Results 41 to 50 of about 4,778,088 (249)

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Extremal broadcasting problems

open access: yesDiscrete Applied Mathematics, 1989
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Extremal problems for logarithmic capacity and extremal length.

open access: yes, 1995
We solve extremal problems for two conformal invariants in the complex plane, logarithmic capacity and extremal length. For a finitely-connected domain $\Omega$ containing $\infty ,$ with boundary $\Gamma ,$ the logarithmic capacity $d(\Gamma )$ is ...
Thurman, Robert Ellis, III
core   +7 more sources

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

Optimal Difference Formulas in the Sobolev Space

open access: yesСовременная математика: Фундаментальные направления, 2022
Optimization of computational methods in functional spaces is one of the main problems of computational mathematics. In this paper, algebraic and functional assertions for the problem of difference formulas are discussed.
Kh. M. Shadimetov, R. N. Mirzakabilov
doaj   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi   +8 more
wiley   +1 more source

On Some Extremal Problems on Linearly Invariant Classes

open access: yesNonlinear Analysis, 2005
In present paper the definition of linearly invariant class of analytical in the right half-plane is given and some extremal problems on introduced class are solved.
E. G. Kiriyatzkii, J. Kirjackis
doaj   +1 more source

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