Results 51 to 60 of about 20,803 (264)

Classification of Acute Respiratory Distress Syndrome

Общая реаниматология, 2007
The editorial proposes a new classification of acute respiratory distress syndrome (ARDS). Acute lung injury (ALI) is regarded as the first stage of ARDS.
V. V. Moroz, A. M. Golubev
doaj   +1 more source

Effect of varying driving pressure and respiratory rate on ventilator‐induced lung injury in healthy and injured lungs: An experimental animal study

The Journal of Physiology, Volume 604, Issue 3, Page 1463-1484, 1 February 2026.
Abstract figure legend Top: experimental groups for the two series of rats: five combinations of driving pressure (DP) and respiratory rate (RR), maintaining a constant 4DP+RR value of 140, were applied for 4 h in healthy lungs (Series 1) and 2 h in HCl‐injured lungs (Series 2).
Davide Raimondi Cominesi, Vanessa Zambelli, Emma J. Murphy, Roberta Garberi, Aurora Magliocca, Roberto Fumagalli, Giacomo Bellani, Giuseppe Foti, Maurizio Cereda, John G. Laffey, Emanuele Rezoagli   +10 more
wiley   +1 more source

Acute kidney injury in adults receiving extracorporeal membrane oxygenation

Journal of the Formosan Medical Association, 2014
Extracorporeal membrane oxygenation (ECMO) has been utilized for critically ill patients such as patients with postcardiotomy cardiogenic shock or life-threatening respiratory failure.
Yung-Chang Chen, Feng-Chun Tsai, Ji-Tseng Fang, Chih-Wei Yang   +3 more
doaj   +1 more source

Ultrasound‐derived velocity variations predict fluid responsiveness in critically ill pediatric oncology patients

Physiological Reports, Volume 14, Issue 3, February 2026.
Abstract Dynamic ultrasound indices assess preload‐dependent changes in stroke volume via the Frank–Starling mechanism and guide fluid therapy. This study aimed to determine optimal cutoff values for ultrasound‐derived peak aortic (ΔVAo) and carotid (ΔVCa) velocity variations to predict fluid responsiveness in critically ill pediatric oncology patients.
Bruno Sanchez Camargo, Orlei Ribeiro de Araujo, Dafne Cardoso Bourguignon da Silva   +2 more
wiley   +1 more source

RNA interference for CFTR attenuates lung fluid absorption at birth in rats

Respiratory Research, 2008
Background Small interfering RNA (siRNA) against αENaC (α-subunit of the epithelial Na channel) and CFTR (cystic fibrosis transmembrane conductance regulator) was used to explore ENaC and CTFR function in newborn rat lungs.
Folkesson Hans G, Koshy Shyny, Li Tianbo
doaj   +1 more source

Near-Normal Values of Extravascular Lung Water in Children [PDF]

Pediatric Critical Care Medicine, 2015
To define near-normal values of extravascular lung water indexed to body weight in children.Prospective multicenter observational study.Medical/surgical PICUs of 5 multinational hospitals.Fifty-eight children with a median age of 4 years (range 1 month to 17 year) with heterogeneous PICU admission diagnoses were included.
Nusmeier, A., Cecchetti, C., Blohm, M., Lehman, R., Hoeven, J.G. van der, Lemson, J.   +5 more
openaire   +3 more sources

Venous Vessel Size Imaging Derived From A Breath‐Hold Task

NMR in Biomedicine, Volume 39, Issue 1, January 2026.
In this study, we propose the utilization of a spin‐ and gradient‐echo echo‐planar imaging approach, in conjunction with a numerical simulation, for the quantitative assessment of venous vessel size measurements during a breath‐hold task. ABSTRACT Vessel size imaging (VSI) to provide a measure of vessel radius in the brain has been demonstrated using ...
Ke Zhang, Artur Hahn, Simon M. F. Triphan, Mark O. Wielpütz, Christian H. Ziener, Mark E. Ladd, Heinz‐Peter Schlemmer, Hans‐Ulrich Kauczor, Oliver Sedlaczek, Felix T. Kurz   +9 more
wiley   +1 more source

Goal-directed therapy in intraoperative fluid and hemodynamic management. [PDF]

, 2013
Intraoperative fluid management is pivotal to the outcome and success of surgery, especially in high-risk procedures. Empirical formula and invasive static monitoring have been traditionally used to guide intraoperative fluid management and assess volume
Gutierrez, Maria Cristina, Liu, Hong, Moore, Peter G   +2 more
core   +1 more source

Physiologically‐Based Pharmacokinetic Modeling to Support Pediatric Clinical Development: An IQ Working Group Perspective on the Current Status and Challenges

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 1, January 2026.
ABSTRACT Pediatric extrapolation strategies issued by health authorities have streamlined pediatric drug development and reduced the unnecessary burden of conducting pediatric clinical studies. In line with these strategies, physiologically based pharmacokinetic (PBPK) models have been utilized extensively for initial dosing regimen and sampling ...
James W. T. Yates, Michael Zientek, Kunal S. Taskar, Wen Lin, Tycho Heimbach, Stefan Willmann, Jessica Rehmel, Neil Parrott, Michael Hanley, Justine Badee, Yuan Chen, Susan Cole, Loeckie De Zwart, Sebastian Haertter, Rongrong Jiang, Masakatsu Kotsuma, Guiqing Liang, Yu‐Wei Lin, Jing Liu, Ying Ou, Juliane Rascher, Naveed A. Shaik, Jan Wahlstrom, Xiaofeng Wang, Guangqing Xiao, Ka Lai Yee, S. Y. Amy Cheung   +26 more
wiley   +1 more source

High molecular weight sodium hyaluronate improves survival of syndecan-1-deficient septic mice by inhibiting neutrophil migration.

PLoS ONE, 2021
MethodsSepsis was induced by cotton smoke inhalation followed by intranasal administration of Pseudomonas aeruginosa in female (> 6 months) Balb/c and syndecan-1 knockout mice. Survival of mice, lung capillary endothelial glycocalyx integrity, lung water
Tuvshintugs Baljinnyam, Enkhtuya Radnaa, Casey M Ouellette, Christina Nelson, Yosuke Niimi, Clark R Andersen, Vsevolod Popov, Jae-Woo Lee, Donald S Prough, Perenlei Enkhbaatar   +9 more
doaj   +1 more source