Results 41 to 50 of about 5,282,350 (229)

Protocol for stage 2 of the GaP study (genetic testing acceptability for Paget's disease of the bone) : a questionnaire study to investigate whether relatives of people with Paget's disease would accept genetic testing and preventative treatment if they were available [PDF]

, 2008
Background: Paget's disease of bone (PDB) disrupts normal bone architecture and causes pain, deformity, deafness, osteoarthritis, and fractures. Genetic factors play a role in PDB and genetic tests are now conducted for research purposes.
Ralston, Stuart H., Charnock Keith, Campbell, MK, Graeme MacLennan, John Weinman, McCallum Marilyn, Robertson, C., Weinman, John, Miedzybrodska Zosia, Langston Anne L, Weinman John, Vikki A Entwistle, Campbell, Marion K, McCallum, M., Robertson Clare, Entwistle, V.A, Campbell, Marion K., Francis, J., Charnock, K., Ralston, Stuart H, Langston, A. L., Robertson, Clare, MacLennan, Graeme Stewart, Entwistle Vikki A, Campbell, M K, Langston, AL, Francis, Jillian Joy, Marteau Theresa, Zosia Miedzybrodska, Miedzybrodska, Z, Langston, Anne L, Entwistle, Vikki A., Marilyn McCallum, Langston, A L, Entwistle, Vikki, Ralston, SH, Campbell, Marion Kay, Anne L Langston, Jill Francis, Ralston, S H, Miedzybrodzka, Zosia, Marie Johnston, Charnock, Keith, Francis, Jill, Weinman, J, Ralston, S.H, Weinman, J., Langston, A.L, Robertson, C, Entwistle, V A, Clare Robertson, McCallum, Marilyn, Ralston, S., Johnston Marie, Marteau, T, Campbell Marion K, Miedzybrodzka, Z., Entwistle, Vikki A, Campbell, M.K, Theresa Marteau, Johnston, M, Stuart H Ralston, Langston, Anne L., Entwistle, V., Johnston, M., Francis Jill, Ralston Stuart H, MacLennan, G, Campbell, M. K., Marteau, T., Entwistle, VA, Johnston, Marie, Marion K Campbell, Maclennan, Graeme, Miedzybrodska, Zosia, McCallum, M, MacLennan Graeme, Keith Charnock, Francis, J, Charnock, K, Marteau, Theresa, MacLennan, G.   +81 more
core   +2 more sources

Extramammary Paget's disease

BJOG: An International Journal of Obstetrics & Gynaecology, 2005
EMPD is a rare condition that poses difficulties of diagnosis and management. Suspicious skin lesions not responding to topical therapy after four to six weeks should be biopsied to exclude EMPD. There is an associated malignancy in 20% to 30% of cases and a detailed investigation of the patient should be carried out at presentation to exclude invasive
Crosbie, Emma; id_orcid 0000-0003-0284-8630, Shepherd, Victoria, Davidson, Emma J., Davies-Humphreys, John   +3 more
openaire   +4 more sources

Metastatic Extramammary Paget’s Disease: Pathogenesis and Novel Therapeutic Approach

Frontiers in Oncology, 2018
Extramammary Paget’s disease (EMPD) is a rare, slow-growing, cutaneous adenocarcinoma that usually originates in the anogenital area and axillae outside the mammary glands.
K. Fukuda, T. Funakoshi
semanticscholar   +1 more source

Extramammary Paget’s disease

BJR|case reports, 2016
The purpose of this report is to describe an unusual case of extramammary Paget's disease with urethral and lymph node infiltration and demonstrate the role of MRI in the pre-operative period for the assessment, management and prognosis of the disease.
Vasquez, Andres, Dominguez, Cristina, Rolon, Mariam   +2 more
openaire   +2 more sources

Boron neutron capture therapy for vulvar melanoma and genital extramammary Paget’s disease with curative responses

Cancer Communications, 2018
BackgroundAlthough the most commonly recommended treatment for melanoma and extramammary Paget’s disease (EMPD) of the genital region is wide surgical excision of the lesion, the procedure is highly invasive and can lead to functional and sexual problems.
J. Hiratsuka, N. Kamitani, R. Tanaka, Eisaku Yoden, Ryuji Tokiya, Minoru Suzuki, R. Barth, K. Ono   +7 more
semanticscholar   +1 more source

A Case of Secondary Extramammary Paget's Disease Aroundthe Cutaneous Stoma after Radical Cystectomy [PDF]

, 2017
We present a case of secondary extramammary Paget's disease around the cutaneous ureterostomy stoma after radical cystectomy. An 85-year-old man with bacillus calmette-guérin refractory high-grade urothelial carcinoma underwent radical cystectomy and ...
光森, 健二, 西村, 一男, 大久保, 和俊, 神田, 壮平, 高橋, 毅, 飛田, 卓哉, 嶋田, 俊秀, 河野, 仁   +7 more
core   +1 more source

Axillary masses as clinical manifestations of male sweat gland carcinoma associated with extramammary Paget’s disease and accessory breast carcinoma: two cases report and literature review

World Journal of Surgical Oncology, 2022
Background Male cases of accessory breast carcinoma and sweat gland carcinoma associated with extramammary Paget’s disease of the axilla are uncommon.
Jing Wu, Hongdan Chen, Juanhui Dong, Yong Cao, Wei Li, Fan Zhang, Xiaohua Zeng   +6 more
doaj   +1 more source

Implications of Adnexal Invasions in Primary Extramammary Paget’s Disease: A Systematic Review

International Journal of Innovative Science and Research Technology
Extramammary Paget’s disease (EMPD) is an erratic malignant skin disorder primarily affecting skin areas abundant with skin appendages like hair follicles. The vulva is most involved site, followed by genital areas, penoscrotal regions and axillary skin.
Sabita Aryal, Ye-Qiang Liu
semanticscholar   +1 more source

Extramammary Paget's disease of the Vulva [PDF]

BMJ Case Reports, 2013
Vulvar Paget's disease is an extremely rare neoplasm that accounts for less than 1% of the vulvar malignancies. We present a case of a 75-year-old woman, who had an eczematoid lesion involving the labia majora and minora bilaterally, with infiltration to the clitoris. Enlarged non-fixed lymph nodes were palpable in the inguinal region bilaterally.
Paschalis, Gavriilidis, Konstantinos, Chrysanthopoulos, Domniki, Gerasimidou   +2 more
openaire   +2 more sources

CDX2 expression in cutaneous metastatic carcinomas and extramammary Paget's Disease.

, 2009
International audienceBACKGROUND: CDX2 is a gene involved in the regulation of intestinal cell proliferation/differentiation. It is considered specific for enterocytes and has been used for the diagnosis of primary and metastatic colon adenocarcinoma ...
Lora, Viviana, Kanitakis, Jean
core   +2 more sources