Results 71 to 80 of about 1,552,101 (301)

Terrestrial carbon losses from mountaintop coal mining offset regional forest carbon sequestration in the 21st century

Environmental Research Letters, 2012
Studies that quantify the spatial and temporal variability of carbon sources and sinks provide process-level information for the prediction of future levels of atmospheric carbon dioxide as well as verification of current emission agreements. Assessments
J Elliott Campbell, James F Fox, Peter M Acton   +2 more
doaj   +1 more source

Insights into a long life without cancer: The case of the bowhead whale

Molecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Nonparametric Bayesian Inference on Bivariate Extremes [PDF]

, 2010
The tail of a bivariate distribution function in the domain of attraction of a bivariate extreme-value distribution may be approximated by the one of its extreme-value attractor.
Guillotte, Simon, Perron, Francois, Segers, Johan   +2 more
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

CHARACTERIZATION OF PRECIPITATION EXTREMES AND TRENDS IN TWO REGIONS OF NORTH AFRICA [PDF]

Aerul şi Apa: Componente ale Mediului, 2015
To identify extreme precipitation, we use the “Standardized Precipitation Index” (SPI) method designed to determine periods of climatic drought. This research attempts to assess the synchronization of cycles of precipitation and trends in two regions of ...
ZEINEDDINE N., MURĂRESCU O.
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Prediction of extreme events in the OFC model on a small world network

, 2010
We investigate the predictability of extreme events in a dissipative Olami-Feder-Christensen model on a small world topology. Due to the mechanism of self-organized criticality, it is impossible to predict the magnitude of the next event knowing previous
A. Corral, A. Corral, A. Garber, A. Garber, A. Helmstetter, D. Marsan, D.J. Watts, E. Casarotti, F. Caruso, F. Caruso, F. Caruso, H. Kantz, J. Neyman, L. Crescentini, M.S. Mega, M.S. Mega, P. Bak, P. Bak, P. Tosi, P.A. Varotsos, S. Abe, S. Lise, T. Parsons, X. Yang, Y.Y. Kagan, Z. Olami   +25 more
core   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

Event Rate for Extreme Mass Ratio Burst Signals in the LISA Band

, 2006
Stellar mass compact objects in short period orbits about a $10^{4.5}$--$10^{7.5}$ solar mass massive black hole (MBH) are thought to be a significant continuous-wave source of gravitational radiation for the ESA/NASA Laser Interferometer Space Antenna ...
Finn, Lee Samuel, Holley-Bockelmann, Kelly, Rubbo, Louis J.   +2 more
core   +1 more source