Results 51 to 60 of about 25,864 (262)
TSHR‐Targeting Nucleic Acid Aptamer Treats Graves' Ophthalmopathy via Novel Allosteric Inhibition
This study presents YC3, a novel inhibitory TSHR‐targeting aptamer, as a promising therapeutic for Graves' ophthalmopathy (GO). YC3 suppresses pathological phenotypes in human orbital fibroblasts and improves outcomes in GO mice by binding to a previously unidentified allosteric site on TSHR, demonstrating the potential of aptamers in advancing ...
Yanchen Zhang +16 more
wiley +1 more source
A biomimetic eyeball system (BES) based on a 3‐DOF miniature origami mechanism, which addresses the inherent issues of large size and weight in traditional electromechanical BESs is presented. Moreover, it maintains a level of visual functionality comparable to that of the human eye, including capabilities such as rapid scanning, target recognition ...
Junji Pu +6 more
wiley +1 more source
Video-based Extraocular Muscles Learning Module
At the University of California, Los Angeles David Geffen School of Medicine, first-year medical students are taught the anatomy of the eyeball and its pertinent neurovascular structures, as well as that of the extraocular muscles during the ...
Jonathan Wisco +3 more
doaj +1 more source
Gaze‐Engineered 3D Augmented Reality
Augmented Reality (AR) systems serve as a critical interface bridging users with the metaverse. This study explores the application of human factors engineering in metaverse development, specifically investigating the integration of eye‐tracking technology to enhance AR display performance.
Naiqin Zhao +3 more
wiley +1 more source
Detailed analysis of slow oscillatory movements of eye position [PDF]
Our eyes make continuous movements even when attempting to fixate a stationary object. The involuntary eye movements occurring during fixation are referred to as fixational eye movements. There is a general agreement on three types of eye movements
Zhang, Bing
core +1 more source
Abstract Muscle architecture is a major determinant of muscle performance and, in mammalian lineages, has been correlated with both feeding ecology and locomotor behaviors. Over the past decade, contrast‐enhanced micro‐CT (DiceCT) has emerged as an alternative to traditional dissection‐based measurement.
Aleksandra Ratkiewicz +5 more
wiley +1 more source
A Core Head, Neck, and Neuroanatomy Syllabus for Physical Therapy Student Education
ABSTRACT Head, neck, and neuroanatomy are essential components of physical therapy education due to their broad clinical applications. Detailed syllabi exist for medical students, yet none have been developed for physical therapy. This study aimed to produce an International Federation of Associations of Anatomists core head, neck, and neuroanatomy ...
Stephanie J. Woodley +4 more
wiley +1 more source
Cerebellar Atrophy in Congenital Fibrosis of the Extraocular Muscles Type 1 [PDF]
We described a family with a molecularly confirmed form of CFEOM1 and a late-onset cerebellar syndrome. Brain MRI showed vermis atrophy in two older family members, who also manifested gait impairment, whereas both neurological examination and ...
Alessandra Tessa +8 more
core +1 more source
Myomaker and Myomixer are required for craniofacial myoblast fusion in zebrafish
Abstract Background Craniofacial and trunk skeletal muscles are derived from different progenitor populations during development. Trunk skeletal muscles contain mostly multinucleated myofibers that are formed through myoblast fusion. However, myoblast fusion in craniofacial muscles and its molecular regulation are not well understood.
Zhanxiong Zhang +3 more
wiley +1 more source
Simulating Extraocular Muscle Dynamics. A Comparison between Dynamic Implicit and Explicit Finite Element Methods [PDF]
Jorge Grasa, Begoña Calvo
openalex +1 more source

