Results 41 to 50 of about 467,998 (337)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Development of a Website-based Inventory Information System at Konveksi Mitra Jaya Abadi

open access: yesSistemasi: Jurnal Sistem Informasi
The utilization of information technology has increased the demand for more efficient and accurate inventory management systems, particularly for businesses such as Mitra Jaya Abadi Garment Company, which previously relied on manual record-keeping.
Dian Indrianita, Riduwan Napianto
doaj   +1 more source

Extreme Programming Study Method Case Study on Designing of Accounting Term Dictionary [PDF]

open access: yes, 2014
Extreme Programming (XP) is a software development method that is simple and includes one of the agile methods pioneered by Kent Beck, Ron Jeffries, and Ward Cunningham. The main purpose of the Extreme Programming method is to reduce the cost of software
Ependi, U. (Usman)   +1 more
core  

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

open access: yesMolecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor   +2 more
wiley   +1 more source

Insights into a long life without cancer: The case of the bowhead whale

open access: yesMolecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

Applying XP Ideas Formally: The Story Card and Extreme X-Machines [PDF]

open access: yes, 2003
By gathering requirements on story cards extreme programming (XP) makes requirements collection easy. However it is less clear how the story cards are translated into a finished product.
Holcombe, W., Thomson, C.
core   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Hoopoe: Simulation of Extreme Programming [PDF]

open access: yes, 2018
Experts agree that “smart” communication are an interesting new topic in the field of cryptography, and systems engineers concur. In our research, we verify the visualization of DNS [34].
Frias, C. (Cynthia)   +3 more
core  

Intercompartmental communication in senescence

open access: yesFEBS Open Bio, EarlyView.
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz   +3 more
wiley   +1 more source

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