Results 71 to 80 of about 721,614 (296)

Baseline Neuroinflammation Stratifies TSPO‐PET Response to Disease‐Modifying Therapy in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate which baseline clinical and imaging characteristics best predict TSPO‐PET‐measurable reduction in glial activation following treatment of multiple sclerosis (MS), to utilize this information for designing more efficient biomarker‐based clinical trials targeting glial activation.
Marlene T. Morch   +5 more
wiley   +1 more source

Extremal correlation coefficient for functional data

open access: yesBiometrika
Abstract We propose a coefficient that measures extremal dependence in paired samples of functions. It has properties similar to the Pearson correlation, but differs in two significant ways: (i) it is designed to measure dependence between curves; and (ii) it focuses only on extreme curves.
Kim, Mihyun, Kokoszka, Piotr
openaire   +2 more sources

Extremal behavior of stochastic volatility models [PDF]

open access: yes, 2005
Empirical volatility changes in time and exhibits tails, which are heavier than normal. Moreover, empirical volatility has - sometimes quite substantial - upwards jumps and clusters on high levels.
Lindner, Alexander M.   +7 more
core   +1 more source

White Matter and Perivascular Imaging Changes in Alzheimer's Disease and Cerebral Amyloid Angiopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peak‐width of skeletonized mean diffusivity (PSMD) and diffusion tensor imaging–analysis along the perivascular space (DTI‐ALPS), reflecting white matter integrity and glymphatic function, are altered in Alzheimer's disease (AD).
Debina Laishram   +3 more
wiley   +1 more source

On the Growth of Solutions of a Class of Higher Order Linear Differential Equations with Extremal Coefficients

open access: yesAbstract and Applied Analysis, 2014
We consider that the linear differential equations f(k)+Ak-1(z)f(k-1)+⋯+A1(z)f′+A0(z)f=0, where Aj  (j=0,1,…,k-1), are entire functions. Assume that there exists l∈{1,2,…,k-1}, such that Al is extremal for Yang's inequality; then we will give some ...
Jianren Long, Chunhui Qiu, Pengcheng Wu
doaj   +1 more source

Association Between Neurofilament Light Chain and Real‐World Ambulatory Function in Progressive MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurofilament light chain (NfL) is a biomarker of neuroaxonal injury in multiple sclerosis (MS), yet associations with functional outcomes remain unclear. Longitudinal associations between serum NfL (sNfL) and daily step count (STEPS) from wearable devices were assessed in a large international progressive MS cohort.
Gabby B. Joseph   +5 more
wiley   +1 more source

Transport coefficients, membrane couplings and universality at extremality [PDF]

open access: yesJournal of High Energy Physics, 2010
29 pages, v2: Small text changes for clarity, typos ...
openaire   +3 more sources

Validation of Patient‐Reported Outcomes Measurement Information System (PROMIS) Pediatric Measures for Children With Chronic Nonbacterial Osteomyelitis

open access: yesArthritis Care &Research, EarlyView.
Objective To assess the validity of the Patient‐Reported Outcomes Measurement Information System (PROMIS) Pediatric measures in patients with chronic nonbacterial osteomyelitis (CNO). Methods Within the longitudinal patient registry of CNO, English‐speaking patients aged 8 years and older self‐reported PROMIS Pediatric measures of fatigue, pain ...
Mary M. Eckert   +43 more
wiley   +1 more source

Rare Events, Temporal Dependence and the Extremal Index [PDF]

open access: yes
AMS classifications: 60G70; 62G32;block maximum;exceedance;extremal index;failure set;mixing condition;M4 process;rare event;stationary ...
Segers, J.J.J.
core  

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