Results 31 to 40 of about 153,437 (261)

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

Chemotherapy for Spinal Cord Intramedullary Pediatric Low‐Grade Glioma—A Systematic Literature Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko, Segev Gabay, Jonathan Roth, Amit Ringel, Rina Dvir, Shlomi Constantini   +5 more
wiley   +1 more source

A Fluid Flow‐Based Deep Learning (FFDL) Architecture for Subsurface Flow Systems With Application to Geologic CO2 Storage

Water Resources Research
Prediction of the spatial‐temporal dynamics of the fluid flow in complex subsurface systems, such as geologic CO2 storage, is typically performed using advanced numerical simulation methods that solve the underlying governing physical equations. However,
Zhen Qin, Yingxiang Liu, Fangning Zheng, Behnam Jafarpour   +3 more
doaj   +1 more source

An advanced method of interpolation of short-focus electron beams boundary trajectories using higher-order root-polynomial functions and its comparative study

Sistemnì Doslìdženâ ta Informacìjnì Tehnologìï
The comparison of three advanced novel methods for estimating the boundary trajectory of electron beams propagated in ionized gas, including lower-order interpolation, self-connected interpolation, and extrapolation, as well as higher-order interpolation,
Igor Melnyk, Alina Pochynok, Mykhailo Skrypka   +2 more
doaj   +1 more source

Classical Complement Pathway Inhibition in a Pediatric Patient With Refractory Immune Thrombocytopenia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric refractory immune thrombocytopenia (rITP) is generally characterized by persistent thrombocytopenia and failure to achieve a sustained response to multiple standard therapies. We report a 4‐year‐old female with congenital tufting enteropathy, post‐intestinal transplant patient on immunosuppressants, who developed severe rITP ...
Sarah Hsieh, Susmita Sarangi, Caileigh Pudela, Catherine M. Broome, Tara K. Suntum   +4 more
wiley   +1 more source

Potential Global-Local Inconsistency in Species-Area Relationships Fitting

Frontiers in Plant Science, 2016
The Species-Area Relationship (SAR) has been widely employed to assess species diversity and predict species extinction. Thus far, although many functions were proposed to fit SAR based on field observations or simulation results, the shape of SAR curve ...
Xubin Pan, Xiuling Zhang, Feng Wang, Shuifang Zhu   +3 more
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Using Temporal Deep Learning Models to Estimate Daily Snow Water Equivalent Over the Rocky Mountains

Water Resources Research
In this study we construct and compare three different deep learning (DL) models for estimating daily snow water equivalent (SWE) from high‐resolution gridded meteorological fields over the Rocky Mountain region.
Shiheng Duan, Paul Ullrich, Mark Risser, Alan Rhoades   +3 more
doaj   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

MEML: A Deep Data Augmentation Method by Mean Extrapolation in Middle Layers

IEEE Access, 2021
Data augmentation, generating new data that are similar but not same with the original data by making a series of transformations to the original data, is one of the mainstream methods to alleviate the problem of insufficient data.
Dongchen Liu, Lun Zhang, Xiansen Jiang, Caixia Su, Yufeng Fan, Yongfeng Cao   +5 more
doaj   +1 more source