Results 61 to 70 of about 558,452 (194)

Extracting Crystal Chemistry from Amorphous Carbon Structures [PDF]

open access: yesChemPhysChem, 2017
AbstractCarbon allotropes have been explored intensively by ab initio crystal structure prediction, but such methods are limited by the large computational cost of the underlying density functional theory (DFT). Here we show that a novel class of machine‐learning‐based interatomic potentials can be used for random structure searching and readily ...
Volker L. Deringer   +2 more
openaire   +4 more sources

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

open access: yesFEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang   +2 more
wiley   +1 more source

Trace determination of linear alkylbenzene sulfonates: application in artificially polluted soil-carrots system [PDF]

open access: yes, 2009
Surfactants are widely used in household and industrial products. The risk of incorporation of linear alkylbenzene sulfonates (LAS)from biosolids, wastewater, and fertilizers land application to the food chain is being assessed at present by the European
Sablayrolles, Caroline   +3 more
core   +5 more sources

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Main Variables Affecting a Chemical-Enzymatic Method to Obtain Protein and Amino Acids from Resistant Microalgae [PDF]

open access: yes, 2019
he development of microalgae uses requires further investigation in cell disruption alternatives to reduce the costs associated to this processing stage. This study aimed to evaluate the main variables affecting an extraction method to obtain protein and
Bolívar Pérez, Jorge   +3 more
core   +2 more sources

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Development of solid-phase extraction and methylation procedures to analyse free fatty acids in lipid-rich plant materials [PDF]

open access: yes, 2008
The objective of the present work was to develop a solid-phase extraction-gas chromatography (SPE-GC) method to isolate and measure free fatty acids (FFA) in lipid-rich seeds for immediate use in our investigations on the non-orthodox storage behaviour ...
De Kochko, Alexandre   +3 more
core  

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

open access: yesFEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg   +2 more
wiley   +1 more source

Biodiesel via in situ wet microalgae biotransformation: Zwitter-type ionic liquid supported extraction and transesterification [PDF]

open access: yes, 2017
The production of biodiesel derived from microalgae is among the most forthcoming technologies that provide an ecologic alternative to fossil fuels.
Bauer, Gerald   +4 more
core   +2 more sources

AMINES AS EXTRACTANTS--SURVEY OF THE DESCRIPTIVE AND FUNDAMENTAL EXTRACTION CHEMISTRY [PDF]

open access: yes, 1963
Both the study and the use of extractions with highmolecular-weight amines (including quaternary ammoniums) in organic solution are increasing extensively. While equilibria have been measured in the extraction of an increasing range of acids and Aetal ions, a difficulty remains unresolved in that the amine concentration powerdependence of extraction ...
openaire   +3 more sources

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