Results 71 to 80 of about 16,684 (218)
Acta Ophthalmologica, Volume 104, Issue 1, Page e18-e27, February 2026.Abstract Purpose Patients with severe ocular motility restriction and/or large angle strabismus due to Graves' orbitopathy (GO) cannot be adequately addressed with conventional strabismus surgery using large muscle recessions. Muscle tendon elongation surgery, using a spacer of bovine pericardium (Tutopatch®) has emerged as a valuable alternative.
H. M. Jellema +7 more
wiley +1 more source
Metformin Restores Mitochondrial Function and Neurogenesis in POLG Patient‐Derived Brain Organoids
Advanced Science, Volume 13, Issue 4, 19 January 2026.Patient‐derived POLG‐mutant cortical organoids reveal neuronal subtype‐specific mitochondrial and synaptic defects, with dopaminergic neurons most affected. Metformin treatment restores neuronal identity, mitochondrial function, and excitability, increased mtDNA maintenance, and reprogrammed metabolism via TCA and redox pathways.
Zhuoyuan Zhang +6 more
wiley +1 more source
TSHR‐Targeting Nucleic Acid Aptamer Treats Graves' Ophthalmopathy via Novel Allosteric Inhibition
Advanced Science, Volume 13, Issue 4, 19 January 2026.This study presents YC3, a novel inhibitory TSHR‐targeting aptamer, as a promising therapeutic for Graves' ophthalmopathy (GO). YC3 suppresses pathological phenotypes in human orbital fibroblasts and improves outcomes in GO mice by binding to a previously unidentified allosteric site on TSHR, demonstrating the potential of aptamers in advancing ...
Yanchen Zhang +16 more
wiley +1 more source
Advanced Science, Volume 13, Issue 1, 5 January 2026.A biomimetic eyeball system (BES) based on a 3‐DOF miniature origami mechanism, which addresses the inherent issues of large size and weight in traditional electromechanical BESs is presented. Moreover, it maintains a level of visual functionality comparable to that of the human eye, including capabilities such as rapid scanning, target recognition ...
Junji Pu +6 more
wiley +1 more source
Brain and Behavior, Volume 16, Issue 1, January 2026.6/7 patients achieved CMI by the third follow‐up, sustained to the fourth follow‐up, and 4/6 reached MSE by the fifth follow‐up. First real‐world evidence of adding telitacicept efficacy in refractory ocular MG symptoms Abstract Introduction Refractory ocular myasthenia gravis (MG) represents a significant therapeutic challenge, as conventional ...
Jing Lin +4 more
wiley +1 more source
CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.A multicenter adult gMG cohort from five tertiary centers in China (N = 118) received efgartigimod 10 mg/kg IV weekly × 4. Early minimal symptom expression (MSE) response was defined as MG‐ADL ≤ 1 sustained ≥ 4 weeks and assessed within 4 weeks. A three‐factor nomogram (bulbar MG‐ADL subscore, FVC% predicted, serum IgG) was developed in the derivation ...
Yufang Yang +12 more
wiley +1 more source
Head &Neck, Volume 48, Issue 1, Page 148-159, January 2026.ABSTRACT Background Endoscopic surgical approaches for nasopharyngeal malignancies, including recurrent nasopharyngeal carcinoma (rNPC) and nasopharyngeal salivary gland tumors (NSGT), have seen significant development over the last decades. Our groups have expanded the classification of nasopharyngeal endoscopic resections (NER) from type 1 to 3 to ...
Francesco Boaria +20 more
wiley +1 more source
Veterinary Medicine and Science, Volume 12, Issue 1, January 2026.This case details a rare retrobulbar lymphoma with multifocal involvement. Diagnostic modalities included MRI/CT, cytology of various sites, immunophenotyping and PARR. These tests confirmed diverse cellular populations and Ig clonality across affected tissues. ABSTRACT Lymphoma is the most common malignant neoplasm in dogs.
Rankyung Jung +4 more
wiley +1 more source
Pediatric Anesthesia, Volume 36, Issue 1, Page 47-56, January 2026.ABSTRACT Background Preventive measures for postoperative vomiting (POV) in pediatric strabismus surgery are essential. Previous experimental studies have shown the independent antiemetic effects of propofol‐based total intravenous anesthesia (TIVA), dexamethasone (DEX), and ondansetron (OND).
Taiki Kojima +5 more
wiley +1 more source
An Electroencephalographic Investigation of the Impact of Eye Movements in a Memory Probe Task
Psychophysiology, Volume 63, Issue 1, January 2026.ABSTRACT Lateral saccades represent a major source of noise and confounds, particularly for event‐related potentials (ERPs) that rely on hemispheric imbalances in neural activity elicited by lateralized stimuli during central fixation. These include lateralized ERPs such as the contralateral delay activity (CDA), which indexes visual working memory ...
Alberto Petrin +4 more
wiley +1 more source