Results 51 to 60 of about 822,899 (303)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Open Source Tools to Support Teaching Agile Software Development [PDF]

open access: yes, 2014
Learning agile software development methodologies are important due to the popularity of agility in software industry. Agile software development has several practices and each practice needs specific tools to work with.
Adhy, Satriyo, Wisnu Wirawan, Panji
core  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

An ontology of agile aspect oriented software development [PDF]

open access: yes, 2011
Both agile methods and aspect oriented programming (AOP) have emerged in recent years as new paradigms in software development. Both promise to free the process of building software systems from some of the constraints of more traditional approaches.
Parsons, David
core  

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

open access: yesFEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso   +4 more
wiley   +1 more source

Flexibility and resilience in equity-centered research: lessons learned conducting a randomized controlled trial of a family-based substance use prevention program for American Indian families

open access: yesFrontiers in Public Health
Meaningful and effective community engagement lies at the core of equity-centered research, which is a powerful tool for addressing health disparities in American Indian (AI) communities.
Nancy L. Asdigian   +9 more
doaj   +1 more source

Online tools for virtual pair programming [PDF]

open access: yes, 2009
As agile methodologies advance in process maturity we find that most of their practices such as Test-Driven Development, refactoring, and pair programming (specifically for Extreme Programming) are becoming the order of the day in a number of ...
Mnkandla, E.
core  

Bridging the gap between research and agile practice: an evolutionary model [PDF]

open access: yes, 2015
There is wide acceptance in the software engineering field that industry and research can gain significantly from each other and there have been several initiatives to encourage collaboration between the two.
Barroca, Leonor   +4 more
core   +1 more source

Use of Symptomatic Drug Treatment for Fatigue in Multiple Sclerosis and Patterns of Work Loss

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To describe the use of central stimulants and amantadine for fatigue in MS and evaluate a potential association with reduced work loss in people with MS. Methods We conducted a nationwide, matched, register‐based cohort study in Sweden (2006 to 2023) using national registers with prospective data collection.
Simon Englund   +3 more
wiley   +1 more source

Teorizando as Práticas dos Métodos Ágeis no Desenvolvimento de Software Visando ao Processo de Inovação das Empresas

open access: yesTeoria e Prática em Administração, 2011
Brazilian IT executives are being challenged to play an active and important role in the innovation process within their organizations. The purpose of this study is to explore agile software development methods in facing this challenge.
Dolci, Décio Bittencourt
doaj  

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