Results 191 to 200 of about 1,492 (259)

Simulation-Based Optimization over Discrete Spaces Using Projection to Continuous Latent Spaces. [PDF]

Ind Eng Chem Res
Hernández-Morales G, Cansino-Loeza B, Jiménez-Gutiérrez A, Zavala VM.   +3 more
europepmc   +1 more source

A Spatially Directed Microneedle Patch Enables Intratumoral Co‐Delivery of FOLFIRINOX, Surufatinib, and Anti‐PD‐1 for Chemo‐Immunotherapy of Pancreatic Ductal Adenocarcinoma

Advanced Science, EarlyView.
A double‐layered shell‐core microneedle patch is developed to co‐deliver FOLFIRINOX, surufatinib, and anti‐PD‐1 for localized chemo‐immunotherapy of PDAC. This strategy achieves sustained tumor suppression, reduces metastasis, and reprograms the TME by enhancing CD8+ T‐cell infiltration and inhibiting Tregs and M2 macrophages infiltration, while ...
Tingting Kong, Ximo Xu, Xiao Zhang, Chuntao Wu, Zhengjun Qiu, Beiyuan Hu, Zihao Qi, Qiang Tian, Yuqin Yang, Hanguang Dong, Fei Wu, Tuo Jin, Yan Zheng, Jiang Long   +13 more
wiley   +1 more source

Molecular Chain Elongation Mechanism for n-Caproate Biosynthesis by Megasphaera Hexanoica. [PDF]

Adv Sci (Weinh)
Jeon BS, Kim EJ, Seo H, Kim H, Shin S, Schlaiß C, Angenent LT, Kim KJ, Sang BI.   +8 more
europepmc   +1 more source

A Disulfide‐Sticker Strategy for Marine Adhesive Coatings: From Deciphering Self‐Assembly Mechanism to Functional Application in Hair Regeneration

Advanced Science, EarlyView.
A disulfide‐sticker strategy, coupled with Ca2+ coordination, drives the hierarchical self‐assembly of a recombinant scallop adhesive protein into fishnet‐like nanostructures, affording a coating with versatile wet adhesion and intrinsic antioxidant activity. This biocompatible coating markedly promotes hair regeneration by activating follicular niches,
Lulu Wang, Juan Yang, Xin Jiang, Zhanghui Zheng, Hongyu Wei, Na Li, Xiangqiang Chu, Weizhi Liu   +7 more
wiley   +1 more source

Wine Industry Waste as a Source of Bioactive Compounds for Drug Use. [PDF]

Int J Mol Sci
Mesta-Corral M, Ramirez-Guzman N, Aguillón-Gutiérrez D, Torres-León C, Aguirre-Joya J.   +4 more
europepmc   +1 more source

Functionalized Biomimetic Scaffolds for Human‐Derived Auditory Neural Circuit Construction

Advanced Science, EarlyView.
In Vitro Auditory Circuit Model. ABSTRACT Damage to auditory circuits results in sensorineural hearing loss. However, the scarcity of human inner ear tissue significantly hinders the development of therapies to preserve auditory function, creating a critical need for reliable in vitro models.
Pan Feng, Qian Zhu, Yusong Wang, Hao Rong, Xu Zhang, Fuchun Wang, Tianqi Yu, Wenxuan Wang, Jing Li, Lei Tian, Menghui Liao, Renjie Chai, Yangnan Hu   +12 more
wiley   +1 more source

Exploiting the Biorefinery Potential of Spent Mushroom Substrate: The Time to Do It Is Now. [PDF]

Molecules
Martín C, Xiong S, Zervakis GI.
europepmc   +1 more source

Influence of lactulose as a composition of organic-mineral feed additive on broiler chicken productivity, feed digestibility, and microbiome. [PDF]

Vet World
Sizova EA, Shoshin DE, Yausheva EV, Ivanishcheva AP, Nechitailo KS, Ryazantseva KV.   +5 more
europepmc   +1 more source

Seaweed Polysaccharides: A Rational Approach for Food Safety Studies. [PDF]

Mar Drugs
Cotas J, Lourenço M, Figueirinha A, Valado A, Pereira L.   +4 more
europepmc   +1 more source