Results 111 to 120 of about 262,475 (236)

An Anti‐Amyloidogenic Approach to Specifically Block Memory Consolidation in Mice for Therapeutic Intervention

Advanced Science, EarlyView.
Functional amyloid conversion of the translation regulator CPEB3 is essential for long‐term memory persistence. This study demonstrates that targeting this molecular switch with the anti‐amyloidogenic peptide QBP1 selectively blocks CPEB3 fibrillation without disrupting phase separation.
Paula López‐García, Kerry R. McGreevy, Maria Eugenia Vaquero, Juan M. Suarez‐Rivero, Antonio Moreno‐Rodríguez, Antonio J. Pérez‐Pulido, Daniel Ramírez de Mingo, Anna Pallé, Helena Akiko Popiel, Andrea Santi, Mario D. Cordero, José Luis Trejo, Yoshitaka Nagai, Mariano Carrión‐Vázquez   +13 more
wiley   +1 more source

Extractive fermentation of L-lactic acid with immobilized Rhizopus oryzae in a three-phase fluidized bed

, 2007
A three-phase fluidized bed bioreactor was designed to perform the extractive fermentation of L-(+)-lactic acid by Rhizopus oryzae immobilized in calcium alginate beads.
Lin, Jianping, Zhou, Maohong, 卢英华, Lu, Yinghua, Zhao, Xiaowei, Luo, Shiyi   +5 more
core   +1 more source

A Perspective on the Applications of Triphasic Gas Storage in Electrochemical Systems

Advanced Science, EarlyView.
Gas storage in microporous materials positioned locally at an electrode or electrocatalyst surface enhances electrochemical processes. Abstract Microporous materials store gases under dry conditions (e.g., hydrogen or oxygen via physisorption), but in some cases microporous materials also show triphasic (e.g., in a solid|gas|liquid system) gas storage ...
Zhongkai Li, Corin T. Scott, Taku Suzuki‐Osborne, John P. Lowe, Dominic Taylor, Mariolino Carta, Neil B. McKeown, Andrew D. Burrows, Lucia H. Mascaro, Frank Marken   +9 more
wiley   +1 more source

Extractive Fermentation to produce biobased molecules

Poster. This research is part of the TRANSFeRMentation research group in INRAE's TRANSFORM departmentFermentation processes are a cornerstone of the bioeconomy.
Moussa, Marwen
core   +1 more source

Elevated butanol and acetone bio-production with integrated co-extraction in lime-buffered fermentation using high cell concentration

Case Studies in Chemical and Environmental Engineering
Butanol and acetone bioproduction face inhibition from excessive substrates, leading to acid crashes. Buffering stabilizes acidity and aids product formation, whereas simultaneous extraction prolongs cell productivity. This study aimed to enhance butanol
Maktum Muharja, Rizki Fitria Darmayanti, Yukihiro Tashiro, Kenji Sonomoto, Mamata Singhvi, Ghoson M. Daba, Ika Putri Nikmatur Rohmah, Abdul Halim, Dendy Satrio, Arief Widjaja   +9 more
doaj   +1 more source

Extractive Reserves: Building Natural Assets in the Brazilian Amazon [PDF]

In the Amazon rainforest, Brazil's rubber tappers were the first social group to challenge the predatory development model that is threatening ecological disaster there.
Anthony Hall
core  

Extractive fermentation of clavulanic acid by Streptomyces DAUFPE 3060 using aqueous two-phase system

, 2011
The influence of four variables, specifically polyethylene glycol (PEG) molar mass (400, 1,000, and 8,000 g/mol), concentrations of PEG and phosphate salts (15, 20, and 25% for both), and agitation intensity (110, 150, and 200 rpm), on clavulanic acid ...
Porto ALF, Pessoa Jr A, PEREGO, PATRIZIA, Lima Filho JL, Viana Marques DA, CONVERTI, ATTILIO   +5 more
core   +1 more source

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

Advanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes, Gabriela Silva, Mafalda Aleixo, Marta Gomes, Daniel Simão, Stephan J. Holtkamp, Diana D. Lobo, Pradeep Harish, Rosalind Jenkins, Lekh N. Dahal, Rui J. Nobre, Luís de Pereira de Almeida, Mark Trautwein, Paula M. Alves, Catarina Brito   +14 more
wiley   +1 more source

Non-linear predictive control of an extractive alcoholic fermentation process

, 2015
In this work a SISO non-linear predictive controller was developed for an extractive alcoholic fermentation process. The internal model of the controller was represented by a functional link network (FLN).
Maciel, R, Meleiro, LAC, Costa, AC
core   +1 more source

Targeted Restoration of the Microbial Tryptophan Oxidative Pathway Ameliorates Autism‐Like Behavioral and Synaptic Deficits

Advanced Science, EarlyView.
ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo, Caian He, Xiao Xiao, Jingmeng Li, Zilong Zhang, Ying He, Chuanchuan Wang, Jiale Zhao, Jun Gong, Jiarui Liang, Tian Yuan, Haiting Sun, Xuebo Liu, Chao Gao, Zhigang Liu   +14 more
wiley   +1 more source