Results 61 to 70 of about 407,586 (267)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Extracting Hadamard Coefficients from Green's Operators

open access: yes, 2023
This is the Author's Ph. D. thesis (with minor typo corrections), advised by Prof. Matthias Lesch and unofficially also advised by Dr. Koen van den Dungen.
openaire   +2 more sources

EFFECT OF DIFFERENT METHODS OF EXTRACTION ON OPTICAL PROPERTIES FOR DYE LANTANA CAMERA

open access: yesJournal of Kufa-Physics, 2019
This work focuses on the two methods of extraction for dye plant Lantana Camara (ethanol and water), thin film was synthesized from two solvents by spin coating method on glass substrates.
Fatima Hamid Malik   +1 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Heat Transfer Model for Traditional Chinese Medicine Extraction and Its Application in Laboratory and Industrial Equipment

open access: yesSeparations
A semi-empirical lumped parameter model for the extraction process of traditional Chinese medicine based on thermal equilibrium was established in this work. In this model, the effect of heat dissipation was considered.
Gelin Wu   +5 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Fast separation of Cu2+ and Ni2+ in sulfate solution by Lix984N extraction using a microchannel chip

open access: yesGreen Processing and Synthesis, 2018
A comparison study about the extraction and separation of Cu2+ and Ni2+ with Lix984N in a microchannel reactor and separating funnel has been conducted.
Xiao Biquan   +7 more
doaj   +1 more source

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