Results 71 to 80 of about 4,842,936 (172)

The Roles of MicroRNAs, Oncogenes, and Tumor Suppressor Gene Molecular Subtypes of Breast Cancer: Therapeutic Potential of Pharmaceutical and Natural Products

International Journal of Breast Cancer, Volume 2026, Issue 1, 2026.
Background Breast cancer (BC) is the most common malignancy among women, with 2.3 million new cases and over 670,000 deaths annually. Despite advances in detection and therapy, relapse, metastasis, and resistance remain significant challenges. Tumor suppressor genes (TSGs) regulate abnormal cell division, whereas oncogenes, which arise from proto ...
Md. Sadikuj Jaman, Md. Maniruzzaman, Md. Rokibul Hasan Bhuiyan, Md Shajedul Haque, Irfan Ahmad   +4 more
wiley   +1 more source

Sixteen Years of a Pruritic Unilateral Axillary Eruption: A Rare Presentation of Extramammary Paget’s Disease

, 2017
Extramammary Paget’s Disease (EMPD) is a rare intraepithelial adenocarcinoma of apocrine gland-bearing skin. The most common sites affected are the vulva in women and the perinanal, scrotal, and penile regions in men.
Amy R Weiss, Mark Jacobson, Robbie B Drossner   +2 more
core   +1 more source

Extramammary Paget’s Disease and Melanoma: 2 Cases of Double Cancers

Case Reports in Dermatology, 2020
Extramammary Paget’s disease (EMPD) is a rare intraepidermal neoplastic disease. There is a well-known relationship between EMPD and underlying malignancy. However, only a few cases of EMPD and cutaneous melanoma have been reported previously.
Erika Lydrup, Jais Oliver Berg, Sofie Vetli Hjorth, Lisbet Rosenkrantz Hølmich, Jørgen Lock-Andersen, Annette Hougaard Chakera   +5 more
doaj   +1 more source

First Case of Primary Breast Melanoma in Central America: Case Report and Literature Review

Clinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT Primary breast melanoma is an exceedingly rare neoplasm, accounting for < 0.5% of all malignant breast tumors. Its scarcity and highly variable clinical presentation often delay diagnosis and complicate management. We report the case of a 55‐year‐old woman with a primary non‐cutaneous melanoma of the right breast initially misdiagnosed as high‐
Ana García‐Urbina, Denis Espinoza‐Vásquez, Johanna Obregón‐Silva, Arlin Montoya Rodríguez   +3 more
wiley   +1 more source

Perianal extramammary Paget’s disease: a rare case report and review of the literature [PDF]

Surgical & Cosmetic Dermatology
Extramammary Paget’s disease (EMPD) is a rare malignancy and is quite difficult to diagnose. We report a case of a 51-year-old female patient with perianal EMPD.
Gabriela Alfier, Srecko Budi, Zrinka Sudar-Magas, Milan Miocinovic, Saida Rezakovic   +4 more
doaj   +1 more source

Triple Extramammary Paget’s Disease: A Case Report

, 2020
Extramammary Paget’s disease (EMPD) is a rare malignant neoplasm of the apocrine sweat gland-bearing skin in the genital, perianal, or axillary region.
정기양, 오병호, 김제민
core  

Mammary and Extramammary Paget’s Disease Presented Different Expression Pattern of Steroid Hormone Receptors [PDF]

, 2017
Background and Objectives. Paget’s disease (PD) is a rare intraepithelial adenocarcinoma, which is composed of mammary (MPD) and extramammary Paget’s disease (EMPD). Currently, the published literature contains scant data on expression pattern of steroid
Songxia Zhou, Ruiqin Mai, Weixiang Zhong, Guohong Zhang   +3 more
core   +1 more source

An Asymptomatic Lesion on the Penis

JEADV Clinical Practice, Volume 5, Issue 1, Page 309-311, March 2026.
Brandon Tan, Karen Cheung, Xin Liu, Alexis Daniel Lara Rivero   +3 more
wiley   +1 more source

The Perianal Mirage: Case of Primary Perianal Paget’s Disease

Apollo Medicine
Background: Paget’s disease is rare and arises from the apocrine glands of skin. Perianal Paget’s disease is very rare form of extramammary Paget’s disease.
Harsh J. Shah, Swapnil V. Sharma, Vinayak N. Dave, Aniket Dave   +3 more
doaj   +1 more source

CDK4: A Novel Therapeutic Target for Extramammary Paget’s Disease

, 2021
<jats:sec><jats:title>Background</jats:title><jats:p>The outcome of extramammary Paget’s disease (EMPD) is poor when it progresses to metastasis because of the lack of effective systemic therapies.
Kaku-Ito, Yumiko, Hashimoto, Hiroki, Oda, Yoshinao, Ito, Takamichi   +3 more
core   +1 more source