Results 171 to 180 of about 1,492 (259)

Microbial-Based Agrochemicals: Cell-in and Cell-free Formulations, Application, and Production via Agricultural Byproducts for a Circular Economy. [PDF]

ACS Omega
Buttrós VH, Resende de Souza Castro C, D'Ávilla VA, Ribeiro NAS, Ribeiro LS, Baldez FLM, Chagas MLM, Dambroz C, Silva LI, E Bufalo TC, Dória J.   +10 more
europepmc   +1 more source

Introducing Borsantrazole: A Trifunctional Boron‐Based Pyrazole That Extends the Lifespan of Amyotrophic Lateral Sclerosis Mice

Advanced Science, EarlyView.
Herein we report a boron‐based pyrazole, (Borsantrazole ‐ a small molecule that selectively targets oxidative stress) that significantly increases survival, reduces weight loss, delays disease onset, and affects global protein changes in the SOD1‐G37R mouse model of ALS.
Nitesh Sanghai, Rhonda Kelley, Ying Lao, M. Immanuel Reyes Madlangsakay, Prasanta Paul, M. Alejandra Llanes‐Cuesta, Jun‐Feng Wang, René P. Zahedi, Jiming Kong, Geoffrey K. Tranmer   +9 more
wiley   +1 more source

Valorization of birch tops and branches containing mechanically inseparable wood and bark.

Green Chem
Ramazanova L, Tammekivi E, Kruve A, Samec JSM.   +3 more
europepmc   +1 more source

Butyric acid production from corn: economics of fermentative production of a novel biobased chemical. [PDF]

J Ind Microbiol Biotechnol
Qureshi N, Mishra S, Liu Z, Singh M, Hector RE, Ezeji TC, Ashby RD, Jackson MA, Singh V.   +8 more
europepmc   +1 more source

PFKFB4 Deubiquitination by USP10 Enhances Fumarate Metabolism to Orchestrate the KDM1A/Rad51 Axis and Confer Radioresistance in Lung Cancer

Advanced Science, EarlyView.
USP10 binds to and stabilizes PFKFB4, enhancing glycolytic ATP production, which activates the urea cycle and elevates fumarate. This inhibits histone demethylase KDM1A, leading to increased H3K4me1 enrichment at the Rad51 promoter and direct activation of Rad51 transcription, which confers lung cancer radioresistance. The PFKFB4 inhibitor 5MPN targets
Yunshang Chen, Zilong Wu, Yongqiang Yang, Ruoxin Fang, Huichan Xue, Rui Zhou, Gang Wu, Xiaohua Jie   +7 more
wiley   +1 more source

Optimizing the treatment and valorization of spent coffee grounds (SCGs) through the integration of sequential pretreatment steps, enzymatic hydrolysis, and selective fermentation. [PDF]

Food Chem X
Cho EJ, Lee WH, Lee YG, Van Ta Q, Kim HY, Bae HJ.   +5 more
europepmc   +1 more source

Microalgae Hybrid Biosystem for Enhanced Oral Delivery of Rifaximin in Hepatic Encephalopathy Treatment

Advanced Science, EarlyView.
The microalgae‐nanoparticle hybrid system with antibacterial activity can improve the oral delivery and therapeutic efficiency for hepatic encephalopathy treatment. Oral administration of the system can reduced systemic ammonia levels, enhanced intestinal barrier function, attenuated systemic and neuroinflammation, ameliorated cognitive impairments ...
Kaiyue Wang, Xueting Huang, Lingxiao Yang, Jin Liu, Lei Lei, Shaomin Zou, Kai Wang, Min Zhou, Zhe Tang   +8 more
wiley   +1 more source

Analysis of the economic viability and environmental impacts of a conceptual process model for the recovery of lactic acid from spent media in cultivated meat production. [PDF]

Biotechnol Prog
Wimble J, Ashizawa R, Swartz EW.
europepmc   +1 more source

A Generative Neuro‐Symbolic AI for Protein Sequence Design

Advanced Science, EarlyView.
We introduce EffieDes, a neuro‐symbolic framework coupling deep learning‐based fitness landscape parameterization with exact automated reasoning. Unlike greedy sampling, EffieDes identifies sequences that globally optimize fitness while satisfying intricate design constraints.
Marianne Defresne, Delphine Dessaux, Samuel Buchet, Lucie Barthe, Liza Ammar‐Khodja, Bessam Azizi, Valentin Durante, Gianluca Cioci, Simon de Givry, Alain Roussel, Luis F. Garcia‐Alles, Thomas Schiex, Sophie Barbe   +12 more
wiley   +1 more source

Biorefining spent substrates of shiitake (<i>Lentinula edodes</i>) and oyster mushroom (<i>Pleurotus ostreatus</i>): enzymatic saccharification of cellulose and xylan, with lignin recovery from residues. [PDF]

Bioengineered
Klausen SJ, Romero-Soto LA, Liaqat A, Dehghanmanshadi Z, Strætkvern KO, Xiong S, Martín C.   +6 more
europepmc   +1 more source