Results 121 to 130 of about 262,475 (236)

A Generative Neuro‐Symbolic AI for Protein Sequence Design

open access: yesAdvanced Science, EarlyView.
We introduce EffieDes, a neuro‐symbolic framework coupling deep learning‐based fitness landscape parameterization with exact automated reasoning. Unlike greedy sampling, EffieDes identifies sequences that globally optimize fitness while satisfying intricate design constraints.
Marianne Defresne   +12 more
wiley   +1 more source

Dynamic modelling, simulation and optimization of an extractive continuous alcoholic fermentation process

open access: yes, 2015
The conventional alcoholic fermentation is a typical inhibitory process, leading to low productivity and yield. The ethanol produced inhibits yeast cells, causing a reduction in the alcohol production rate and cell growth rate.
da Silva, FLH, Rodrigues, MI, Maugeri, F
core   +1 more source

Functionalized Biomimetic Scaffolds for Human‐Derived Auditory Neural Circuit Construction

open access: yesAdvanced Science, EarlyView.
In Vitro Auditory Circuit Model. ABSTRACT Damage to auditory circuits results in sensorineural hearing loss. However, the scarcity of human inner ear tissue significantly hinders the development of therapies to preserve auditory function, creating a critical need for reliable in vitro models.
Pan Feng   +12 more
wiley   +1 more source

Extractive Fermentation of Ethanol from Sweet Sorghum Using Vacuum Fractionation Technique: Optimization and Techno-Economic Assessment

open access: yes, 2018
Direct extraction of high purity ethanol from fermentation broth was investigated using a vacuum fractionation technique. Batch and repeated-batch extractive fermentation of ethanol were carried out using concentrated sweet sorghum as a carbon source ...
Jürgen Rarey   +5 more
core   +1 more source

A Global Methane Observation System to Reduce Uncertainty for Anthropogenic and Natural Sources and Sinks for Detecting and Attributing Climate Feedbacks

open access: yesAdvanced Science, EarlyView.
Conceptual illustration of a Global Ecosystem Methane Observing System (GEM‐OS) integrating satellites, aircraft, atmospheric networks, and ecosystem measurements to quantify methane emissions from anthropogenic and natural sources. The multi‐scale observing framework improves source attribution, reduces uncertainty in regional methane budgets, and ...
P. Ciais   +32 more
wiley   +1 more source

Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics

open access: yesAdvanced Science, EarlyView.
This review examines gastrointestinal capsule robots through a systems engineering lens, covering shell materials, actuation and localization strategies, diagnostic modalities, therapeutic interventions, and commercialization status. By mapping the complete technological chain from fabrication to clinical deployment, this work identifies critical gaps ...
Zengsheng Li   +8 more
wiley   +1 more source

Biosynthesis of 2-phenylethanol by yeasts  Kluyveromyces spp. in two-phase extractive fermentation

open access: yes, 2020
Darba mērķis bija izpētīt iespēju veikt laboratorijas mēroga biotehnoloģisku 2-feniletanola (2-PE) producēšanu ar raugiem Kluyveromyces spp. divfāzu ekstraktīvā fermentācijā, izmantojot laktozi saturošas barotnes, tai skaitā pārtikas industrijas ...
Aksjonova, Lidija
core  

Unveiling the Taxonomic Diversity and Unprecedented Biosynthetic Treasure of the Phylum Myxococcota

open access: yesAdvanced Science, EarlyView.
Natural products remain vital sources of therapeutics, and the phylum Myxococcota constitutes an especially rich reservoir for them. Based on decades of microbiological efforts, we present 154 new Myxococcota genomes and revise taxonomy quadrupling the number of families and genera.
Amay Ajaykumar Agrawal   +25 more
wiley   +1 more source

A REVIEW ON TWO PHASE BATCH EXTRACTION OF ALKALINE PROTEASES

open access: yesFUUAST Journal of Biology, 2013
Alkaline proteases are hydrolases that converts proteins into peptides performing better under low pH conditions. Numerous applications of alkaline proteases make them an important enzyme for industries.
NAPA SIWARUNGSON   +2 more
doaj  

Home - About - Disclaimer - Privacy