Results 51 to 60 of about 1,641,561 (255)

Sistem Penjadwalan dan Presensi Adaptif untuk Optimalisasi Manajemen Operasional di Rumah Sakit

Edumatic
Mataram University Hospital faces problems in managing work schedules that are still manual using excel and are not integrated with the attendance system. This has an impact on operational management in hospitals that are less than optimal. This research
Gita Mailand Sari, Ida Bagus Ketut Widiartha, Herliana Rosika   +2 more
doaj   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Arquitectura Hexagonal y Microservicios para la Digitalización de Procesos Administrativos en una Institución Pública: Caso de Gestión de Vacaciones y Permisos

Informática y Sistemas
Gestionar vacaciones, licencias y permisos con hojas de cálculo genera errores, duplicados y baja trazabilidad. Para atender esta problemática, este trabajo documenta el diseño, desarrollo y evaluación del sistema GIATH, orientado a centralizar y ...
Britney Paulette Tenecela Tocto, Kevin Joel Zuñiga Iñiguez, Bertha Mazón Olivo, Damar Alejandra Taylor Vivanco   +3 more
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Rancang bangun sistem survei kepuasan pemangku kepentingan berbasis web di Politeknik Negeri Banyuwangi

Jurnal Eltek
Politeknik Negeri Banyuwangi masih menghadapi kendala dalam melakukan survei kepuasan secara efektif dan efisien. Metode survei yang saat ini digunakan kurang praktis dan hasilnya sulit diolah.
Alisa Nuril Jazilah, Junaedi Adi Prasetyo, Indira Nuansa Ratri, Subono Subono, Lutfi Hakim   +4 more
doaj   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

RANCANG BANGUN SISTEM PEMBAYARAN AIR MENGGUNAKAN EXTREME PROGRAMMING [PDF]

, 2022
Desa Giritirto, Purwosari, Gunung Kidul Giritirto, Purwosari, Gunung Kidul Giritirto, Purwosari, Gunung KidulGiritirto, Purwosari, Gunung Kidul Giritirto, Purwosari, Gunung Kidul Giritirto, Purwosari, Gunung KidulGiritirto, Purwosari, Gunung Kidul ...
Muhammad Fauzi Robbani, NIM. 15650004
core   +1 more source

EXTREME PROGRAMMING AND RATIONAL UNIFIED PROCESS – CONTRASTS OR SYNONYMS? [PDF]

The agile movement has received much attention in software engineering recently. Established methodologies try to surf on the wave and present their methodologies a being agile, among those Rational Unified Process (RUP).
Ionel IACOB
core