Results 21 to 30 of about 150,278 (286)

Predicting Pharmacokinetics of Active Constituents in Spatholobi caulis by Using Physiologically Based Pharmacokinetic Models

open access: yesPharmaceuticals
Background/Objectives: Spatholobi Caulis (SPC) is a medicinal plant that mainly grows in China and Southeast Asian countries and commonly used in clinics; the pharmacokinetic characteristics in humans need to be determined.
Xiaoyan Liu   +7 more
doaj   +1 more source

Research on signals extrapolation in the time domain based on wavelet analysis

open access: yesThe Journal of Engineering, 2019
Characteristic of modulation spectrum is important for radar targets classification and recognition, while signals with high occupation ratio cause low spectral resolution.
Huan Liu   +3 more
doaj   +1 more source

An advanced method of interpolation of short-focus electron beams boundary trajectories using higher-order root-polynomial functions and its comparative study

open access: yesSistemnì Doslìdženâ ta Informacìjnì Tehnologìï
The comparison of three advanced novel methods for estimating the boundary trajectory of electron beams propagated in ionized gas, including lower-order interpolation, self-connected interpolation, and extrapolation, as well as higher-order interpolation,
Igor Melnyk   +2 more
doaj   +1 more source

Predicting the Future Burden of Renal Replacement Therapy in Türkiye Using National Registry Data and Comparative Modeling Approaches

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic kidney disease is a growing public health problem worldwide, and the number of patients requiring renal replacement therapy is steadily increasing. Türkiye has experienced a similar rise in both the incidence and prevalence of renal replacement therapy over the past decades; however, national‐level projections of future ...
Arzu Akgül   +2 more
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Using Temporal Deep Learning Models to Estimate Daily Snow Water Equivalent Over the Rocky Mountains

open access: yesWater Resources Research
In this study we construct and compare three different deep learning (DL) models for estimating daily snow water equivalent (SWE) from high‐resolution gridded meteorological fields over the Rocky Mountain region.
Shiheng Duan   +3 more
doaj   +1 more source

Probabilistic Richardson extrapolation

open access: yesJournal of the Royal Statistical Society Series B: Statistical Methodology
Abstract For over a century, extrapolation methods have provided a powerful tool to improve the convergence order of a numerical method. However, these tools are not well-suited to modern computer codes, where multiple continua are discretized and convergence orders are not easily analysed.
Oates, Chris J.   +4 more
openaire   +4 more sources

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

extrapolation

open access: yes
Citation: 'extrapolation' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.14679 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
Rojas-Chavarro, Luisa Fernanda||   +1 more
  +6 more sources

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