Results 131 to 140 of about 2,050 (293)
Clavulanic acid purification by extractive fermentation using aqueous two-phase system
, 2009 A factorial design was employed to stady the influence of PEG molar mass, PEG concentration, phosphate salt concentration and agitation intensity on the extractive clavulanic acid fermentation by Streptomyces DAUFPE ...
A. Pessoa J.r. +3 more
core
Sex‐Specific Regulation of Glycemic Homeostasis by Theabrownin from Pu‐erh Tea
Advanced Science, EarlyView.Pu‐erh tea's key component, theabrownin (TB), lowers blood glucose in a sex‐specific manner. In females, estrogen boosts intestinal MUC2 production, which dramatically enhances TB's ability to inhibit the carbohydrate‐digesting enzyme α‐glucosidase.
Yang Li +22 more
wiley +1 more source
A REVIEW ON TWO PHASE BATCH EXTRACTION OF ALKALINE PROTEASES
FUUAST Journal of Biology, 2013 Alkaline proteases are hydrolases that converts proteins into peptides performing better under low pH conditions. Numerous applications of alkaline proteases make them an important enzyme for industries.
NAPA SIWARUNGSON +2 more
doaj
Antidiabetic effect of dried sweet potato extract with fermented lettuce extracts
Food Science and BiotechnologyFermented plant extracts are known to exhibit antidiabetic effects. However, antidiabetic activity of fermented lettuce extracts (FHE) and dried sweet potatoes with FHE remains unexplored. This study analyzed γ-aminobutyric acid (GABA), antioxidant, and polyphenol levels in such extracts, and an in vivo oral glucose tolerance, an oral sucrose tolerance,
Kim, Eunjin +8 more
openaire +3 more sources
Advanced Science, EarlyView.Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang +11 more
wiley +1 more source
Advanced Science, EarlyView.A time‐multiplexed nanobody‐functionalized organic electrochemical transistor enables rapid and sensitive detection of three respiratory viral proteins from saliva. Sequentially addressed multi‐gate electrodes on a shared channel achieve around 1 fm detection within 15 min without sample preprocessing. Clinical validation demonstrates high specificity,
Tianrui Chang +13 more
wiley +1 more source
Advanced Science, EarlyView.A comprehensive meta‐analysis of expression quantitative trait loci (eQTLs) across five diverse tomato populations reveals a high‐resolution atlas of transcriptional regulation and uncovers conserved and population‐specific regulatory architectures underlying fruit nutritional quality traits, including flavonoids, sugars, organic acids, carotenoids ...
Jiantao Zhao +14 more
wiley +1 more source
Advanced Science, EarlyView.Monoclonal antibodies are powerful anticancer therapeutics targeting tumor‐associated antigens. Mass spectrometry enables precise and accurate quantification of mAbs in tumor plasma and healthy organs. Unlike ligand binding assay and radioactivity, mass spectrometry does not suffer from matrix effects and labelling artefacts while facilitating method ...
Domenico Ravazza +9 more
wiley +1 more source
Advanced Science, EarlyView.Inflammatory bowel disease (IBD) pathogenesis remains unclear. This study reveals that thymus‐originated IL‐7R‐enriched extracellular vesicles exacerbate colitis by promoting neutrophil extracellular traps via a thymus‐gut axis, uncovering an inter‐organ communication mechanism in inflammatory bowel disease pathogenesis.
Yao Liao +21 more
wiley +1 more source