Results 61 to 70 of about 21,362 (167)

Genetic intratumour heterogeneity in digestive high‐grade neuroendocrine neoplasms

Journal of Neuroendocrinology, Volume 38, Issue 10, October 2026.
Intratumour heterogeneity in digestive high‐grade neuroendocrine neoplasms. Abstract Digestive high‐grade neuroendocrine neoplasms (HG‐NEN) are rare and heterogeneous tumours with an aggressive biology and limited treatment efficacy. Genetic intratumour heterogeneity (ITH) is a mechanism of progression and treatment resistance in other cancers, yet ...
Siren Morken, Halfdan Sorbye, Wei Deng, Hatice Toprak Dogramaci, Andreas Venizelos, Lene Weber Vestermark, Per Pfeiffer, Geir Olav Hjortland, Christian Kersten, Eva Hofsli, Hege Elvebakken, Anne Couvelard, Inger Marie Bowitz Lothe, Aurel Perren, Stian Knappskog   +14 more
wiley   +1 more source

Low diagnostic yield of routine preoperative chest CT in patients undergoing partial nephrectomy: A national cohort study using UroCCR data (UroCCR n°216)

BJUI Compass, Volume 7, Issue 9, September 2026.
Abstract Objective The aim of this study was to evaluate the diagnostic yield and downstream clinical impact of routine preoperative chest CT in patients undergoing partial nephrectomy (PN) for localized renal cell carcinoma. Methods We conducted a retrospective multicentre study using data from the French Urological Cancer Comprehensive Cohort (UroCCR)
Ali Bourgi, Gaëlle Margue, Pierre Bigot, Norbert De Brek, Louis Surlemont, Martin Lorette, Nicolas Branger, Thomas Prudhomme, Aurélien Adypagavane, Véra Chatain, Thibaut Waeckel, Alexis Fontenil, Victor Gaillard, Jean‐Jacques Patard, Constance Michel, Julien Guillotreau, Olivier Belas, Maxime Vallée, Stéphane De Vergie, Jean‐Baptiste Beauval, Clément Sarrazin, Benjamin Delattre, Frédéric Panthier, Lionel Hoquetis, Romain Boissier, Julien Anract, Marie Chicaud, Alexandre Marsaud, Richard Mallet, Quentin‐Côme Le Cerlc, Khalil Chalhoub, Idir Ouzaid, Jean‐Christophe Bernhard, Franck Bruyère   +33 more
wiley   +1 more source

Hypercalcemic type of small cell carcinoma of the ovary [PDF]

Vojnosanitetski Pregled, 2015
Introduction. Extrapulmonary small cell carcinoma is a rare, prognostically bad tumor category. Primary, it can be localized in every organ, even in the ovary, where, due to its clinical specificities, it represents a challenge in diagnosis, as ...
Ilić Milena B., Jovanović Dalibor V., Milosavljević Miloš Z., Stanković Vesna, Đorđević Gordana, Protrka Zoran, Nedović Jasmina, Mitrović Slobodanka Lj.   +7 more
doaj   +1 more source

Artificial Intelligence Resources for the Screening of Titles and Abstracts in Systematic Reviews: A Scoping Review

Cochrane Evidence Synthesis and Methods, Volume 4, Issue 5, September 2026.
ABSTRACT Introduction Artificial intelligence (AI) is a branch of technology enabling machines to emulate complex human skills; it can also entail problem‐solving using bioinspired methods. It is used for automating systematic literature reviews (SLR), that is, defining a clinical question, locating relevant literature, preliminary screening, study ...
Ana M. Barragán, Sara Elena Ortiz Bonett, Eliana‐Isabel Rodríguez‐Grande, Alvaro David Orjuela‐Cañón, Oscar J. Perdomo, Guillermo Sánchez‐Vanegas   +5 more
wiley   +1 more source

Phase II Trial of First-Line Durvalumab and Chemotherapy in Patients With Extra-Pulmonary Small Cell Carcinoma

JTO Clinical and Research Reports
Introduction: Prospective randomized trials are lacking in extensive-stage or metastatic extra-pulmonary small cell carcinoma (EPSCC). As a result, treatment for EPSCC is largely extrapolated from SCLC studies.
Peey-Sei Kok, PhD, Bryan Chan, MMed (Clin Epi), Mason Aberoumand, MAppStat, Alison Zhang, PhD, Ken O’Byrne, MD, Subotheni Thavaneswaran, PhD, Frank Lin, PhD, Maya Kansara, PhD, Theresa Corpuz, BSc (Hons), Patrick Wheeler, BS, Robert John Simes, PhD, David Thomas, PhD, Chee Khoon Lee, PhD   +12 more
doaj   +1 more source

Extrapulmonary small cell sarcinoma: involvement of the brain without evidence of extracranial malignancy by serial PET/CT scans

World Journal of Surgical Oncology, 2008
Background Extrapulmonary small cell carcinoma (EPSCC) involving the brain is a rare manifestation of an uncommon tumor type. Case presentation We report a 59 year-old Caucasian female diagnosed with an EPSCC involving the left parietal lobe without ...
Havlioglu Necat, Osman Medhat, Nguyen Nghi C, Hueser Christopher N, Patel Anjali J   +4 more
doaj   +1 more source

Precise delineation of radiation targets for thoracic tumors in the immunotherapy era: From immune mechanisms to clinical practice

Precision Radiation Oncology, Volume 10, Issue 3, Page 371-387, September 2026.
RT‐immunotherapy synergy for thoracic tumors relies on precise target delineation to protect immune components. IFI, reduced volumes, and optimized positioning minimize damage, while multimodal imaging, DL, PBT, and FLASH‐RT enhance control. These innovations shift RT to an immune‐centric model, improving lung and esophageal cancer outcomes.
Xiaoying Chen, Minxiao Yi, Yu Deng, Qian Shen   +3 more
wiley   +1 more source

Clinically Important Emerging and Uncommon Fungal Pathogens in Asia: Epidemiology, Antifungal Resistance and Challenges in Diagnosis and Management

Mycoses, Volume 69, Issue 9, September 2026.
ABSTRACT Fungal infections in Asia are influenced by warm, humid climates, high population density and expanding healthcare systems, which together facilitate the emergence, transmission and detection of both common and rare pathogens. While Candida and Aspergillus species remain the leading causes of invasive fungal disease, increasing attention has ...
Narut Chancharussin, Anupop Jitmuang, Arunaloke Chakrabarti, Methee Chayakulkeeree   +3 more
wiley   +1 more source

Extrapulmonary Small Cell Carcinoma of the Liver: Clinicopathological and Immunohistochemical Findings

Yonsei Medical Journal, 2007
Patients with primary small cell carcinoma of the liver have rarely been described in medical literature. Knowledge of clinical, pathological and immunohistochemical properties remains limited. We described an 82-year-old female patient with primary small cell carcinoma of the liver.
Choi, Suk Jin, Kim, Joon Mee, Han, Jee Young, Ahn, Seung Ik, Kim, Jin-Soo, Kim, Lucia, Park, In Suh, Chu, Young Chae   +7 more
openaire   +2 more sources

Cigarette Smoke‐Exposed Alveolar Epithelial Cell‐Derived Exosomes Exacerbate Skeletal Muscle Dysfunction Through HDAC2 Signalling

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 4, August 2026.
ABSTRACT Background Skeletal muscle dysfunction (SMD) is a common extrapulmonary complication of chronic obstructive pulmonary disease (COPD). Histone deacetylase 2 (HDAC2) is closely involved in the suppression of inflammatory transcription and is progressively reduced during COPD progression.
Chao Li, MingZhi Ou, Gang Jiang, GuiXian Zheng, YongLiang Jiang   +4 more
wiley   +1 more source