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Paget's disease most commonly affects the breast. Extramammary involvement is rare, and the most commonly affected sites are the vulva, anus, perianal region, and axilla. The disease may progress to invasive adenocarcinoma or synchronous cancers.
Ornella Sari Cassol +5 more
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Extramammary Paget's disease of the penis: a case report and review of the literature
Introduction Extramammary Paget's disease is a rare cutaneous, slow growing, intraepithelial adenocarcinoma developing in the apocrine gland-bearing areas. Isolated Paget's disease of the penis is extremely rare. Case presentation We describe the case of
Ekwueme Kingsley C +2 more
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Mammary Paget's disease occurring after mastectomy [PDF]
Background Mammary Paget's disease and extramammary Paget's disease are neoplastic conditions, in which there is intraepithelial (usually intraepidermal) infiltration by neoplastic cells showing glandular differentiation.
Piubello Quirino +3 more
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Primary invasive triple extramammary Paget's disease with regional lymph node metastasis: A case report and review of the literature [PDF]
Extramammary Paget's disease (EMPD) is a rare intraepidermal carcinoma and predominantly involves apocrine gland-bearing areas, such as anogenital regions and axillae.
Chi-Hung Wu, Chen-Yi Wu
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Practice Patterns in Extramammary Paget's Disease
Background In patients with Extramammary Paget's Disease (EMPD), a rare intraepithelial adenocarcinoma, wide local excision (WLE) has historically been the standard of treatment despite high rates of positive margins and recurrence.
Yasmine Mohseni +4 more
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Extramammary Paget's Disease Associated With Genital Wart and Lichen Sclerosus
Extramammary Paget’s disease is an uncommon intraepithelial adenocarcinoma in genital and perianal regions. Genital wart is the most common sexually transmitted disease caused by human papilloma viruses and vulval lichen sclerosus is chronic pruritic ...
Rana Rafiei +4 more
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Pagetoid spread of urothelial carcinoma controlled without resection
Introduction Extramammary Paget's disease is an eczematous skin condition that affects the vulva and perineum. Extramammary Paget's disease secondary to urothelial carcinoma is a rare condition that is typically treated with invasive surgical resection ...
Shutaro Yamamoto +9 more
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Extramammary Paget disease [PDF]
In 1874, Sir James Paget first described Paget disease of the nipple, also known as mammary Paget disease. In 1889, extramammary Paget disease (EMPD) of the scrotum and penis was identified. Although mammary and extramammary Paget disease are both characterized by epidermal Paget cells and share a similar clinical presentation, their uniqueness lies in
St. Claire, Kayla +3 more
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Extramammary Paget’s Disease of the Vulva: Report of Two Cases
Extramammary Paget’s disease is a rare condition, affecting 6.5% of all patients with Paget’s disease. The most common extramammary site is the vulvar area. Although diagnosis in some patients is difficult to set, early diagnosis is of high importance in
Christoforos S. Kosmidis +9 more
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A Case Report of Familial Extramammary Paget's Disease in Female Siblings
Extramammary Paget’s disease (EMPD) is a rare intraepithelial neoplasm that occurs in apocrine-bearing areas of skin. Most EMPD patients initially present with chronic pruritic eczematous lesions involving genitalia, perineum and perianal area.
Thanachat Rutnumnoi, Charussri Leeyaphan
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