Results 81 to 90 of about 2,889 (184)

Antithrombocytopenic and immunomodulatory potential of metabolically characterized aqueous extract of Carica papaya leaves

open access: yesPharmaceutical Biology, 2017
Context: Carica papaya Linn. (Caricaceae) leaf (CPL) juice has long been traditionally used in ethnomedicine for dengue fever. Objective: The study examines the effects of standardized CPL aqueous extract (SCPLE) on platelet count, extramedullary ...
Varisha Anjum   +4 more
doaj   +1 more source

An interesting diagnosis for a presacral mass: case report [PDF]

open access: yes, 2009
A presacral mass can present a diagnostic dilemma for the surgical oncologist. Differential diagnoses include congenital causes such as teratoma or chordoma, neurological causes such as neurilemoma or neurofibroma or other malignancies such as lymphoma ...
Babazadeh, Sina   +3 more
core   +2 more sources

Single‐Cell Dissection Reveals Immune Dysregulation After CD5 or CD7‐Directed Chimeric Antigen Receptor T‐Cell Therapy

open access: yesAdvanced Science, Volume 13, Issue 8, 9 February 2026.
Single‐cell RNA/TCR/BCR sequencing reveals that 5CAR therapy in T‐ALL induces T‐cell exhaustion, reduces EBV‐associated TCRs, lowers TCR/BCR diversity, and increases NK/DC/monocyte activation and function. In contrast, 7CAR therapy reduces multiple pathogen‐associated TCRs, enhances NK cell activation and function, decreases monocyte activation, and ...
Yuechen Luo   +12 more
wiley   +1 more source

Extramedullary haematopoiesis causing spinal cord compression: A rare presentation with excellent outcome

open access: yesAnnals of Indian Academy of Neurology, 2007
Extramedullary haematopoiesis (EMH) as a cause of spinal cord compression in patients with thalassaemia major is very rare. Treatment of EMH includes the use of radiotherapy, hypertransfusion, laminectomy and chemotherapy in the form of hydroxyurea We ...
Talapatra Kaustav   +4 more
doaj  

Deficiency in Protein Tyrosine Phosphatase PTP1B shortens lifespan and leads to development of acute leukemia [PDF]

open access: yes, 2018
This work was performed with the funds from the Wellcome Trust ISSF grant to M. Delibegovic and BHF project grant to M. Delibegovic (PG/11/8/28703). S. Le Sommer is a recipient of the University of Aberdeen Institute of Medical Sciences PhD studentship ...
Bence, Kendra K.   +10 more
core   +3 more sources

Therapy‐Related Acute Myeloid Leukemia Following Plasma Cell Leukemia: A Case Report and Literature Review

open access: yesClinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT With the improvement of survival in multiple myeloma (MM), therapy‐related acute myeloid leukemia (t‐AML) has emerged as a clinically relevant second primary malignancy (SPM). We report a case of MM evolving into t‐AML after multi‐agent chemotherapy and review the literature on therapy‐related leukemias in MM.
Songdi Chen   +10 more
wiley   +1 more source

Oral mucosal manifestations with identical mutations to the bone marrow in a patient with VEXAS syndrome

open access: yes
Rheumatology &Autoimmunity, EarlyView.
Lilian Vasaitis   +5 more
wiley   +1 more source

Glucose‐6‐phosphate dehydrogenase deficiency is associated with improved survival in patients with acute myeloid leukemia treated with venetoclax and azacitidine

open access: yesCancer, Volume 132, Issue 3, 1 February 2026.
Abstract Background Glucose‐6‐phosphate dehydrogenase (G6PD) deficiency impairs cellular redox balance through reduced NADPH production and is the most common enzymatic disorder‐causing anemia. Venetoclax combined with azacitidine (Ven‐Aza) targets leukemic stem cells by disrupting oxidative phosphorylation and inducing mitochondrial stress. This study
Shira Buchrits   +7 more
wiley   +1 more source

A 26-yr-old female with persistent cough [PDF]

open access: yes, 2003
Not ...
Alper, H.   +5 more
core   +2 more sources

WRAP53 is Downregulated in Acute Myeloid Leukemia Patients and Positively Correlates With HTERT Expression

open access: yesCancer Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background Acute myeloid leukemia (AML) is a prevalent hematologic malignancy in adults, marked by clonal disorders in hematopoietic cells, rapid progression, and genetic heterogeneity. The WRAP53 gene, which is associated with genomic stability due to its involvement in activities, such as DNA repair, TP53 regulation, and association with ...
Renan Brito Gadelha   +14 more
wiley   +1 more source

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