Results 81 to 90 of about 1,942,583 (286)

Optimizing design and stability of open pit slopes in Tolay coal mine, Ethiopia

Scientific Reports
Coal is a critical energy resource for global industries, and its extraction from open-pit mines requires effective slope stability management to ensure safe and efficient operations.
E. Alemayehu, E. T. Chala, N. Z. Jilo, Tiyasha Tiyasha, B. Moges   +4 more
semanticscholar   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

Integrated and improved YOLOv8 and triangulated network method for extracting indicators in open-pit mine mining areas

Gong-kuang zidonghua
The research on remote sensing imagery of open-pit mines based on deep learning has provided a direction for the rapid identification and extraction of open-pit mining areas.
LI Tianwen, LI Gongquan, LI Juntao
doaj   +1 more source

Temporal Interference Stimulation of Centromedian‐Parafascicular Complex in Disorders of Consciousness: A Pilot Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu, Changgeng Song, Dianwei Wu, Xiaoqian Niu, Jianmin Hao, Lijuan Liu, Xiaogang Kang, Wen Jiang   +7 more
wiley   +1 more source

Geomechanical Basis for Assessing Open-Pit Slope Stability in High-Altitude Gold Mining

Applied Sciences
The development of mining operations in high-altitude regions is associated with a number of geomechanical challenges caused by increased rock fracturing, adverse climatic conditions, and high seismic activity.
Farit Nizametdinov, R. Nizametdinov, D. Akhmatnurov, N. Zamaliyev, R. Mussin, N. Ganyukov, K. Skrzypkowski, W. Korzeniowski, J. Stasica, Zbigniew Rak   +9 more
semanticscholar   +1 more source

Clinical Impact of MGMT Promoter Methylation in IDH‐Mutant Gliomas: Influence of Threshold Selection and Clinical Confounding

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background The clinical relevance of MGMT promoter methylation in IDH‐mutant gliomas remains controversial in the era of molecular classification. We aimed to systematically evaluate its clinical relevance by integrating quantitative assessment, cutoff exploration, and adjustment for clinical confounding.
Haihui Jiang, Linxi Cao, Xiaodong Chen, Siqi Tong, Qinghui Zhu, Jun Yang, Song Lin, Yong Cui   +7 more
wiley   +1 more source

Social warfare for lithium extraction? Open-pit lithium mining, counterinsurgency tactics and enforcing green extractivism in northern Portugal

Energy Research & Social Science, 2023
A. Dunlap, Mariana Riquito
semanticscholar   +1 more source

Optimization of ore production scheduling strategy using NSGA-II-GRA in open-pit mining

Scientific Reports
To address the challenges posed by ore grade fluctuations, extraction cost variations, and market price instability in open-pit ore production strategies, an optimization model integrating a solution algorithm integrating dynamic simulation is proposed ...
Zhongqiang Chen, Ping Song, Run-Han Liu, Qi Wang, Yumeng Shen   +4 more
semanticscholar   +1 more source

Glucagon‐Like Peptide‐1 Receptor Agonists in Multiple Sclerosis: A Topical Narrative Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The glucagon‐like peptide‐1 (GLP‐1) receptor agonists (RAs) are a relatively new class of drugs that were initially approved by the US Food and Drug Administration to improve glycemic control in patients with type 2 diabetes mellitus and, subsequently, weight reduction in patients with obesity.
Audrey Y. Chang, Farrah J. Mateen
wiley   +1 more source

Research on Visual–Inertial Measurement Unit Fusion Simultaneous Localization and Mapping Algorithm for Complex Terrain in Open-Pit Mines

Sensors
As mining technology advances, intelligent robots in open-pit mining require precise localization and digital maps. Nonetheless, significant pitch variations, uneven highways, and rocky surfaces with minimal texture present substantial challenges to the ...
Yuanbin Xiao, Wubin Xu, Bing Li, Hanwen Zhang, Bo Xu, Weixin Zhou   +5 more
doaj   +1 more source