Results 41 to 50 of about 293,237 (309)

Automated LC-MS analysis and data extraction for high-throughput chemistry [PDF]

, 2023
J. S. Mason, Harry Wilders, David J. Fallon, Ross P. Thomas, Jacob T. Bush, Nicholas C. O. Tomkinson, Francesco Rianjongdee   +6 more
openalex   +3 more sources

Luffa–Ni/Al layered double hydroxide bio-nanocomposite for efficient ibuprofen removal from aqueous solution: Kinetic, equilibrium, thermodynamic studies and GEP modeling

Heliyon
Luffa is a robust, renewable biomaterial known for its low mass, high specific strength, and non-toxicity, making it ideal for composite development.
Soheil Tavassoli, Afsaneh Mollahosseini, Saeed Damiri, Mehrshad Samadi   +3 more
doaj   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Genotoxic effect of heavy metals on Astyanax lacustris in an urban stream

Heliyon, 2020
Uncontrolled urbanization growth contributes to the pollution of aquatic environments. Heavy metals released by domestic and industrial effluents can negatively affect aquatic organisms. This study aimed to evaluate the effect of environmental pollutants,
Emanoelle Pereira da Silva, Marcelino Benvindo-Souza, Carlos Filipe Camilo Cotrim, Andreya Gonçalves Costa Motta, Matheus Mendonça Lucena, Nelson Roberto Antoniosi Filho, Julião Pereira, Klebber Teodomiro Martins Formiga, Daniela Melo e Silva   +8 more
doaj   +1 more source

Identification of groundwater conditions in the recharge zone of regionally extended aquifer system with use of water chemistry and isotopes (Lwowek region, Poland)

Journal of Hydrology: Regional Studies, 2021
Study region: The studied recharge zone of regionally extended Quaternary aquifers - Lwówek region (Wielkpolska, Poland) is located in a region where Quaternary aquifers are the principal source of drinking water.
Krzysztof Dragon
doaj   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

FEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur, Brian Acquaviva, Baylee A. Smith, Nathan Walker, Isabella Walter, Matthew L. Wohlever   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

LC-HRMS Coupling to Feature-Based Molecular Networking to Efficiently Annotate Monoterpene Indole Alkaloids of Alstonia scholaris

Plants
Monoterpene indole alkaloids (MIAs) exhibit diverse structures and pharmacological effects. Annotating MIAs in herbal medicines remains challenging when using liquid chromatography combined with high-resolution mass spectrometry (LC-HRMS).
Ying-Jie He, Yan Qin, Xiao-Dong Luo
doaj   +1 more source

Vegetable Oils as Alternative Solvents for Green Oleo-Extraction, Purification and Formulation of Food and Natural Products

Molecules, 2017
Since solvents of petroleum origin are now strictly regulated worldwide, there is a growing demand for using greener, bio-based and renewable solvents for extraction, purification and formulation of natural and food products.
Edinson Yara-Varón, Ying Li, Mercè Balcells, Ramon Canela-Garayoa, Anne-Sylvie Fabiano-Tixier, Farid Chemat   +5 more
doaj   +1 more source