Results 51 to 60 of about 5,220,417 (172)
Clinical Case Reports, Volume 14, Issue 5, May 2026.ABSTRACT Pagetoid spread (PS) of anorectal cancer is relatively rare and is associated with poor prognosis compared with Extramammary Paget disease. It is therefore essential to accurately differentiate between the two entities. In PS cases, the primary tumor lesion is usually obvious; however, this is not the case in nonmass‐forming type anorectal ...
Mizunori Yaegashi +3 more
wiley +1 more source
Scrotal squamous cell carcinoma: Two HPV‐negative cases with probable UV‐ induced pathogenesis
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Daniel Craus +7 more
wiley +1 more source
A Multifaceted Holistic Review of the Literature on Scar Dermatoses
International Wound Journal, Volume 23, Issue 5, May 2026.ABSTRACT Many cutaneous diseases originate or manifest in scars. Scars are areas of compromised skin, which renders them a vulnerable cutaneous district for diseases to develop. The pathophysiology explaining why some dermatoses grow in scars is not yet thoroughly explored. The present study reviews the present literature on scar dermatoses.
Dana Maria Khoury +5 more
wiley +1 more source
Trop2 Expression in Extramammary Paget’s Disease and Normal Skin
, 2021 Extramammary Paget’s disease (EMPD) is a rare skin cancer arising in the apocrine gland-rich areas. Most EMPD tumors are dormant, but metastatic lesions are associated with poor outcomes owing to the lack of effective systemic therapies. Trophoblast cell
Hiroki Hashimoto +6 more
core +1 more source
Vulvar Adenocarcinoma With Pagetoid Spread: A Case Report
Cancer ReportsBackground In rare cases, cancer cells adjacent to the skin migrate intraepithelially and reach the epidermis, presenting a histological appearance similar to that of Paget's disease; this phenomenon is termed pagetoid spread. Herein, we report a case of
Kazuaki Nishimura +5 more
doaj +1 more source
Consensus on Human Epidermal Growth Factor Receptor 2 Overexpression Testing in Pan‐Tumor
Cancer Innovation, Volume 5, Issue 2, April 2026.This is the first pan‐tumor human epidermal growth factor receptor 2 (HER2) testing consensus established by a national expert panel in China, addressing critical gaps in HER2 overexpression testing across solid tumors beyond breast and gastric cancers.
Zhe Wang +17 more
wiley +1 more source
Perianal Paget's Disease: A Case Report
Clinical Case Reports, Volume 14, Issue 4, April 2026.ABSTRACT Perianal Paget's disease is rare and may be secondary to an underlying anorectal adenocarcinoma. Full‐thickness biopsy with immunohistochemistry is key to distinguish primary from secondary disease and to guide staging. Wide local excision is standard, while radiotherapy is a reasonable option when radical surgery is declined.
Daniela Lira +5 more
wiley +1 more source
Dermatologic Features of Endocrine Tumor Syndromes—Systematic Review and Meta‐Analysis
International Journal of Dermatology, Volume 65, Issue 3, Page 464-488, March 2026.ABSTRACT Endocrine tumor syndromes, including multiple endocrine neoplasia types 1, 2A, and 2B (MEN1, MEN2A, MEN2B), Carney complex (CNC), and PTEN hamartoma tumor syndrome (PHTS), are hereditary conditions characterized by multisystem tumor development.
Sára Pálla +8 more
wiley +1 more source
Advanced Science, Volume 13, Issue 2, 9 January 2026.Natural killer cells, central to anti‐tumor defense, undergo unexpected reprogramming within the tumor microenvironment. Instead of producing IFN‐γ and TNF‐α, they elevate amphiregulin, a tumor‐promoting factor. This shift is linked to glucocorticoid receptor activity and prostaglandin signaling.
Qin Wei +8 more
wiley +1 more source