Developmental plasticity, cell fate specification and morphogenesis in the early mouse embryo [PDF]
A critical point in mammalian development is when the early embryo implants into its mother's uterus. This event has historically been difficult to study due to the fact that it occurs within the maternal tissue and therefore is hidden from view. In this
Bedzhov, Ivan +3 more
core +2 more sources
Heterogeneous X inactivation in trophoblastic cells of human full-term female placentas [PDF]
In female mammalian cells, one of the two X chromosomes is inactivated to compensate for gene-dose effects, which would be otherwise doubled compared with that in male cells.
Gillis, A.J.M. (Ad) +4 more
core
The genome-defence gene Tex19.1 suppresses LINE-1 retrotransposons in the placenta and prevents intra-uterine growth retardation in mice [PDF]
DNA methylation plays an important role in suppressing retrotransposon activity in mammalian genomes, yet there are stages of mammalian development where global hypomethylation puts the genome at risk of retrotransposition-mediated genetic instability ...
Aravin +80 more
core +1 more source
Expression of parathyroid hormone-related protein mRNA by uterine tissues and extraembryonic membranes during gestation in rats [PDF]
Felix Beck, J. Tucci, P. V. Senior
openalex +1 more source
Citation: 'extraembryonic membrane' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.10700 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire +1 more source
Bmi1 facilitates primitive endoderm formation by stabilizing Gata6 during early mouse development [PDF]
International audienceThe transcription factors Nanog and Gata6 are critical to specify the epiblast versus primitive endoderm (PrE) lineages. However, little is known about the mechanisms that regulate the protein stability and activity of these factors
Azuara, Veronique +12 more
core +4 more sources
Pre-implantation maternal uterine effects on embryo growth and development : an investigation using models of maternal constraint in sheep : a thesis presented in fulfilment of the requirements for the degree of Doctor of Philosophy in Animal Science, Massey University, Turitea, Palmerston North, New Zealand [PDF]
Listed in 2017 Dean's List of Exceptional ThesesPrenatal development and growth are critical to survival of the fetus and neonate. Recent evidence suggests that a critical period for determining growth is the pre-implantation period of pregnancy during
Fermin, Lisanne Monique
core
Distinct mechanisms regulate Cdx2 expression in the blastocyst and in trophoblast stem cells [PDF]
The first intercellular differences during mammalian embryogenesis arise in the blastocyst, producing the inner cell mass and the trophectoderm. The trophectoderm is the first extraembryonic tissue and does not contribute to the embryo proper, its ...
Azuara, V +9 more
core +3 more sources
Current status of in vitro differentiation of stem cells into gametes [PDF]
From an evolutionary point of view, the gametes are the cells in the body that matter the most as they are the ones who transmit their genes to the next generation ensuring continuation of the species. Being able to generate mature oocytes in vitro is of
Chuva de Sousa Lopes, Susana Marina +1 more
core +1 more source
Differential gene and protein expression in pig nuclear transfer extraembryonic membranes and blastocyst stage embryos [PDF]
Kristin M. Whitworth
openalex +1 more source

