
Chen Cheng +5 more
openalex +1 more source
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić +3 more
wiley +1 more source
Balancing yield and stability: optimizing leaf pigment extraction to minimize chlorophyll degradation. [PDF]
Sitarek-Andrzejczyk M +3 more
europepmc +1 more source

