Results 41 to 50 of about 4,842,936 (172)

One‐year follow‐up after fractionated ultra‐high‐dose‐rate FLASH radiotherapy in patient with extramammary Paget disease of the scrotum

Precision Radiation Oncology, Volume 10, Issue 2, Page 120-126, June 2026.
An elderly male patient with extramammary Paget disease of the scrotum and multiple metastases was treated with fractionated FLASH‐RT (40 Gy in 5 fractions) in the scrotal lesion. Abstract Objective Ultrahigh‐dose‐rate radiotherapy (FLASH‐RT) has been shown to reduce radiation‐induced normal tissue injury in preclinical studies.
Hui Luo, Chengliang Yang, Ronghu Mao, Leijie Ma, Hongchang Lei, Peng Chen, Yanping Zhang, Meng Xu, Chao Wang, Yiwu Wang, Mingxia Wu, Chanjun Sun, Han Liu, Hui Liu, Hong Ge   +14 more
wiley   +1 more source

Anal gland adenocarcinoma in situ with pagetoid spread: a case report

Surgical Case Reports, 2018
Background Anal gland carcinoma with perianal Paget’s disease is rare, and anal gland carcinoma in situ is extremely rare. No cases of anal gland carcinoma in situ with pagetoid spread have been previously reported. Case presentation Physical examination
Kohei Ishioka, Fumikazu Koyama, Hiroyuki Kuge, Takashi Inoue, Shinsaku Obara, Takayuki Nakamoto, Yoshiyuki Sasaki, Yasuyuki Nakamura, Maiko Takeda, Chiho Ohbayashi, Masamitsu Kuwahara, Masayuki Sho   +11 more
doaj   +1 more source

Boron Neutron Capture Therapy at a Crossroads: Translational Gap and Emerging Delivery Agents

Chemistry – A European Journal, Volume 32, Issue 17, 5 May 2026.
This review surveys recent advances in boron delivery agents for BNCT, emphasizing the shift from classical small molecules to multifunctional nanocarriers and theranostic systems. By integrating targeting, imaging, and therapy, next‐generation boron compounds aim to bridge the gap between (bio)chemical innovation and clinical translation.
Christoph Selg, Evamarie Hey‐Hawkins
wiley   +1 more source

Extramammary Paget Disease of Peristomal Skin Secondary to Bladder Urothelial Carcinoma [PDF]

, 2022
Extramammary Paget disease (EMPD) is a rare, cutaneous condition, which can present secondary to underlying carcinoma as an eczematoid rash that often mimics other conditions.
Scott Gregory, Victoria Dukharan, Adriana L Della Porta, Gulsun Erdag   +3 more
core   +1 more source

Invasive Vulval Paget’s disease treated with primary radiotherapy: A rare case report and literature review

Gynecologic Oncology Reports, 2020
Extramammary Vulval Paget’s Disease (VPD) is rare neoplasm of post-menopausal women. In relatively young perimenopausal patients, it can cause both diagnostic dilemma and therapeutic challenges. Majority of VPD is of non-invasive variety.
Avir Sarkar, S.C. Saha, Pooja Sikka, Neha Kumari, Pranab Dey, Bhavana Rai   +5 more
doaj   +1 more source

Nonmass‐Forming Type Anocanal Cancer With Pagetoid Spread With a Challenging Differential Diagnosis: A Case Report

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Pagetoid spread (PS) of anorectal cancer is relatively rare and is associated with poor prognosis compared with Extramammary Paget disease. It is therefore essential to accurately differentiate between the two entities. In PS cases, the primary tumor lesion is usually obvious; however, this is not the case in nonmass‐forming type anorectal ...
Mizunori Yaegashi, Ryo Sugimoto, Hiroaki Shimada, Akira Sasaki   +3 more
wiley   +1 more source

Potential Use of Bisphosphonates in Invasive Extramammary Paget’s Disease: An Immunohistochemical Investigation [PDF]

, 2013
Invasive extramammary Paget’s disease (EMPD) is relatively rare and is reported to be highly metastatic to lymph nodes or even other organs, including bone.
Setsuya Aiba, Taku Fujimura, Taku Fujimura, Yumi Kambayashi, Sadanori Furudate   +4 more
core   +1 more source

Trop2 Expression in Extramammary Paget’s Disease and Normal Skin

, 2021
Extramammary Paget’s disease (EMPD) is a rare skin cancer arising in the apocrine gland-rich areas. Most EMPD tumors are dormant, but metastatic lesions are associated with poor outcomes owing to the lack of effective systemic therapies. Trophoblast cell
Hiroki Hashimoto, Yumiko Kaku-Ito, Takamichi Ito, Maho Murata, Yoshinao Oda, Keiko Tanegashima, Yuka Tanaka   +6 more
core   +1 more source

Invasive Acantholytic Extramammary Paget's Disease of the Vulva With Mammary Carcinoma-Like Differentiation and MMR Loss: Report of an Unusual Case and Its Clinical Mimics

Gynecologic Oncology Reports
Background: Paget’s disease (EMPD) of the vulva primarily affects postmenopausal women and can present significant challenges in early clinical detection.Case Presentation: We report an exceedingly rare case of invasive acantholytic extramammary Paget’s ...
Jessica Claus, Janina Pearce, Areta Bojko, Padmini Manrai, M.Ruhul Quddus, Shivali Marketkar   +5 more
doaj   +1 more source

Prostate carcinoma metastatic to the skin as an extrammamary Paget’s disease

Diagnostic Pathology, 2012
Aim The current paper describes a case of prostatic adenocarcinoma metastatic to the skin presenting as an extrammamary Paget's disease, a very rare and poorly characterised morphological entity. We report a case of prostatic carcinoma metastatic to skin
Petcu Eugen, Gonzalez-Serva Aldo, Wright Robert G, Slevin Mark, Brinzaniuc Klara   +4 more
doaj   +1 more source