Results 111 to 120 of about 34,637 (273)

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization

Advanced Science, EarlyView.
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin, Mengjie Zhang, Wenying Liu, Wenlong Shen, Debao Li, Hongming Miao, Fang Deng, Gang Zhang, Yi Tian, Yi Zhang, Zhihu Zhao, Bing Ni   +11 more
wiley   +1 more source

Application of Symmetric Division Deg Index of Graph Under Fuzzy Environment

International Journal of Computational Intelligence Systems
Fuzzy graph theory, renowned for its capacity to manage uncertainty and capture varying degrees of relationships, has surfaced as a powerful framework for modeling and addressing complex problems across diverse domains such as medicine, social networks ...
Umapada Jana, Ganesh Ghorai
doaj   +1 more source

Some new results in extremal graph theory [PDF]

, 2011
In recent years several classical results in extremal graph theory have been improved in a uniform way and their proofs have been simplified and streamlined. These results include a new Erd s-Stone-Bollob s theorem, several stability theorems, several saturation results and bounds for the number of graphs with large forbidden subgraphs.
openaire   +2 more sources

Engineered Living Systems With Self‐Organizing Neural Networks: From Anatomy to Behavior and Gene Expression

Advanced Science, EarlyView.
Ectodermal tissue excised from Xenopus embryos self‐organizes into a three‐dimensional mucociliary organoid. Here, we generate a neural variant, termed neurobot, by implanting neural precursor cells. Neurobots develop mature neurons, adopt distinct morphologies, exhibit more complex motility, and respond differentially to neuroactive compounds. Imaging
Haleh Fotowat, Laurie O'Neill, Léo Pio‐Lopez, Megan M. Sperry, Patrick Erickson, Tiffany Lin, Michael Levin   +6 more
wiley   +1 more source

Hypergraphs and simplicial complexes in focus: a roadmap for future research in higher-order interactions

Journal of Physics: Complexity
Higher-order interactions are increasingly being recognized as fundamental to our understanding of complex systems, networks, and the development of the next generation of AI algorithms.
Aida Abiad, Alex Arenas, Ágnes Backhausz, József Balogh, Christopher R S Banerji, Sergio Barbarossa, Ginestra Bianconi, Christian Bick, Magnus Botnan, Timoteo Carletti, Lucia Cavallaro, Andrea Civilini, Tina Eliassi-Rad, Xue Gong, Krystal Guo, Heather Harrington, Jürgen Jost, P L Krapivsky, Pietro Liò, Ben D MacArthur, Carolina Mattsson, Pedro A M Mediano, Ana P Millan, Raffaella Mulas, Alice Patania, Giovanni Petri, Cerene Rathilal, Rubén J Sánchez-García, Martina Scolamiero, Michael T Schaub, Hanlin Sun, Yu Tian, Francesco Vaccarino, Kelin Xia   +33 more
doaj   +1 more source

Detection of Protein–Protein Interactions in Escherichia coli With Single Molecule Sensitivity

Advanced Science, EarlyView.
This article describes a regulatory circuit in Escherichia coli able to detect protein–protein interactions with exquisite sensitivity. The interaction between two hybrid proteins fused to Bordetella pertussis adenylate cyclase and its activator calmodulin triggers a potent cyclic AMP signaling cascade.
Marilyne Davi, Daniel Ladant
wiley   +1 more source

Unraveling the Molecular Mechanisms Underlying Spontaneous Multipolar Mitosis Through CIN‐seq

Advanced Science, EarlyView.
Multipolar mitosis, a hallmark of chromosomal instability (CIN), drives tumor heterogeneity but is challenging to study in live cells. Using CIN‐seq, a single‐cell multiomics method, we profiled rare CIN events and identified mechanisms associated with viable multipolar mitosis, including PTEN attenuation, Rho GTPase‐driven cytokinesis failure, and ...
Pin‐Rui Su, Ting‐Chun Chou, Maria Teresa López‐Cascales, Junfeng Huang, Tsai‐Ying Chen, Sjoukje van Wieren, Chan Li, Cecile Beerens, Li You, Jelle Storteboom, Miao‐Ping Chien   +10 more
wiley   +1 more source

Undecidability of polynomial inequalities in weighted graph homomorphism densities

Forum of Mathematics, Sigma
Many problems and conjectures in extremal combinatorics concern polynomial inequalities between homomorphism densities of graphs where we allow edges to have real weights.
Grigoriy Blekherman, Annie Raymond, Fan Wei   +2 more
doaj   +1 more source

In Situ X‐Ray Tomography and Acoustic Emission Monitoring of Damage Evolution in C/C‐SiC Composites Fabricated by Liquid Silicon Infiltration

Advanced Science, EarlyView.
This study investigates how the internal structure of fiber‐reinforced ceramic composites affects their resistance to damage. By combining 3D X‐ray imaging with acoustic emission monitoring during mechanical testing, it reveals how silicon distribution influences crack formation.
Yang Chen, Renato S. M. Almeida, Stefan Flauder, Guillaume Couégnat, Kamen Tushtev, Jürgen Horvath, Peter Wriggers, Kurosch Rezwan   +7 more
wiley   +1 more source

Estimating the First, Hyper-Zagreb Index for Direct Product of F-Sum Graphs

Mathematics
A chemical graph is an illustration of a chemical compound’s structural formula, where the edges indicate covalent bonding and the vertices depict atoms.
Suha Wazzan, Rauf Irshad
doaj   +1 more source