Results 41 to 50 of about 2,223 (231)
Depigmentation of the vulvar area: Is it an alarming sign?
Clinical Case Reports, 2022 A 34‐year‐old female patient presented with recurrent bilateral hypopigmented macules on the labia majora. The lesions were treated with topical steroids, which led to mild improvement, but erosive plaques developed after discontinuing the treatment ...
Reem Diab +5 more
doaj +1 more source
A true epidermotropic apocrine neoplasm in the form of perianal Paget’s disease: a case report [PDF]
, 2013 INTRODUCTION: Extramammary Paget’s disease is an uncommon intraepithelial neoplasm that arises in areas rich in apocrine glands. Treatment includes wide surgical excision and nonsurgical modalities.
Blagica Dukova +3 more
core +1 more source
Journal of Coloproctology, 2019 Paget's disease most commonly affects the breast. Extramammary involvement is rare, and the most commonly affected sites are the vulva, anus, perianal region, and axilla. The disease may progress to invasive adenocarcinoma or synchronous cancers.
Ornella Sari Cassol +5 more
doaj +1 more source
Frequent expression of the breast differentiation antigen NY-BR-1 in mammary and extramammary Paget's disease [PDF]
, 2010 While mammary Paget's disease (MPD) is clearly linked to breast cancer, the histogenesis of extramammary Paget's disease (EMPD) is controversial. Recently NY-BR-1, a differentiation antigen expressed in the breast and in skin adnexal structures was ...
Abbott +37 more
core +1 more source
BJOG: An International Journal of Obstetrics & Gynaecology, 2005 EMPD is a rare condition that poses difficulties of diagnosis and management. Suspicious skin lesions not responding to topical therapy after four to six weeks should be biopsied to exclude EMPD. There is an associated malignancy in 20% to 30% of cases and a detailed investigation of the patient should be carried out at presentation to exclude invasive
Crosbie, Emma +3 more
openaire +4 more sources
Extramammary Paget’s disease affecting the external auditory canal: a case report [PDF]
, 2013 INTRODUCTION: Extramammary Paget’s disease is a rare histological type of intraepithelial adenocarcinoma that mainly affects apocrine sweat gland-rich areas. Predilection sites include the anogenital region and, less commonly, the axillae.
Ana Maria da Silva Castro +5 more
core +1 more source
Reflectance confocal microscopy of mammary Paget disease
Dermatology Practical & Conceptual, 2017 Mammary Paget disease is the intraepidermal adenocarcinoma of the nipple area which is characterized usually by a well-demarcated eczematous plaque. Reflectance confocal microscopy (RCM), is an in vivo noninvasive diagnostic tool with a high-resolution ...
Fezal Ozdemir +6 more
doaj +1 more source
Surgical treatment of Paget’s disease of the vulva using Mohs micrographic surgery, followed by vulvar reconstruction using the “lotus petal” suprafascial flap [PDF]
, 2016 Vulvar Paget’s disease is an extramammary manifestation of Paget’s disease, a cutaneous neoplasm that clin-ically appears as sharply defined erythematous plaques with irregular borders that usually affect apocrine gland-bearing skin. Extramammary Paget’s
Herraiz Roda, José Luis +5 more
core +3 more sources
Dermatology Online Journal, 2011 We report the case of a 60-year-old man with penile-scrotal extramammary Paget disease (EMPD). The patient initially underwent Mohs micrographic surgery, but the margins remained positive after several sections; multiple scouting punch biopsies used to define the extent of the tumor were also positive.
Hartman, Rachael +4 more
openaire +4 more sources
Androgen receptor and 5α-reductase immunohistochemical profiles in extramammary Paget disease [PDF]
, 2010 Background Extramammary Paget disease is an uncommon skin tumour occurring mostly in the genitoperineal region. Previous reports have shown frequent expression of androgen receptor, suggesting a tumour-proliferative effect of androgens on Paget cells ...
Inoue Masaki +5 more
core +3 more sources