A Multifaceted Holistic Review of the Literature on Scar Dermatoses
ABSTRACT Many cutaneous diseases originate or manifest in scars. Scars are areas of compromised skin, which renders them a vulnerable cutaneous district for diseases to develop. The pathophysiology explaining why some dermatoses grow in scars is not yet thoroughly explored. The present study reviews the present literature on scar dermatoses.
Dana Maria Khoury +5 more
wiley +1 more source
Dramatic Clinical Response of Relapsed Metastatic Extramammary Paget’s Disease to Trastuzumab Monotherapy [PDF]
We report the first case of 68-year-old Japanese woman with metastatic HER2-positive extramammary Paget’s disease that showed the validity of trastuzumab monotherapy.
Y. Togawa +5 more
core +1 more source
Scrotal squamous cell carcinoma: Two HPV‐negative cases with probable UV‐ induced pathogenesis
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Daniel Craus +7 more
wiley +1 more source
Consensus on Human Epidermal Growth Factor Receptor 2 Overexpression Testing in Pan‐Tumor
This is the first pan‐tumor human epidermal growth factor receptor 2 (HER2) testing consensus established by a national expert panel in China, addressing critical gaps in HER2 overexpression testing across solid tumors beyond breast and gastric cancers.
Zhe Wang +17 more
wiley +1 more source
Perianal Paget’s disease as spread from non‐invasive colorectal adenomas
AIMS: Paget’s disease of the perianal skin is a rare form of extramammary Paget’s disease, and may be a primary intraepithelial adnexal neoplasm or secondary due to spread from an underlying colorectal lesion, nearly always colorectal adenocarcinoma ...
Danielle Hutchings +11 more
core +1 more source
Accumulation of exhausted CD8+ T cells in extramammary Paget’s disease [PDF]
Cancer immunotherapy has highlighted the clinical relevance of enhancing anti-tumor response of CD8+ T cells in several cancer types. Little is known, however, about the involvement of the immune system in extramammary Paget’s disease (EMPD). We examined
Takeru Funakoshi (756285) +56 more
core +1 more source
Vulvar Adenocarcinoma With Pagetoid Spread: A Case Report
Background In rare cases, cancer cells adjacent to the skin migrate intraepithelially and reach the epidermis, presenting a histological appearance similar to that of Paget's disease; this phenomenon is termed pagetoid spread. Herein, we report a case of
Kazuaki Nishimura +5 more
doaj +1 more source
Perianal Paget's Disease: A Case Report
ABSTRACT Perianal Paget's disease is rare and may be secondary to an underlying anorectal adenocarcinoma. Full‐thickness biopsy with immunohistochemistry is key to distinguish primary from secondary disease and to guide staging. Wide local excision is standard, while radiotherapy is a reasonable option when radical surgery is declined.
Daniela Lira +5 more
wiley +1 more source
Perianal Paget’s Disease in a Forty-Five-Year-Old Man and Review of the Literature [PDF]
Introduction Extramammary Paget’s disease is a rare neoplasm of the skin that might develop in perianal region. Although different management options are available, wide local excision is still the method of choice.
Yavar Shams Hojjati +3 more
doaj +1 more source
Dermatologic Features of Endocrine Tumor Syndromes—Systematic Review and Meta‐Analysis
ABSTRACT Endocrine tumor syndromes, including multiple endocrine neoplasia types 1, 2A, and 2B (MEN1, MEN2A, MEN2B), Carney complex (CNC), and PTEN hamartoma tumor syndrome (PHTS), are hereditary conditions characterized by multisystem tumor development.
Sára Pálla +8 more
wiley +1 more source

